- Transcript 'Cisavi.CG.ENS81.R41....' >
- Transcript 'Cisavi.CG.ENS81.R41....' >
- Transcript 'Harore.CG.MTP2014.S1...' >
- Transcript 'Boschl.CG.Botznik201...' >
- Transcript 'Phmamm.CG.MTP2014.S6...'
Transcript Model
Transcript Id
Phmamm.CG.MTP2014.S632.g10752.01.t
Possible name(s)
PIK3CA; PIK3CB; PIK3CD
Gene model
Location
S632 [43,103 / 60,481]
Amino acid sequence
Length: 977
>Phmamm.CG.MTP2014.S632.g10752.01.p
MAGYGYHGSAQYNMSRDEEIYDEWGYHDSVNVSVDFLLPTGIYIPLDVPRNDTIKQVKQL
LWEEAIHHPLFNQLQNQDSYTFVYITSTGIQEEITDERRHLSEFDLIHELPVLKLIQSQG
NIEEKRIIHEIHQLAGIKNENDLNVDAESRAFRKEMREEAIKVSIRRSSLHWKVLLENHY
PPTIIPHLNEKTHTRRDYGLIQLKYENTDNSYTIKVNPQWFTFDLISEAIQTWDQKAKSN
LPSTNPDDYVLKSDGKEFIVGNYQIYMFKCLRSAMVAKREKANLPPPQPPPILTMLHVAS
VRKLLPESHPGIQVQPGNYAPPVPDKRRQTCSLWQLDMQFSVRVLRAGNINANIENNKKD
NNQKNSMHNNATPIAYVNMTMFDFKANLKTGLYRLHCWLWPENVDSNNLHPRGGVTMNPD
TEQAPFLEILLPEYDRNPLVQYPPQEKVLEQAAFETSTSSSSIYPSPSKSHIAQLAAIVE
KDRFDDLFDNDKNLLWYLRLDCRENWPEALSKVLCAVKWNNYKNVALAQAMLGAWPPLEP
DRAMELLDGQFADEKVRDFAVRCLKQLRDDELQSYLMQLVQVLKFDSYLNSSLVRFLLER
AWNNRKIGHFLFWHLRAEITNTTLNLRFSLILEAYLYGNIPHMKMLYKQFDALNKMRALN
ERVKSQEFSQKDVKVRARKALQETANQESFAEALSYFEDPLEPNVLLGKPIFLVVTDLRQ
DMLTLQIISIMDMLWKADGLDLRMIPYGCLATGGISGMIEVVTESNTIANIQKSKTGKMH
SAFRHQTLFEWIEDKNPTKPELDQAIENFTYSCAGYCVATYVLGVGDRHSDNIMVREKGQ
LFHIDFGHILGNFKSKYGIKRERVPFVLAHDFVHVINKGKTNAKEEFQYFRKLCDRAFCI
LRKKGHLFITLFALMLHSGLPELTSLNHLEYLRETLALHLTEEKAIQQFRNKFNKALTDA
WSTSINWFFHNVAKDNK
Nucleotide sequence
Length: 2,934
>Phmamm.CG.MTP2014.S632.g10752.01.t
ATGGCTGGTTATGGATATCATGGGAGTGCTCAATATAATATGTCTAGAGATGAAGAAATC
TATGATGAATGGGGTTACCATGACTCCGTGAATGTCAGTGTGGACTTTCTTTTACCCACT
GGAATCTACATACCTTTAGACGTCCCCCGAAATGACACTATCAAACAAGTTAAACAGTTA
CTATGGGAGGAGGCAATTCACCACCCTTTGTTCAACCAACTTCAAAACCAAGATAGCTAC
ACATTTGTTTATATCACCAGTACTGGTATTCAAGAAGAGATTACTGATGAAAGAAGGCAT
CTTAGTGAGTTTGACCTTATTCATGAATTGCCAGTTCTGAAATTGATTCAGTCACAGGGA
AATATTGAAGAAAAGAGAATTATTCATGAGATACACCAGTTGGCTGGCATTAAAAATGAG
AATGATCTCAATGTTGATGCAGAGTCACGAGCATTCCGAAAAGAAATGAGAGAAGAAGCA
ATTAAAGTTTCAATACGGAGGAGTTCATTACATTGGAAGGTTCTTCTTGAGAACCACTAC
CCTCCTACTATCATTCCACATCTAAATGAAAAAACTCACACCCGAAGAGACTATGGTCTC
ATCCAGCTCAAATACGAGAACACAGATAACTCATACACTATCAAAGTCAACCCCCAATGG
TTCACATTTGACCTAATTAGTGAAGCAATTCAAACGTGGGACCAGAAAGCAAAGTCTAAC
CTTCCTTCCACTAATCCTGATGATTATGTGTTAAAGTCAGATGGAAAAGAATTCATTGTT
GGCAATTACCAAATTTACATGTTTAAGTGTCTTCGAAGCGCTATGGTTGCCAAAAGGGAA
AAAGCGAATTTACCCCCTCCCCAACCCCCGCCTATCCTCACAATGCTTCATGTCGCTTCG
GTGAGAAAATTACTACCAGAGAGCCACCCCGGAATTCAAGTCCAACCAGGGAACTACGCT
CCTCCCGTGCCTGACAAACGTCGTCAAACCTGCTCGTTGTGGCAGCTTGACATGCAGTTC
AGTGTGAGAGTTCTTAGAGCTGGAAACATCAACGCCAACATCGAAAACAACAAAAAGGAT
AACAACCAGAAAAATTCTATGCACAACAATGCAACTCCTATTGCTTACGTCAACATGACA
ATGTTTGATTTCAAAGCCAATCTCAAAACAGGCTTGTACCGTTTACACTGTTGGTTGTGG
CCTGAAAACGTTGATTCCAACAATCTTCATCCGCGAGGAGGCGTTACAATGAATCCCGAC
ACAGAACAAGCTCCTTTCCTGGAAATACTGTTGCCCGAATATGACAGAAATCCGCTGGTT
CAGTATCCTCCACAAGAAAAGGTTTTGGAACAGGCCGCATTTGAAACTTCGACAAGCTCC
AGTTCAATTTATCCAAGTCCTTCAAAATCGCACATTGCTCAACTTGCCGCAATCGTGGAG
AAAGATCGGTTTGATGATCTCTTCGACAACGACAAGAATTTGTTGTGGTATCTCCGCTTG
GATTGTAGGGAGAATTGGCCTGAAGCTTTGTCGAAAGTGCTGTGCGCAGTGAAGTGGAAC
AACTACAAGAATGTGGCACTGGCACAAGCGATGTTGGGTGCATGGCCTCCATTGGAACCA
GACAGAGCTATGGAACTTCTGGATGGTCAGTTCGCTGATGAAAAAGTCCGCGATTTTGCT
GTGCGATGTCTCAAACAATTAAGAGACGATGAATTGCAGAGTTATCTGATGCAACTTGTC
CAAGTTCTCAAGTTCGACTCGTATTTGAACAGCAGTCTTGTTCGGTTCCTGCTTGAGAGA
GCTTGGAACAATAGAAAGATTGGACATTTCTTGTTCTGGCATCTCAGGGCCGAGATTACC
AACACTACCCTCAACCTACGTTTCTCCCTTATACTGGAAGCTTATTTATACGGAAACATA
CCACATATGAAGATGTTGTACAAACAGTTTGACGCTCTAAACAAGATGAGAGCACTGAAC
GAAAGAGTGAAAAGTCAGGAGTTTAGTCAAAAAGACGTAAAAGTTCGTGCGAGAAAAGCT
TTACAGGAAACAGCAAACCAGGAATCGTTTGCTGAAGCTTTAAGTTATTTCGAAGATCCT
CTTGAACCGAATGTTCTTCTCGGCAAACCTATTTTCCTTGTTGTAACAGATTTACGTCAA
GATATGCTGACGCTTCAAATTATTTCCATCATGGATATGTTGTGGAAAGCTGATGGACTT
GACCTTCGCATGATACCATATGGTTGCCTAGCGACCGGCGGAATATCTGGAATGATCGAG
GTTGTGACAGAATCCAACACGATAGCAAATATTCAGAAGAGCAAGACGGGAAAAATGCAT
TCGGCGTTTCGTCATCAAACTTTATTCGAGTGGATTGAAGACAAAAATCCAACGAAACCA
GAGTTGGACCAGGCAATTGAGAACTTCACTTATTCTTGTGCTGGATATTGTGTAGCGACT
TATGTGTTGGGGGTTGGAGACCGACACTCTGACAATATTATGGTCAGAGAAAAAGGACAG
CTCTTTCACATCGATTTCGGTCACATTCTCGGTAACTTTAAGTCGAAATACGGGATCAAA
CGGGAGAGGGTTCCTTTCGTTCTTGCCCACGACTTTGTCCACGTCATAAACAAAGGGAAG
ACAAATGCAAAGGAGGAATTTCAATATTTCAGAAAGTTGTGCGACCGTGCCTTTTGCATT
CTGAGGAAAAAGGGGCATCTCTTCATTACTTTGTTCGCACTTATGCTTCACTCTGGACTT
CCCGAGCTTACGTCACTGAACCACTTGGAGTATTTGCGTGAAACATTAGCTCTTCATCTC
ACAGAAGAAAAAGCGATTCAACAATTTCGCAACAAGTTCAACAAAGCTTTAACCGACGCC
TGGTCAACATCAATTAACTGGTTCTTCCACAACGTCGCAAAAGACAACAAATAA
| PANTHER |
PI_Kinase (IPR015433) - T[22-353] 2.1E-267 - T[352-708] 2.1E-267 - T[711-977] 2.1E-267 |
| ProSiteProfiles |
PI3K_adapt-bd_dom (IPR003113) - T[28-119] 31.759 |
| SMART |
PI3K_adapt-bd_dom (IPR003113) - T[43-122] 2.3E-16 |
| Pfam |
PI3K_adapt-bd_dom (IPR003113) - T[44-121] 3.2E-22 |
| SUPERFAMILY |
Ubiquitin-like_domsf (IPR029071) - T[121-278] 2.76E-9 |
| Pfam |
PI3K_Ras-bd_dom (IPR000341) - T[200-279] 9.6E-7 |
| Gene3D |
C2_domain_sf (IPR035892) - T[346-440] 2.3E-17 |
| PIRSF |
PI3K_Vps34 (IPR008290) - T[355-442] 220.0 - T[445-590] 9.3E-17 - T[586-712] 3.2E-6 - T[708-974] 1.0E-56 |
| ProSiteProfiles |
PInositide-3_kin_accessory_dom (IPR001263) - T[461-638] 34.211 |
| SMART |
PInositide-3_kin_accessory_dom (IPR001263) - T[462-648] 5.1E-63 |
| SUPERFAMILY |
ARM-type_fold (IPR016024) - T[462-638] 1.67E-51 |
| Pfam |
PInositide-3_kin_accessory_dom (IPR001263) - T[469-645] 3.9E-51 |
| SUPERFAMILY |
Kinase-like_dom_sf (IPR011009) - T[643-968] 5.31E-78 |
| ProSiteProfiles |
PI3/4_kinase_cat_dom (IPR000403) - T[708-963] 63.73 |
| SMART |
PI3/4_kinase_cat_dom (IPR000403) - T[711-975] 1.1E-103 |
| Pfam |
PI3/4_kinase_cat_dom (IPR000403) - T[711-924] 1.6E-49 |
| Gene3D |
PI3/4_kinase_cat_sf (IPR036940) - T[764-977] 3.1E-80 |
| ProSitePatterns |
PI3/4_kinase_CS (IPR018936) - T[812-832] . |
| Protein Name | Identity | Bit Score | e-value |
|---|---|---|---|
| PK3CB_HUMAN | 48.742 % | 614 | 0 |
| PK3CD_HUMAN | 40.037 % | 713 | 0 |
| PK3CA_HUMAN | 35.13 % | 528 | 2.06E-171 |