- Transcript 'Phfumi.CG.MTP2014.S7...' >
- Transcript 'Phfumi.CG.MTP2014.S9...' >
- Transcript 'Moocci.CG.ELv1_2.S54...' >
- Transcript 'Moocul.CG.ELv1_2.S11...' >
- Transcript 'Boschl.CG.Botznik201...'
Transcript Model
Transcript Id
Boschl.CG.Botznik2013.chr9.g47828.01.t
Possible name(s)
ALK; LTK; ROS1
Gene model
Location
chr9 [8,514,372 / 8,522,869]
Amino acid sequence
Length: 459
>Boschl.CG.Botznik2013.chr9.g47828.01.p
MSTLFFILQERNIESCIRRVSSRNQVGEGDRSPPSNLIFYHKEIEVSDSYEAIGISAGAL
VFLVSMVAAILVWRCQYQKYGHTDSTAEATDVNVDDNPKTGDSQNSSVAHVNETSASSNL
LPPSNLPLVPREKLELLEFLGKGAFGEVYAGVAYDVGEDPGSSTRVAVKLLRENSGQKKE
FLMEANVMSKFDHKNILSLLGVCWESQHQYLVMELMEGGDLSHYLRDAKPTAITLAKLST
LDLIDICLDIAAGCRYLEEQHFIHRDLAARNCLVSTKDYSSDSRVVKIGDFGLARDIYRS
EYYHKHGEGLLPIRWMAPESLEENLYTTQSDVWAFGILLWEVMSYGRRPYQILTDIEVLP
FIKAGGRMEKPDNCPEPIAPTFRPSFAWTLEFLHNVKDACDGMCDDDSDMAPGNYMTATT
SDEDFADEGIRESRSSSLDSRGRYNAAFDTDEDSGSDVD
Nucleotide sequence
Length: 1,380
>Boschl.CG.Botznik2013.chr9.g47828.01.t
GATGTCAACACTATTTTTTATTTTGCAGGAACGAAACATCGAAAGCTGCATTCGGAGGGT
GTCATCAAGAAATCAAGTGGGTGAAGGTGATAGGAGTCCGCCATCGAATTTGATTTTCTA
TCACAAAGAAATCGAGGTGTCAGATTCCTATGAAGCCATTGGAATTTCCGCTGGTGCATT
GGTATTTCTGGTTTCCATGGTTGCTGCAATATTGGTGTGGCGCTGCCAATATCAAAAGTA
TGGTCACACTGACTCAACTGCTGAGGCTACTGATGTAAATGTTGACGACAATCCAAAAAC
CGGGGACTCCCAAAACTCGTCAGTCGCACACGTCAATGAAACCTCTGCTTCGTCAAACCT
GTTACCGCCATCAAATTTGCCACTTGTGCCAAGGGAGAAATTGGAGCTTCTGGAATTCCT
AGGCAAAGGGGCGTTTGGTGAGGTTTACGCAGGTGTCGCATATGACGTTGGGGAGGATCC
AGGGTCTTCCACAAGAGTTGCTGTGAAGCTATTGCGAGAAAACTCCGGCCAGAAAAAAGA
GTTTTTAATGGAGGCCAACGTTATGAGTAAATTCGACCACAAGAACATCCTGTCACTCCT
TGGGGTGTGTTGGGAGAGTCAGCATCAGTACTTAGTGATGGAGCTTATGGAAGGCGGGGA
TTTGTCTCATTATCTTAGGGACGCGAAACCCACTGCGATTACACTTGCCAAGTTATCGAC
ACTTGACCTCATTGATATTTGTCTGGATATCGCCGCCGGGTGTAGGTATCTGGAGGAACA
GCATTTCATTCACAGAGACCTGGCCGCGCGTAATTGTCTGGTATCAACCAAAGACTATTC
CTCCGACAGCAGAGTGGTGAAAATCGGCGATTTCGGATTGGCCCGCGACATTTATCGATC
CGAATACTACCACAAACATGGAGAAGGACTCCTTCCAATTCGGTGGATGGCGCCTGAATC
TTTAGAAGAGAATCTCTACACGACACAAAGCGATGTTTGGGCATTCGGTATTTTGCTTTG
GGAAGTCATGAGCTATGGTCGGCGGCCGTATCAAATTTTGACGGACATAGAGGTTCTACC
GTTCATAAAAGCAGGCGGCCGAATGGAAAAACCAGACAATTGCCCGGAACCAAGCGCGCC
CACGTTTCGGCCGTCGTTCGCTTGGACTTTGGAATTTTTGCATAATGTCAAGGATGCTTG
CGATGGAATGTGTGACGATGATTCTGACATGGCTCCTGGAAATTACATGACCGCCACCAC
CTCGGACGAAGATTTTGCTGATGAAGGCATTCGAGAGTCGCGATCTTCATCACTTGACTC
TAGAGGGCGCTATAACGCAGCATTCGATACGGATGAAGATAGCGGTAGTGATGTGGATTG
| SUPERFAMILY |
Kinase-like_dom_sf (IPR011009) - T[112-390] 7.24E-71 |
| Pfam |
Ser-Thr/Tyr_kinase_cat_dom (IPR001245) - T[134-379] 4.2E-83 |
| ProSiteProfiles |
Prot_kinase_dom (IPR000719) - T[134-459] 36.796 |
| SMART |
Tyr_kinase_cat_dom (IPR020635) - T[134-393] 2.2E-121 |
| ProSitePatterns |
Protein_kinase_ATP_BS (IPR017441) - T[140-169] . |
| PRINTS |
Ser-Thr/Tyr_kinase_cat_dom (IPR001245) - T[213-226] 4.6E-26 - T[256-274] 4.6E-26 - T[311-321] 4.6E-26 - T[330-352] 4.6E-26 |
| ProSitePatterns |
Tyr_kinase_AS (IPR008266) - T[262-274] . |
| Protein Name | Identity | Bit Score | e-value |
|---|---|---|---|
| ROS1_HUMAN | 45.383 % | 312 | 1.68E-94 |
| ALK_HUMAN | 47.5 % | 271 | 2.16E-80 |
| LTK_HUMAN | 38.992 % | 253 | 6.66E-76 |