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- Transcript 'KH2012:KH.C7.481.v1....'
Transcript Model
Transcript Id
KH2012:KH.C7.481.v1.A.ND1-1
Possible name(s)
NOTCH1; NOTCH2; NOTCH3
Gene model
Location
KhC7 [3,039,857 / 3,061,504]
Amino acid sequence
Length: 1,398
>KH.C7.481.v1.A.ND1-1
QTLMTAIQGLASIVVMARIYFEITLARALLVFQGKNCSINIDDCAPSPCSYNSTCVDLIN
GYYCICPPGLNGTNCSINIDDCIGVFCGNGTCVDLINDYMCDCAIGFNGTNCTNNIDDCS
PGICNNGDCIDQVNNYTCSCFDGYTGDKCLIDIDECATDPCVNGTCVNLVNAYMCNCTAG
FDGTNCSNDINDCAPNPCVHGSCTDRVENYTCACDTGFTGRNCSIDINDCDPNPCDSCGN
CTDLLNDYNCTCPAGFSGKNCSIDINECTPGVCGNGTCVDMLQGYYCNCDIGFNGTNCTN
NIDDCAINHCANGGTCVDGVANYTCQCVPGYTGYNCSTDINDCDPNPCDSCGNCTDLLND
YNCTCPAGFSGKNCSIDINECTPGVCGNGTCVDKLNGYYCDCDLGFNGTNCLNNIDDCAI
NHCANGGTCVDGVANYTCQCAPGHTGYNCSIVADNVTNLFVYNVTSSALNVRWALSAYGH
NSTLVKIFPDSVPERTVTTNSTHFSNLLAGTNYTVSVQSQNAAGLSAPTTFSFQTAPGKP
ENVRITTAHTSLNISFDAMQGAVLYRVTISHNLAKNTTSTYVYFDGLNDGMQYTVSVVAF
SRNQLVLGVLSSLPSDPISISTYINACKPSPCVNGSCLINKNNYTCECEAGFTGMNCSID
IDDCKPNPCVNGSCTDQVNNYTCSCDPTFKGRNCSQDINSCTPNPCMNGKCSVDKNNYTC
ECEAGFTGRNCSIDIDDCSPNPCVNSMDCIDRVNDYQCDCTPGFVGKNCEKSYDDCHNVS
CNSFECVDGFLSYTCNCKNGYSGKNCEIAIAVKCLAQGHIRPGRRANQLCLGAGIIRSNI
NFCSKRQLAKAVTVFVESMELPPDELENEIILDTMSVKVRCSYVFILWKRPHDTVYKELT
EDKQNTCQMWRMYAKRLPSSLFASQKKRSAHQEVFDITSSPYIGFNRTHVSPTLSFPYTL
LRGLSRSTTFKMVLFKSTSLFPTKQKDVSKFSQVTQFVISGNNNSYGGKVQLINNDIKVT
PMQPVPSKPQRLYQLECAKYNQNTEDWDKKDCEFEPGVGTTPSRCQCDSKYNPYSEEIEE
QQQGSTFSCLVKEVYFPSAKVLSIVSKIGLWISLFGVFLTFVIYISIKQLRNRQPTIFIL
NICVCLFIVYITFLFGIQATETKTTCDASAMILHYALLAFWFWCGANTLNLYKLIVKVFG
SPDTLTPCVLYSTCYGLPLLIVGINAGATIFTTDLSLPEGEDSNYRHSAKCWLRHYSLYF
GFLLPMGLIILFNVVVFVLVISKLTCKRDKIRSSKSQKNSAKEGLSLAVTLCFMMGFAWI
FGYFLLIDGDLKLIEVMSWLFTLFNAGQGITIFYFNCLKQNQARRLWLDPLLAQCCNKKP
ITKVESVELSQTTNLSKL
Nucleotide sequence
Length: 4,772
>KH2012:KH.C7.481.v1.A.ND1-1
ACAGACACTGATGACTGCTATCCAAGGCCTTGCCAGCATTGTGGTAATGGCACGGATCTA
CTTCGAGATTACACTTGCGCGTGCCCTGTTGGTTTTCCAAGGGAAAAACTGCTCAATAAA
TATAGACGACTGTGCGCCTTCACCGTGTAGCTACAACTCTACGTGTGTGGATCTGATCAA
TGGATATTACTGCATTTGTCCGCCTGGATTAAACGGAACCAACTGTTCAATTAATATTGA
TGACTGTATTGGTGTCTTCTGTGGTAATGGGACTTGTGTGGATCTGATAAACGACTATAT
GTGTGATTGTGCCATTGGTTTTAATGGCACCAACTGTACAAACAACATAGATGACTGCTC
ACCTGGAATTTGTAATAATGGAGATTGTATTGACCAAGTAAATAACTACACTTGTTCTTG
CTTTGATGGATACACAGGAGATAAATGTCTAATAGATATAGATGAATGTGCTACAGACCC
ATGTGTAAATGGTACATGTGTAAATCTGGTGAATGCATATATGTGTAACTGCACTGCTGG
CTTTGATGGCACAAACTGCTCTAATGATATAAATGATTGCGCTCCAAATCCATGTGTGCA
TGGGAGTTGCACAGATAGGGTAGAAAACTATACATGTGCATGTGATACAGGATTTACTGG
CAGGAATTGCTCAATAGATATCAACGATTGTGACCCAAATCCATGCGATTCATGTGGAAA
TTGTACAGACTTGTTGAATGACTATAACTGTACATGCCCTGCTGGGTTTAGTGGAAAAAA
CTGCTCAATTGATATCAATGAATGTACACCTGGTGTATGCGGAAATGGAACTTGTGTTGA
TATGTTGCAGGGTTATTATTGTAACTGTGATATTGGTTTTAATGGAACAAACTGCACCAA
CAACATAGATGATTGTGCTATAAACCATTGTGCTAATGGCGGGACTTGTGTAGATGGAGT
GGCTAATTACACCTGTCAGTGCGTACCTGGCTATACGGGCTACAACTGCTCAACTGATAT
CAACGATTGTGACCCAAATCCATGCGATTCATGTGGAAATTGTACAGACTTGTTGAATGA
CTATAACTGTACATGCCCTGCTGGGTTTAGTGGAAAAAACTGCTCAATTGATATCAATGA
ATGTACACCTGGTGTATGTGGAAATGGAACTTGTGTTGATAAGTTAAATGGCTATTATTG
TGACTGTGATCTTGGTTTTAATGGAACAAACTGCCTTAACAACATAGATGATTGTGCTAT
AAACCATTGTGCTAATGGCGGGACTTGTGTAGATGGAGTGGCTAATTACACTTGTCAGTG
CGCACCTGGCCATACTGGCTACAACTGCTCAATTGTTGCGGACAATGTCACCAACTTATT
TGTCTACAATGTAACCTCATCTGCTCTAAATGTAAGATGGGCTCTATCAGCTTATGGCCA
CAACTCCACTCTTGTGAAGATTTTTCCAGACAGCGTACCAGAACGGACAGTAACAACTAA
CTCAACACATTTTTCAAACTTACTGGCCGGCACCAATTACACAGTTTCAGTTCAATCTCA
GAATGCAGCAGGGTTAAGTGCTCCAACAACTTTTAGTTTTCAAACAGCACCTGGCAAACC
TGAAAATGTAAGGATTACGACAGCACATACTTCACTGAATATATCATTTGATGCTATGCA
AGGAGCTGTTCTATACAGGGTGACAATTTCTCATAACCTAGCTAAAAATACAACCTCTAC
TTACGTGTATTTTGATGGCCTAAATGATGGAATGCAATACACTGTATCTGTGGTGGCATT
TTCACGAAATCAACTTGTGTTGGGAGTTCTTTCTAGTCTTCCATCTGATCCTATATCTAT
CTCAACATACATAAATGCATGCAAACCAAGTCCATGTGTAAATGGAAGTTGTTTAATTAA
TAAAAACAATTACACATGTGAGTGTGAAGCAGGATTCACCGGCATGAACTGTTCCATAGA
TATTGATGATTGCAAACCAAATCCATGTGTGAATGGCAGTTGTACTGACCAAGTCAACAA
CTATACTTGTTCCTGTGATCCCACTTTTAAAGGAAGAAATTGCTCTCAGGACATAAATTC
ATGCACACCAAATCCATGTATGAATGGAAAATGCTCAGTTGATAAAAACAATTACACTTG
TGAGTGTGAAGCAGGATTCACTGGCAGGAACTGTTCCATAGATATTGATGACTGCAGTCC
AAACCCATGTGTTAATTCTATGGATTGTATTGATAGAGTAAATGATTACCAATGCGATTG
TACACCAGGCTTTGTAGGCAAAAATTGTGAAAAAAGTTATGATGATTGCCACAATGTAAG
CTGCAACTCATTTGAATGCGTAGATGGTTTTCTCAGCTACACATGCAACTGTAAAAATGG
CTACAGCGGAAAAAATTGCGAAATTGCAATTGCCGTTAAATGTCTTGCCCAAGGACACAT
ACGCCCGGGCAGGCGTGCTAACCAACTGTGCTTAGGTGCTGGAATAATTAGATCAAACAT
TAACTTTTGCAGCAAACGACAGCTTGCCAAAGCTGTCACTGTCTTTGTGGAAAGCATGGA
ACTTCCACCAGATGAACTAGAAAACGAAATTATTCTGGATACAATGTCTGTGAAGGTAAG
ATGTAGTTATGTGTTCATTCTATGGAAAAGGCCCCATGACACGGTTTATAAAGAGCTAAC
AGAGGATAAACAGAATACATGCCAAATGTGGAGAATGTATGCAAAAAGGTTACCATCTTC
CTTATTTGCATCACAAAAAAAACGGAGTGCGCACCAAGAAGTATTTGATATTACATCTTC
TCCTTATATTGGGTTTAATAGAACACATGTATCACCAACCTTATCCTTTCCATATACTCT
TTTGAGAGGCTTGTCAAGATCTACTACTTTTAAAATGGTGTTATTTAAATCCACTTCACT
CTTTCCAACTAAACAAAAAGATGTGTCTAAGTTTAGCCAGGTCACACAATTCGTTATCAG
TGGAAATAATAACAGTTACGGTGGAAAAGTTCAATTGATTAATAATGACATAAAGGTAAC
ACCGATGCAACCTGTGCCGTCTAAGCCACAAAGACTTTATCAGTTGGAATGCGCAAAATA
TAACCAAAATACGGAGGACTGGGATAAAAAAGACTGCGAATTCGAACCTGGAGTAGGCAC
AACACCAAGCAGATGCCAATGCGATAGTAAATATAATCCGTATTCCGAAGAAATAGAGGA
ACAACAACAGGGATCTACATTCTCATGTTTAGTGAAAGAAGTTTATTTCCCATCTGCAAA
GGTTCTTAGTATTGTCAGTAAGATTGGTTTGTGGATTTCCCTATTTGGAGTTTTCCTAAC
ATTTGTCATCTACATTTCTATAAAGCAGTTAAGGAACAGGCAACCAACAATTTTTATTCT
GAACATCTGTGTCTGTCTTTTTATTGTTTACATCACCTTTCTCTTTGGAATTCAAGCAAC
TGAAACAAAGACTACATGCGATGCAAGTGCTATGATATTGCATTATGCCTTACTGGCTTT
CTGGTTTTGGTGTGGGGCAAACACACTCAATCTGTACAAGTTAATTGTGAAGGTCTTTGG
TTCTCCTGACACCCTTACACCATGTGTGCTGTACAGTACCTGTTATGGACTGCCTTTGTT
AATAGTTGGTATCAATGCAGGAGCTACTATTTTTACTACTGACTTATCGTTGCCCGAAGG
AGAAGATTCTAACTACAGACACAGCGCTAAATGTTGGTTGAGACATTACTCACTTTACTT
TGGCTTCTTGCTCCCAATGGGTCTTATAATTCTTTTCAATGTTGTGGTCTTTGTTCTTGT
AATCAGTAAACTGACTTGCAAGAGAGATAAGATTCGCTCATCAAAATCACAGAAGAACAG
TGCTAAGGAAGGGCTTTCACTTGCAGTAACGCTGTGTTTTATGATGGGATTTGCTTGGAT
TTTTGGCTACTTTCTGCTCATAGACGGCGATTTAAAATTAATAGAAGTAATGTCATGGCT
TTTTACTCTCTTTAATGCTGGCCAGGGAATAACAATCTTCTACTTTAACTGTTTAAAACA
AAACCAAGCACGAAGATTATGGTTGGACCCCTTGCTTGCTCAATGCTGTAACAAGAAACC
AATAACCAAAGTTGAAAGTGTGGAACTCAGTCAAACTACCAATCTATCCAAACTCTGACA
TTTGTTTTAAGAAAAGGAGTCCATGTCAATGGGTTGGCATATATACTGTACAATGAGTGA
AACGAGGCTGTTCTTTTTTGTATTTTTGACTTGGTCTGCATACACTGTATATTTTGTATT
GTGTTTAACTTGTCCGCACTTTGTTGTTGAAACATTTGGAACTTAGAGTATTTAAACAGT
GCCAGGCAGATAACAATATTATTCTATTTATGTTTTCATGTTACCATCATTACCATTTAG
ATGCGTTGAGGTTTTGTGTTGATTCAACGGTAAACAATGAATCATGGACATAAACAGTTG
CACAATGTCAAATATTTTTGTGGTATAACATGTTTTAGATATTAGTCAAATTTTCCGTTA
AAATCTATATTGGAAAATGTTTCGCTTCATAGAAAAATAAGGGTAAGGAAGTAGAAAAAG
GTGCAAAGTTAAAGTTCCATACTGATTGTTATATAACCAAGTGTATTGTGTTTGTGTATA
TTCTTTGGCAGATTACACCATGTGTTTTTATTGAATCGATTTTTCTTTTTTAAAGCACAT
TTTTGCATAATAAACTGCTTTAAATGGTTTTA
| SMART |
EGF-like_Ca-bd_dom (IPR001881) - T[40-76] 4.3E-8 - T[78-113] 3.7E-6 - T[115-150] 3.6E-6 - T[152-187] 1.2E-10 - T[189-224] 2.7E-8 - T[226-262] 2.6E-5 - T[264-299] 6.0E-7 - T[301-337] 3.2E-8 - T[339-375] 2.6E-5 - T[377-412] 2.0E-9 - T[414-450] 1.4E-7 - T[624-658] 0.023 - T[660-695] 5.0E-8 - T[697-732] 3.7E-4 - T[734-770] 4.7E-9 - T[772-807] 0.012 |
| ProSiteProfiles |
EGF-like_dom (IPR000742) - T[40-76] 20.49 - T[78-113] 14.55 - T[115-150] 15.6 - T[152-187] 18.533 - T[189-224] 17.808 - T[226-262] 16.921 - T[264-299] 16.223 - T[301-337] 23.452 - T[339-375] 16.921 - T[377-412] 16.467 - T[414-450] 22.372 - T[623-658] 13.926 - T[660-695] 16.897 - T[697-732] 17.519 - T[734-770] 21.062 - T[772-807] 10.984 |
| ProSitePatterns |
EGF_Ca-bd_CS (IPR018097) - T[40-64] . - T[226-250] . - T[339-363] . - T[414-438] . - T[734-758] . |
| SMART |
EGF-like_dom (IPR000742) - T[43-76] 3.1E-4 - T[81-113] 0.0071 - T[118-150] 2.2E-4 - T[155-187] 1.0E-5 - T[192-224] 7.6E-5 - T[229-262] 0.91 - T[267-299] 3.1E-4 - T[304-337] 5.0E-6 - T[342-375] 0.91 - T[380-412] 1.1E-4 - T[417-450] 2.9E-5 - T[626-658] 7.9E-5 - T[663-695] 0.002 - T[700-732] 9.0E-5 - T[737-770] 4.4E-5 - T[775-807] 0.0073 |
| Pfam |
EGF-like_dom (IPR000742) - T[44-72] 1.5E-5 - T[156-184] 1.3E-4 - T[193-222] 8.0E-5 - T[701-730] 4.7E-5 - T[738-768] 1.2E-4 |
| ProSitePatterns |
EGF-type_Asp/Asn_hydroxyl_site (IPR000152) - T[55-66] . - T[92-103] . - T[129-140] . - T[166-177] . - T[203-214] . - T[241-252] . - T[278-289] . - T[316-327] . - T[354-365] . - T[391-402] . - T[429-440] . - T[674-685] . - T[749-760] . - T[786-797] . |
| ProSitePatterns |
EGF-like_CS (IPR013032) - T[64-75] . - T[101-112] . - T[101-112] . - T[138-149] . - T[138-149] . - T[175-186] . - T[175-186] . - T[212-223] . - T[212-223] . - T[250-261] . - T[250-261] . - T[287-298] . - T[287-298] . - T[325-336] . - T[325-336] . - T[363-374] . - T[363-374] . - T[400-411] . - T[400-411] . - T[438-449] . - T[646-657] . - T[646-657] . - T[683-694] . - T[720-731] . - T[720-731] . - T[758-769] . - T[758-769] . - T[795-806] . - T[795-806] . |
| SUPERFAMILY |
Growth_fac_rcpt_cys_sf (IPR009030) - T[65-193] 5.96E-13 - T[177-305] 6.75E-11 - T[289-418] 5.96E-12 - T[623-738] 4.39E-9 |
| Pfam |
EGF-like_CS (IPR013032) - T[87-107] 1.2E-4 - T[310-331] 2.3E-6 - T[386-406] 0.011 - T[423-443] 1.2E-5 - T[669-687] 0.0064 |
| SMART |
FN3_dom (IPR003961) - T[453-526] 6.6E-6 - T[537-608] 4.3E-4 |
| CDD |
FN3_dom (IPR003961) - T[454-535] 1.36478E-8 - T[537-622] 2.08009E-5 |
| ProSiteProfiles |
FN3_dom (IPR003961) - T[455-539] 10.691 |
| SUPERFAMILY |
FN3_sf (IPR036116) - T[456-604] 2.51E-13 |
| Gene3D |
Ig-like_fold (IPR013783) - T[457-538] 8.5E-9 - T[539-622] 1.3E-5 |
| Pfam |
GPCR_2_secretin-like (IPR000832) - T[1100-1352] 1.2E-27 |
| ProSiteProfiles |
GPCR_2-like (IPR017981) - T[1102-1360] 24.003 |
| Protein Name | Identity | Bit Score | e-value |
|---|---|---|---|
| NOTC3_HUMAN | 32.847 % | 389 | 2.64E-111 |
| NOTC2_HUMAN | 44.469 % | 372 | 7.9E-106 |
| NOTC1_HUMAN | 44.444 % | 354 | 4.62E-100 |