Name

pFog>Msxb

Targeted Gene

(DLX1; MSX1; MSX2)

Family

Sequence-based

Type

overexpression_construct

Supplier

n/a

Comment

“We have used electroporation-mediated overexpression using an independent ectodermal drivers. The promoter of Fog has pan-ectodermal activity from the 16-cell stage ( Pasini et al., 2006 ; Rothbacher et al., 2007). This driver allow assessing at the same time ectopic gene activation in the flanks of the tail epidermis and gene inhibition at the midlines.”

Regulation

Gain of function

Publication

Roure et al. (2016). Msxb is a core component of the genetic circuitry specifying the dorsal and ventral neurogenic midlines in the ascidian embryo. Dev. Biol. 409(1):277-287