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MOLECULAR TOOL

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  1. EST 'AV678166'
  2. Transcript 'KH2012:KH.L149.21.v2...'
  3. Molecular Tool 'Ci-bmp::Ci-Tbx6b'
  4. Molecular Tool 'Su(H)DBM'

Molecular tool card for 'Su(H)DBM'

Name

Su(H)DBM

Targeted Gene

(RBPJ; RBPJL)

Family

Sequence-based

Type

null

Supplier

n/a

Comment

DNA-binding mutant of Ciona Suppressor of Hairless [Ci-Su(H)DBM]. This mutant form of Su(H) still binds to NICD, but not to its target DNA sequences, thus interfering with the ability of NICD to interact with endogenous Su(H) proteins (Wettstein et al.,1997).

Regulation

Loss of function

Publication

n/a

Sequence

SU(H)DBM-F,5\'-CAACGAACTCGAATCACAGACAGTGAGCCACAGAGTCCCTGC-3\
';SU(H)DBM-R,5\'-GCAGGGACTCTGTGCTCACTGTCTGTGATTCGAGTTCGTTG-3
\'.