Name

FoxC>islet:WRPW

Targeted Gene

(ISL1; ISL2; LHX9)

Family

Sequence-based

Type

overexpression_construct

Supplier

n/a

Comment

The minimal promoter of FoxC (REG00001205) drives the expression of a repressive form of islet in the palps lineage. This constitutive repressor form consists in the DNA-binding domain fused to the WRPW repressor motif.

Regulation

Loss of function

Publication

Wagner et al. (2014). Islet is a key determinant of ascidian palp morphogenesis. Development 141(15):3084-92