Name

Ttf-GATAa-WRPW

Targeted Gene

(GATA4; GATA5; GATA6)

Family

Sequence-based

Type

null

Supplier

n/a

Comment

The Ttf-GATAa-WRPW construct is used to disrupt GATAa activity by expressing the dominant negative repressor GATAa-WRPW using the characterized pan-endoderm enhancer for thyroid transcription factor Ttf-1, also known as Titf-1.

Regulation

Loss of function

Publication

Ragkousi et al. (2011). A single GATA factor plays discrete, lineage specific roles in ascidian heart development. Dev. Biol. 352(1):154-63