Name

tALK4/5/7 mRNA

Targeted Gene

(ACVR1B; ACVR1C; TGFBR1)

Family

Sequence-based

Type

null

Supplier

n/a

Comment

Truncated version of ci-ALK4/5/7, in which the cytoplasmic domain was removed, act as a dominant negative.
The extracellular and transmembrane domains was PCR amplified from Ci-ALK4/5/7 cDNA (cieg008p16) with the primer 5 -GGGATCCACCATGAACTGTTTATC-AATTCTATTCC- 3 and 5 -GGGATCCTTAGTCCAAGAGATC-TTGCATGT-3 .

Regulation

Loss of function

Publication

n/a