Name

Fgf8>RGdeltaGAP

Targeted Gene

(DAB2IP; RASA1; RASAL2)

Family

Sequence-based

Type

overexpression_construct

Supplier

n/a

Comment

fgf8>RGΔGAP was generated by digesting fgf8>RasGAP with EcoRV, followed by religation, which results in removal of a large part of the GAP domain.

Regulation

Loss of function

Publication

Haupaix et al. (2013). p120RasGAP mediates ephrin/Eph-dependent attenuation of FGF/ERK signals during cell fate specification in ascidian embryos. Development 140(21):4347-52