Name

FGF8/17/18>Pax3/7::WRPW (Stolfi 2011)

Targeted Gene

(PAX3; PAX6; PAX7)

Family

Sequence-based

Type

overexpression_construct

Supplier

Comment

FGF8/17/18 cis-regulatory region drives Pax3/7 dominant negative. Pax3/7::WRPW was made by fusing the N-terminal paired box and homeodomain (aa 3-253) to WRPW.

Regulation

Loss of function

Publication

Stolfi et al. (2011). Neural tube patterning by Ephrin, FGF and Notch signaling relays. Development 138(24):5429-39