Name

Mesp>Mek_S220E-S216D

Targeted Gene

(MAP2K1; MAP2K2; MAP2K5)

Family

Sequence-based

Type

overexpression_construct

Supplier

Comment

Constitutively active MekS216D,S220E mutant expression is driven by Mesp minimal enhancer (REG00000089) in the B7.5 cell pair.

Regulation

Gain of function

Publication

Razy-Krajka et al. (2018). An FGF-driven feed-forward circuit patterns the cardiopharyngeal mesoderm in space and time. Elife 7():