Name

DEAB

Targeted Gene

(ALDH1A2; ALDH1A3; ALDH2)

Targeted Gene Group

(ALDH1A2; ALDH1A3; ALDH2)

Family

Sequence-based

Type

inhibitor

Supplier

n/a

Comment

Inhibitor of retinoic acid synthesis. Chemical name : 4-dimethylaminobenzaldehyde

Regulation

Loss of function

Publication

Pasini et al. (2012). Antagonizing retinoic acid and FGF/MAPK pathways control posterior body patterning in the invertebrate chordate Ciona intestinalis. PLoS ONE 7(9):e46193

Kanda et al. (2009). Epidermal expression of Hox1 is directly activated by retinoic acid in the Ciona intestinalis embryo. Dev. Biol. 335(2):454-63