- Transcript 'Phmamm.CG.MTP2014.S3...' >
- Transcript 'KH2012:KH.L154.1.v2....'
Transcript Model
Transcript Id
KH2012:KH.L154.1.v2.R.SL2-1
Possible name(s)
LRP5; LRP6
Gene model
Location
KhL154 [337,861 / 372,434]
Amino acid sequence
Length: 1,824
>KH.L154.1.v2.R.SL2-1
YKMKLLFISFLYFLSSNASKDTALNAPFLLLANHVDIRLIPSGEPNNTVIVASDLKGALA
CDFFFEEQHIYWIDCLNGRIQYVDMTTPQRKKMDVLVSGMVKPEGLACDWIGRKLYWTDR
GTKRIEVSELDGSHRKVLLWNNLDLPRAIAVDPHNRYMYWTDWGEEPKIERSGMDGSQRE
VLINQNIYWPNGITLDYEEGKVYWIEAGHHFIHRINLDGSQSDQSRSSNSTSTNIPLSSE
EGGEWVGALEHPYAITLFRDRVYWSDWRTSSLYSISKNQTEVPRLVKGDILSPMDLQAYN
SQRQKPGPNPCGSTNGGCSHLCLLSPKPPYYKCACPTGVQIMKDRKTCKHGPDQILLLAR
RTDIRMISLDTDDHTDVLLPVKTVLNAVTVDYDPVDKFVYWTDEDRKAILRCHLNGTGSE
AIITENLEQSDGMAIDWVARNLYWTDTGRNYVAVARLNGTSRRILIETEIDEPRAIVVDP
TAGYFYWTDWGENPKIERVEMDGTNRILFVRKHLKWPNGLAIDHTHGWLYWADASLDKIE
RIKLDGTQRKMLVSGKIPHIFGFSILGNYLYWADWQRRRIERMRIGDPRSREILIDQLPN
LMGVKATGMTPLPGTNPCARNNGGCSHLCLYTPEGPRCSCPTGLELAINSHQCVVPEAYL
LYSLPKVGGIKEISLDTAQNDKSLPFNKPVEAYLLDFSVDDSMVYWTNTRDMTISRAFMN
GSNVERFIDIGIEILQGVAVDWIGRNVFWADAQANRIEVARMDGTSRRPIIWQGLDSPAC
IAMDPANGYIYWSEWGTDTCIKRANLDGSNVVRLTQIGDVGRASSLTIDYEDRRIYWVDY
DSNMIMSSDMEGRYLINVADEPGNVISSLTLYGEHVYWADSKQKTIQRANKLHGASRRII
ETGLGSIDDMLVFHASRQIGVTSCSRDNGGCQYLCLSLPGGNYTCECPAHYTLNLLDNSS
CVAPLNFLLVSQTSYISRIVFESSEGNAKPTPDAVLPIKGLKDACSIDYDPIERTIYWID
CATGEIKSCRDNGTDARVLVANRGSNGSNRPHDLAVEPYTRHLYWTDSLSNSIQMMNLNG
TMIGTVLSGKLNAQGVGNGKYIDIMPRKITIDSMKGRIYFSNTCHDTKSCRFKILQSALD
GSDCIELFSHNLHNVSAMVVDSQSKRLYWSDPDREVIEWSNTDGSHRTTLIENSISQPVG
LAVFGDSIYWVDSQVHILTNKIDGSNRRIIQSRVRNLKAIAAAKLINLGDRLQHPCFTDN
GGCSHICVPQVTGVTRCSCPTHLAVIEDSKCGKPVTCGPGYFRCKTLSICIPMNWKCDSE
NDCEDASDEMNCETNRLPCKDYEVECKAVLPQCVNQSKICDGTYDCISQSDEMNCAFSLD
CGPNLKVCPSGQCVAVGSSCDCTNCQPIIGGNDQDNSMVIVIGIVCGCVVLLGIGLFIRH
CMTHNSRYPQGVVMFAPHTNGNCTVNVEIQSRADTTEVVNHQKTNGNQSRKKGSTKGKAS
INLSFHPSGSRSGSNSRFGVPSNWQFPVHYTKDCHSMDRPCVPGASRCSSIQAKVFSPTT
NPPPSPATVRSGSKSGDRVYSTDSGRSHHRCKNGYKHRRSQHRYPIHHPPPPTPCNTDTC
DDVDRGYRHGGSNRSPPSTNSSVPHEPPPPYHHHQCCYHCYHQYPPQCRHPDGSSSSSYQ
CEDDDCSCGGDSLPSYPPSYNQRGRSWRRPPHRSYLSSDLNSDSDPFAPPPTPRSQYMSE
CCYTHGETTEADDPLDEEDETVDDDVTNDVTENLIAGSGVTEDEEGGSEDDADTVLLNPR
SSPSVTERSFRIYNPPPSPATDSS
Nucleotide sequence
Length: 6,565
>KH2012:KH.L154.1.v2.R.SL2-1
GCTGTTAAGTTAAAGCTGTATGATGTGTTAAGGAGGCGCACACTATGACATTGGATTTTA
TTTTACACGTTAAACGACGGAAAAGGGATTTTAATGAGAGAGAATAACATTTAATATAAA
ATGAAGCTGCTTTTTATTTCTTTTTTATACTTTTTATCATCAAATGCAAGTAAAGATACT
GCTCTCAACGCCCCTTTTTTATTGCTCGCAAATCATGTTGATATTCGATTAATTCCATCT
GGTGAGCCCAACAACACAGTTATCGTGGCTTCAGACTTAAAAGGAGCATTAGCCTGTGAT
TTCTTCTTTGAGGAACAGCATATCTACTGGATTGACTGTCTTAATGGAAGGATCCAGTAC
GTTGACATGACGACCCCACAGCGCAAAAAAATGGACGTACTTGTTTCGGGTATGGTTAAA
CCTGAAGGCCTCGCATGCGACTGGATCGGTCGAAAACTGTACTGGACAGACCGTGGAACA
AAAAGAATTGAAGTTAGTGAATTAGATGGAAGTCACAGGAAAGTTTTACTGTGGAACAAT
CTAGACCTTCCGAGAGCTATAGCAGTGGATCCTCATAACAGGTACATGTACTGGACAGAC
TGGGGCGAAGAGCCGAAGATAGAACGTTCTGGAATGGATGGTTCACAGAGAGAAGTTCTG
ATCAACCAGAATATTTACTGGCCTAATGGAATCACACTTGATTATGAAGAAGGGAAAGTT
TACTGGATCGAAGCTGGCCATCATTTTATTCATCGTATTAACTTAGATGGCTCACAGAGC
GATCAGAGTCGCTCCTCTAACTCTACATCCACGAACATCCCTCTCTCCTCCGAGGAGGGA
GGAGAGTGGGTGGGAGCTCTGGAGCATCCCTACGCGATCACTCTCTTCCGGGATCGAGTT
TACTGGTCCGATTGGAGGACCTCATCTCTTTATTCCATCTCGAAAAATCAAACCGAGGTT
CCTCGTTTAGTGAAAGGGGACATCCTGTCGCCAATGGACCTACAGGCCTATAACTCGCAG
AGGCAAAAACCAGGTCCTAATCCGTGTGGTTCCACGAATGGTGGATGCTCACACTTATGT
CTCCTCTCACCCAAGCCCCCATATTACAAGTGTGCGTGCCCGACCGGGGTCCAAATCATG
AAGGACCGAAAAACATGTAAACACGGTCCAGACCAGATCCTTCTGCTTGCACGAAGAACA
GACATTCGAATGATTTCGCTCGACACTGATGACCATACGGATGTACTACTGCCTGTAAAG
ACAGTGCTGAATGCAGTCACAGTGGATTACGACCCAGTGGATAAGTTTGTGTACTGGACG
GATGAAGACAGAAAAGCAATTCTCAGATGTCATCTTAACGGCACAGGTTCTGAAGCAATT
ATCACAGAAAACTTGGAGCAGTCGGATGGCATGGCAATAGATTGGGTTGCAAGGAACTTG
TATTGGACAGATACGGGTAGAAACTATGTAGCAGTGGCACGGCTTAATGGGACATCCCGG
AGAATTCTTATCGAAACTGAGATTGACGAACCAAGAGCAATCGTGGTCGATCCAACTGCT
GGCTATTTCTACTGGACCGACTGGGGAGAAAACCCCAAGATAGAACGTGTCGAAATGGAC
GGCACAAACAGAATTTTGTTCGTAAGAAAACACCTAAAATGGCCAAACGGTTTAGCAATT
GACCACACCCATGGCTGGCTGTATTGGGCCGACGCATCGCTCGATAAAATTGAGCGGATC
AAGCTTGACGGGACACAGAGGAAGATGTTGGTGTCCGGGAAGATACCACACATATTTGGA
TTCAGCATTCTTGGCAACTATCTCTACTGGGCTGACTGGCAAAGAAGAAGAATTGAACGA
ATGCGAATTGGTGATCCGAGATCCAGGGAAATACTCATAGATCAACTTCCTAACCTAATG
GGGGTGAAGGCCACTGGTATGACACCTTTACCAGGAACTAATCCTTGTGCAAGAAATAAC
GGGGGTTGCTCACATTTGTGTCTATATACACCAGAGGGTCCGAGGTGCAGTTGCCCAACT
GGTCTCGAATTAGCGATCAACAGTCACCAGTGCGTGGTACCTGAAGCTTACCTTCTCTAT
TCACTACCAAAAGTTGGCGGAATTAAAGAGATTTCTCTCGACACTGCACAAAACGACAAG
TCCCTTCCATTCAACAAACCCGTTGAAGCTTACTTACTTGATTTCTCAGTAGATGATAGT
ATGGTGTATTGGACAAATACAAGAGACATGACAATCTCGCGTGCTTTTATGAACGGGTCC
AACGTTGAGAGATTCATAGATATCGGCATAGAGATCTTACAAGGGGTCGCGGTTGACTGG
ATCGGACGCAATGTGTTCTGGGCTGACGCTCAAGCCAATCGGATCGAAGTTGCTCGTATG
GACGGGACAAGCAGGCGACCAATCATATGGCAGGGATTGGATTCACCTGCGTGTATCGCC
ATGGATCCAGCCAATGGGTACATATACTGGTCAGAGTGGGGCACAGACACGTGCATAAAA
CGCGCAAATCTGGATGGTTCCAACGTGGTACGATTGACACAAATCGGGGACGTTGGACGC
GCTAGTTCCCTTACTATAGATTACGAGGATAGAAGGATTTATTGGGTGGATTATGACAGT
AATATGATCATGTCTTCCGATATGGAAGGTAGGTATTTAATCAATGTAGCTGACGAACCA
GGAAATGTTATTTCAAGTTTAACATTATATGGAGAACATGTGTATTGGGCAGATAGCAAA
CAGAAGACCATACAAAGAGCAAATAAATTGCACGGAGCGAGCAGGAGAATAATCGAGACT
GGTCTCGGTTCTATTGATGATATGTTGGTGTTTCACGCATCACGTCAAATCGGTGTCACA
TCATGTTCACGTGATAACGGGGGGTGCCAATACCTATGTTTAAGTCTTCCAGGGGGAAAC
TACACTTGCGAGTGCCCTGCCCATTACACGTTAAATCTATTGGATAATTCTTCATGTGTT
GCCCCATTAAATTTCCTATTGGTGAGCCAGACTTCATATATTTCCCGTATTGTGTTCGAA
TCCTCCGAAGGGAATGCAAAACCAACGCCTGACGCCGTGTTACCCATTAAAGGGCTGAAG
GATGCCTGCTCAATTGACTACGACCCAATAGAACGCACAATATACTGGATCGACTGCGCC
ACCGGTGAAATAAAGAGTTGCCGAGACAATGGCACAGATGCGAGAGTTCTCGTCGCAAAT
AGGGGTTCAAACGGGTCAAATCGACCCCATGATTTAGCTGTGGAACCCTACACAAGACAT
TTGTACTGGACAGACTCTCTGTCTAATTCCATCCAAATGATGAATTTAAATGGGACCATG
ATTGGGACTGTATTATCTGGTAAACTCAATGCACAAGGGGTGGGAAATGGAAAATACATT
GATATTATGCCAAGGAAAATTACAATAGACTCCATGAAAGGGCGCATATACTTCAGTAAC
ACATGCCATGACACAAAGTCATGCAGATTTAAGATTCTACAATCTGCTTTAGACGGATCT
GATTGCATTGAATTATTCAGTCATAATTTACACAACGTTTCAGCTATGGTAGTAGACTCA
CAATCTAAAAGATTATACTGGTCTGATCCGGATCGTGAGGTTATAGAATGGTCAAATACC
GATGGAAGCCATCGTACCACGCTTATTGAGAACAGTATAAGTCAACCAGTTGGTTTAGCT
GTGTTTGGTGATTCCATCTATTGGGTGGACTCTCAGGTTCATATTTTAACGAATAAAATC
GACGGTTCAAATCGACGAATTATTCAAAGTCGAGTCCGAAACTTAAAAGCGATCGCTGCA
GCCAAGCTTATCAATCTTGGTGACCGATTACAACACCCATGTTTCACTGATAATGGGGGT
TGTTCACATATCTGCGTGCCACAAGTTACCGGGGTGACACGGTGTTCGTGCCCCACACAT
CTTGCTGTGATAGAAGATTCCAAATGTGGCAAGCCAGTGACGTGTGGTCCAGGTTATTTT
CGATGCAAAACTTTATCGATTTGTATTCCCATGAATTGGAAATGTGACAGTGAGAATGAT
TGCGAAGATGCCTCAGATGAAATGAATTGTGAGACAAATAGACTGCCGTGTAAGGATTAC
GAAGTGGAATGCAAAGCAGTCTTGCCCCAGTGCGTCAACCAGTCAAAAATTTGCGACGGA
ACGTATGATTGCATCTCGCAAAGTGATGAAATGAATTGCGCGTTTTCTTTAGATTGTGGA
CCTAACCTAAAGGTGTGTCCATCTGGCCAGTGTGTGGCAGTAGGGAGCTCATGTGACTGC
ACCAACTGTCAGCCAATCATTGGCGGCAATGATCAAGACAACTCAATGGTTATAGTGATC
GGCATCGTATGTGGGTGCGTGGTTTTGCTCGGAATCGGTCTTTTTATACGACATTGCATG
ACCCACAACTCTCGTTACCCGCAAGGGGTTGTCATGTTCGCCCCGCACACGAACGGCAAC
TGCACCGTCAACGTAGAAATCCAGTCGCGTGCCGACACAACTGAAGTCGTAAACCACCAA
AAAACTAACGGCAACCAGAGCCGTAAAAAGGGGTCAACAAAGGGGAAAGCATCGATTAAC
CTTTCCTTTCACCCCAGCGGGAGTAGATCGGGGTCAAATTCCCGGTTTGGGGTCCCATCA
AATTGGCAATTTCCCGTCCATTATACAAAGGATTGCCATTCTATGGATCGTCCCTGTGTT
CCAGGGGCATCAAGGTGTTCAAGCATACAAGCCAAGGTTTTCTCACCGACCACCAACCCC
CCACCCTCCCCTGCAACAGTGAGATCGGGCTCCAAAAGCGGGGACAGGGTTTATTCAACT
GATTCTGGAAGGTCTCACCATAGATGTAAGAATGGATATAAACACAGAAGGTCTCAGCAC
CGCTACCCAATCCATCACCCTCCACCCCCTACCCCATGCAACACAGACACATGCGATGAC
GTAGACCGGGGTTACAGACACGGGGGTTCGAATCGAAGCCCCCCATCAACGAACTCAAGC
GTCCCGCATGAGCCCCCGCCCCCCTACCACCACCATCAGTGTTGTTACCACTGCTACCAT
CAATACCCCCCACAATGTAGACACCCAGATGGCAGCTCGTCAAGCTCGTACCAATGTGAG
GACGACGATTGCTCCTGTGGTGGTGACTCCCTACCATCTTACCCCCCCTCTTATAATCAG
CGGGGGCGCTCCTGGCGAAGACCTCCACATCGCTCCTACCTCTCATCGGATCTGAATTCG
GATTCGGATCCATTCGCGCCCCCGCCAACCCCACGCAGCCAGTACATGTCGGAATGTTGT
TACACCCACGGTGAAACGACGGAGGCCGACGATCCATTAGACGAAGAAGATGAGACGGTT
GATGATGATGTCACTAATGACGTCACAGAAAACCTCATTGCAGGATCGGGAGTCACGGAA
GATGAGGAGGGAGGATCTGAAGATGATGCGGACACAGTTTTACTCAATCCGAGGTCATCC
CCATCAGTAACGGAGCGAAGTTTTCGCATCTATAACCCTCCGCCATCCCCAGCCACAGAT
TCCTCATGAAGCAGTGCTGCCAGTTGAAAAACTTAATACAAAAAATAGTGCTCCCAGTTA
AAAACCTCTGCACAAAAGGCAGTGCTGCCAGTTGAAAAACTCGGTACAAAAAACAGTGCT
GTCAGTTGAAAAACTTGTCACAAAAAGCAGTGCTACCAGTTGAAAAACTTGTCATAAAAA
GCAGTGCTCCCAGTTAAAAAACTTGACACAAAAAACAGTACTACCAGTTGAAAAACTTGT
CACAAAAGCAGTGCTCCCAGTTAAATAACTCCTCACAAAAAACAGTGCTACCAGTTAAAA
GGTCAGAAAATGCCAGGCGAATAACTAAAACATGATCGAACAGCACTGCAGAAACATGTA
TATAAATCCAATTCCCTATTGTAATGGGAATGTTTAATGTTTTTACCATTTTTTGTTTTA
TTTCATTTCAAAACCAATAGAACCCTCTGCCAACGCTGTCGTTGCCAACTTTTTTGCATT
TTATTCTTTTTTTTGTTTGTTATCAAATTTTCAGCGGTACACGAAACTTTGCATTTGATC
TTGTATATACTGCACTTCAATTCTTCCGAACGAATCATGTTTTTTTTATTGTACAGTATA
AACATTAAGTTTGTCTGTCGTTCTGGTCAACTATCTTGACAAAATAATCGCATAAACGTT
TTAGGATTTTCAGGTACACTTTTACATTTCTTAGAATTTTAAAGTTTGCAGTGGTAGCCT
TTGAGTTTTTTTACGACGAAAAAAAACACTTTTTTTCGTTTTTTTTACCGCCGTTTTATG
CGTGCCAATTCTATTCTATTTCTATTTTCTGTAGAATAGAATGCGTGCCAATTATTCATA
TAAGCATGAGCCTTTTTAAATTAATTTTTTTGTAAAGTGTACATCAGTCTTCTTACCTCT
CTGGTCATTGTTCTAGTGCCTGGTTATCATGTCTGAACGATTTGCAATTGCCCAACGAAT
GTAAATAAATTTGGTTTTAACTATT
| Gene3D |
6-blade_b-propeller_TolB-like (IPR011042) - T[24-303] 6.4E-91 - T[344-654] 8.0E-125 - T[655-949] 2.5E-90 - T[955-1295] 4.2E-81 |
| SMART |
LDLR_classB_rpt (IPR000033) - T[48-90] 5.4 - T[93-135] 2.5E-12 - T[136-179] 3.6E-15 - T[180-222] 5.1E-12 - T[235-282] 2.1 - T[377-419] 0.0014 - T[420-462] 3.1E-12 - T[463-506] 3.3E-15 - T[507-549] 1.6E-13 - T[550-590] 2.2E-4 - T[682-724] 8.4 - T[725-767] 1.0E-9 - T[768-811] 4.1E-10 - T[813-855] 1.8E-4 - T[856-897] 9.8 - T[994-1036] 0.24 - T[1037-1083] 7.3E-7 - T[1145-1187] 4.9E-7 - T[1188-1227] 3.8E-4 |
| ProSiteProfiles |
LDLR_classB_rpt (IPR000033) - T[68-112] 9.831 - T[113-155] 17.326 - T[156-199] 16.909 - T[200-221] 8.044 - T[260-302] 8.833 - T[397-439] 14.147 - T[440-482] 15.888 - T[483-526] 16.143 - T[527-569] 13.358 - T[570-610] 6.42 - T[702-744] 11.688 - T[745-787] 14.704 - T[788-832] 11.711 - T[833-875] 9.019 - T[876-916] 6.42 - T[1014-1060] 10.736 - T[1061-1091] 8.485 - T[1116-1164] 6.606 - T[1165-1207] 15.099 - T[1208-1230] 5.794 |
| Pfam |
LDLR_classB_rpt (IPR000033) - T[113-153] 1.5E-11 - T[156-197] 5.0E-15 - T[440-480] 7.7E-11 - T[484-524] 6.3E-10 - T[529-555] 1.2E-5 - T[745-785] 2.1E-5 - T[788-830] 7.1E-5 - T[1166-1204] 1.3E-5 |
| SMART |
EGF-like_dom (IPR000742) - T[310-349] 17.0 - T[617-654] 0.035 - T[923-962] 0.03 - T[1255-1292] 56.0 |
| SUPERFAMILY |
LDL_receptor-like_sf (IPR036055) - T[1295-1332] 8.25E-10 - T[1338-1376] 2.36E-6 |
| Pfam |
LDrepeatLR_classA_rpt (IPR002172) - T[1296-1332] 8.2E-12 - T[1338-1375] 5.3E-6 |
| ProSiteProfiles |
LDrepeatLR_classA_rpt (IPR002172) - T[1296-1333] 13.413 - T[1338-1376] 10.963 |
| SMART |
LDrepeatLR_classA_rpt (IPR002172) - T[1296-1334] 2.4E-14 - T[1338-1377] 2.2E-5 |
| CDD |
LDrepeatLR_classA_rpt (IPR002172) - T[1297-1332] 2.872E-11 - T[1339-1375] 6.15698E-5 |
| PRINTS |
LDrepeatLR_classA_rpt (IPR002172) - T[1308-1329] 1.0E-9 - T[1351-1372] 1.0E-9 |
| ProSitePatterns |
LDLR_class-A_CS (IPR023415) - T[1310-1332] . - T[1353-1375] . |
| Protein Name | Identity | Bit Score | e-value |
|---|---|---|---|
| LRP4_HUMAN | 35.782 % | 818 | 0 |
| LRP6_HUMAN | 43.82 % | 1339 | 0 |
| LRP5_HUMAN | 43.899 % | 1264 | 0 |