- Transcript 'Harore.CG.MTP2014.S2...' >
- Transcript 'Cisavi.CG.ENS81.R1.5...' >
- Transcript 'Cisavi.CG.ENS81.R27....' >
- Transcript 'Haaura.CG.MTP2014.S8...' >
- Transcript 'Harore.CG.MTP2014.S1...'
Transcript Model
Transcript Id
Harore.CG.MTP2014.S128.g03896.01.t
Possible name(s)
ALK; LTK; ROS1
Gene model
Location
S128 [214,164 / 231,345]
Amino acid sequence
Length: 766
>Harore.CG.MTP2014.S128.g03896.01.p
MRYACIILLLKNNKTSSSVLSIVTDNSYIYWLSPSRSVVKFLDLSSSTYAVDDITLSPEI
VNQDKHGVRAACRIPSYVPIVPYPTTVSGSFLSFNLTGINATQYDWFTSPICIQEANPDI
TFAFLYVKRTNSISLDGIPQICFGSSECIYEPVSSDEDLDAVQLNNLSPDSEYVIHLMVY
SETLNHKSTVISPGRVLRTSCGVSSPVTNLTCSGIDSNKLQVLWNEPIQKNSAEIRYEVY
INDTIQLNAFYVGEDGSGNLIHNTRQNDVSYFTVRTFPLNCSFSSGQYSSSVSIPCRSFL
PPVQPFVVSVSSMRVTLNWTAPADNSVQYLIIEWSLAILNGQNTRSWSKSEMLDGSRSIT
YAVTDLVPYTGYTFRVHQQYAGFTGNEGWHYSASVSTMTSPDIPSFPLDVAVEREADIFY
LTWTPPKSNGADLLEYVIEYRNRSSPNASRILYNAWKIAANRSASFTRYRLTNLIEDIWY
EFRVSALNAVGLGDKSEPSSPFSCRRCGKESTKSHGQSQSEITTIHLSYGADLQLAQIRH
MAELASWRGVPNLPQDYMDLLPVFPREKLTLTDFLGKGAFGEVYKGVALLEEGEKGVAVK
TLREGSTDSEKCEFLMEAYFMSNFDHENILSLLGVCLDNEPQYLILELMDGGDLLHYLRD
ARPNPIMSAKLTTEDLLAICLDVAAGCKYLNEQHFIHRDLAARNCLVSTKSYQTTSRIVK
IGDFGLARDIYRNDYYHKAGEGLLPVRWMAPESLVDNIYTAHSDIW
Nucleotide sequence
Length: 3,564
>Harore.CG.MTP2014.S128.g03896.01.t
AGATATACTATAACATCGTACATGCTAATGCGTGATGCATTTGAACTGTAAAGTATCGGT
ACACGGAATTCATCATTCTCATGATGATAAAGATACTCGACCACTGGAAATATGAGTATT
GGTCTTTGCTACTTGTCATACTACTGTTCCTCACACGATCACATGGAAATTTGGTTGTAG
AAAATGCCCAGGTTTTGAGAGCGGATTCTGTTCGCCCACATCTACTTCTTCCACCACAAC
TGCCTGATTATCCACTGATTCGTGCGAAACGGGAAACATCATTTTCCTACTCCAATGTCC
TTGACTTTTTCAACAATTGCAGTTCCGATCCGAGTTGTTCAGAACTGAGCAATGTGACGA
GTCACTCCGTTAAGAGTGAAAATTCAATTTTTGTCTCGACTCTGCGAAGAATTATCAAGA
CCGAAATAAGCAACAGCAGTAAGTCCTGCGTTTGTACCGTCCTGTACAACACAACAAACG
AAGATGAGATATGCATGCATTATTTTATTATTGAAAAATAATAAAACTTCCTCTTCAGTT
CTTTCTATTGTAACGGACAATTCCTACATATATTGGCTGAGCCCATCACGGTCCGTCGTA
AAGTTTCTTGACCTCAGCTCATCCACTTATGCCGTTGACGACATTACTTTATCACCCGAA
ATAGTAAATCAAGATAAGCACGGAGTCCGTGCTGCCTGTAGAATTCCATCCTATGTTCCT
ATCGTCCCTTATCCTACAACGGTTTCTGGAAGCTTCTTGAGCTTCAACTTGACCGGTATC
AATGCTACTCAATACGACTGGTTCACTTCCCCGATATGTATTCAAGAAGCAAATCCAGAT
ATAACCTTTGCTTTTCTTTACGTCAAGCGTACGAATTCGATTTCTCTCGATGGCATACCT
CAAATATGTTTCGGTAGTTCCGAATGCATTTACGAGCCTGTCAGTTCTGACGAAGATCTG
GATGCTGTTCAACTGAATAATCTCTCACCAGATTCAGAGTACGTCATACATCTAATGGTG
TATAGTGAGACGCTCAATCACAAATCAACAGTTATTTCTCCTGGAAGGGTATTAAGAACT
TCCTGCGGAGTGTCATCACCTGTCACAAACTTGACTTGTTCGGGAATAGACTCCAATAAA
CTGCAAGTCCTGTGGAATGAACCAATCCAGAAAAATTCGGCTGAGATCAGATACGAAGTG
TACATAAATGATACGATTCAATTGAATGCTTTTTATGTTGGTGAAGATGGCAGTGGCAAT
CTCATTCATAACACCAGACAAAATGATGTCTCATATTTTACGGTACGCACTTTTCCTCTC
AACTGTTCCTTTTCGTCTGGTCAGTACAGCTCTTCTGTTTCCATTCCATGTCGCTCTTTC
TTGCCACCAGTCCAACCCTTTGTGGTTAGCGTGTCATCGATGCGAGTTACGCTAAATTGG
ACAGCTCCAGCAGACAACAGCGTTCAATATCTCATCATTGAATGGTCATTGGCTATTCTG
AACGGACAAAATACTAGAAGTTGGAGCAAGAGCGAAATGCTGGACGGAAGTCGTTCAATC
ACGTATGCTGTCACGGATTTGGTCCCGTACACAGGATACACTTTCAGGGTTCATCAGCAA
TATGCTGGCTTTACTGGTAATGAAGGATGGCACTACTCTGCATCAGTAAGCACAATGACA
AGCCCTGATATTCCAAGCTTTCCTCTCGATGTTGCAGTGGAAAGAGAGGCTGATATATTT
TATCTTACTTGGACGCCACCCAAGTCGAATGGTGCTGATTTGCTGGAATATGTTATTGAG
TACAGAAATCGATCTTCACCAAATGCCAGTCGAATTCTGTATAATGCGTGGAAAATTGCT
GCTAACAGAAGTGCCTCTTTCACCAGATACAGGCTGACAAATTTAATTGAAGATATTTGG
TATGAATTCAGGGTTTCTGCTCTCAATGCTGTTGGACTCGGGGACAAGAGTGAACCGTCT
TCTCCATTTTCCTGCAGGAGATGTGGTAAAGAATCAACTAAAAGTCATGGACAGTCTCAG
TCAGAAATTACAACAATACATCTCAGCTATGGTGCCGACTTGCAGCTTGCACAGATCCGT
CACATGGCTGAACTAGCTAGCTGGAGAGGAGTGCCGAACCTTCCTCAAGACTATATGGAT
TTGTTACCTGTGTTCCCTAGAGAAAAATTAACTCTGACGGACTTCCTTGGCAAGGGAGCT
TTCGGAGAAGTGTACAAAGGAGTGGCTCTGCTAGAAGAGGGCGAAAAGGGCGTTGCAGTT
AAAACCCTGCGCGAAGGGTCAACTGACAGTGAGAAATGCGAATTTTTAATGGAAGCTTAT
TTCATGAGCAATTTCGATCACGAAAATATACTTTCACTGCTCGGAGTGTGTTTGGACAAT
GAACCTCAGTATCTCATTCTAGAACTAATGGATGGTGGGGACCTACTTCACTACTTGAGA
GATGCTCGCCCGAATCCTATCATGAGTGCCAAACTTACAACAGAAGATTTACTCGCTATA
TGTTTGGATGTTGCAGCTGGTTGCAAGTACCTGAATGAGCAACATTTCATTCATAGAGAT
TTGGCTGCCAGAAACTGTTTGGTTTCAACAAAATCCTATCAGACCACATCGAGGATAGTG
AAGATTGGTGATTTTGGTCTGGCTCGTGACATATACAGAAATGATTACTATCATAAGGCT
GGGGAAGGCTTATTACCTGTCCGCTGGATGGCACCAGAGAGTCTAGTTGACAATATCTAC
ACTGCTCACAGCGATATCTGGTGAGTGGCAGTTACTGATCCAATTTTTAATCTTAGTGTT
CATTTTTTAAAGTTTTTATTATCAATAATTGATCACGGAACATATGTTGTTCTATATGAA
ACTTATCTCTAGTTATCATAACATGGAGTGCAGATTGGAGTTCAGGACTTGTATACTTGC
ACTTCAAGTCATATCCCTGCTTAAAAACCACTGTCTGTTTCATGAATAGTAGCATTGCCA
TTCTTGAGAAATAATAATGCTACAAGCAGTTGCCAAGTGAGATTTCAGGCTGTATCGGGC
GAATTTTAAAAAACTTTCCGGAAGTCTAAAGGTAAATTTGACAAAATATTTAACCATATA
ATATCATTGCCAACCCCAAAGGCTTGGGTCTTTTCCCTTTTGCCCATTACTATGCTACTG
ATAATAACTTCAGTTTTCATAGAATGTTGTATTGCTTGGCATGAACAGAGTAAGGTTACA
GAGTTACAAATAGCTTAGTTTATGGTATAGTATAGGTAACAGTTTATGAATTTAGGTAAT
CAGTGCAATCAATACAGGATTAAGGGAATAAAATAAAATAATAATAAAATGGTAATATTT
GGAATTTTTGGCTGGTAAATTGTAGCGGTTACAGATTCTACTCCCTATAGTATATCTCTC
CATTGATCTCTAGATGTCTTTTAGATTACTTCAATAAATATGTTGTCCAACACACTTTTG
ATAGATGTTAAACCCTAAAAGACACATGTGACATTGCATAAAATACCATTGAGGAGCTGA
ACTTTTTAATGCTTTTCCTGGTTG
| SUPERFAMILY |
FN3_sf (IPR036116) - T[161-243] 8.3E-9 - T[301-501] 2.42E-28 |
| SMART |
FN3_dom (IPR003961) - T[204-284] 150.0 - T[299-385] 2.7E-4 - T[404-493] 9.6E-9 |
| ProSiteProfiles |
FN3_dom (IPR003961) - T[206-299] 8.363 - T[301-402] 14.115 - T[404-507] 17.152 |
| Gene3D |
Ig-like_fold (IPR013783) - T[300-386] 1.8E-9 - T[387-507] 3.6E-19 |
| Pfam |
FN3_dom (IPR003961) - T[301-385] 1.9E-7 - T[415-496] 2.8E-10 |
| CDD |
FN3_dom (IPR003961) - T[301-376] 2.21964E-6 - T[404-500] 3.77244E-15 |
| SUPERFAMILY |
Kinase-like_dom_sf (IPR011009) - T[552-766] 1.39E-54 |
| ProSiteProfiles |
Prot_kinase_dom (IPR000719) - T[569-766] 32.541 |
| SMART |
Tyr_kinase_cat_dom (IPR020635) - T[569-766] 4.0E-56 |
| Pfam |
Ser-Thr/Tyr_kinase_cat_dom (IPR001245) - T[570-766] 4.3E-63 |
| ProSitePatterns |
Protein_kinase_ATP_BS (IPR017441) - T[575-600] . |
| PRINTS |
Ser-Thr/Tyr_kinase_cat_dom (IPR001245) - T[646-659] 1.0E-15 - T[689-707] 1.0E-15 - T[744-754] 1.0E-15 - T[763-766] 1.0E-15 |
| ProSitePatterns |
Tyr_kinase_AS (IPR008266) - T[695-707] . |
| Protein Name | Identity | Bit Score | e-value |
|---|---|---|---|
| ROS1_HUMAN | 35.94 % | 320 | 1.43E-93 |
| ALK_HUMAN | 48.293 % | 212 | 3.66E-57 |
| LTK_HUMAN | 47.264 % | 199 | 8.03E-54 |