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Gene Card
Best human hits
ACLY; SUCLG1
Species
Unique Gene ID
Phmamm.g00002716
Gene Model ID
Phmamm.CG.MTP2014.S80.g02716
Location
S80:207457..208453
Transcript Models and Sequences
AHC0AAA107YA23
Plate: Plate_107_A23
AHC0AAA183YO01
Plate: Plate_183_O01
AHC0AAA189YA07
Plate: Plate_189_A07
AHC0AAA194YE13
Plate: Plate_194_E13
AHC0AAA221YB05
Plate: Plate_221_B05
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
CoA_lig_alpha | TIGRFAM | Succinyl-CoA ligase, alpha subunit |
CoA_lig_alpha | Hamap | Succinyl-CoA ligase, alpha subunit |
CoA-bd | SMART | CoA-binding |
CoA_ligase | Pfam | ATP-citrate lyase/succinyl-CoA ligase |
Succinyl-CoA_synth-like | Gene3D | Succinyl-CoA synthetase-like |
Cit_synth/succinyl-CoA_lig_AS | ProSitePatterns | ATP-citrate lyase/succinyl-CoA ligase, active site |
Succinyl-CoA_synth-like | SUPERFAMILY | Succinyl-CoA synthetase-like |
CoA-bd | Pfam | CoA-binding |
CoA_lig_alpha | PIRSF | Succinyl-CoA ligase, alpha subunit |
Citrt_syn/SCS-alpha_CS | ProSitePatterns | ATP-citrate lyase/succinyl-CoA ligase, conserved site |
NAD(P)-bd_dom_sf | SUPERFAMILY | NAD(P)-binding domain superfamily |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
RNA binding | Orthology | molecular function |
catalytic activity | Orthology | molecular function |
protein binding | Blast | molecular function |
ATP binding | Blast | molecular function |
extracellular region | Blast | cellular component |
nucleoplasm | Blast | cellular component |
cytoplasm | Blast | cellular component |
mitochondrion | Orthology | cellular component |
mitochondrial inner membrane | Orthology | cellular component |
mitochondrial matrix | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
metabolic process | Orthology | biological process |
membrane | Blast | cellular component |
transferase activity | Blast | molecular function |
ligase activity | Orthology | molecular function |
metal ion binding | Blast | molecular function |
cofactor binding | Orthology | molecular function |
extracellular exosome | Orthology | cellular component |
oxidation-reduction process | Orthology | biological process |
cellular metabolic process | Orthology | biological process |
cytoplasmic part | Blast | cellular component |
macromolecular complex | Blast | cellular component |
cytoplasmic vesicle | Blast | cellular component |
lysosome | Blast | cellular component |
vacuolar part | Blast | cellular component |
endomembrane system | Blast | cellular component |
intracellular organelle lumen | Blast | cellular component |
intracellular organelle part | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nucleotide binding | Hs | molecular function |
RNA binding | Hs | molecular function |
catalytic activity | Hs | molecular function |
succinate-CoA ligase (ADP-forming) activity | Hs | molecular function |
succinate-CoA ligase (GDP-forming) activity | Hs | molecular function |
mitochondrion | Hs | cellular component |
mitochondrial inner membrane | Hs | cellular component |
mitochondrial matrix | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
tricarboxylic acid cycle | Hs | biological process |
metabolic process | Hs | biological process |
ligase activity | Hs | molecular function |
cofactor binding | Hs | molecular function |
extracellular exosome | Hs | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 413 | 2.85e-145 |
RNA binding | Hs | molecular function | 413 | 2.85e-145 |
catalytic activity | Hs | molecular function | 413 | 2.85e-145 |
ATP citrate synthase activity | Hs | molecular function | 89.7 | 1.33e-19 |
succinate-CoA ligase (ADP-forming) activity | Hs | molecular function | 413 | 2.85e-145 |
succinate-CoA ligase (GDP-forming) activity | Hs | molecular function | 413 | 2.85e-145 |
protein binding | Hs | molecular function | 89.7 | 1.33e-19 |
ATP binding | Hs | molecular function | 89.7 | 1.33e-19 |
extracellular region | Hs | cellular component | 89.7 | 1.33e-19 |
nucleoplasm | Hs | cellular component | 89.7 | 1.33e-19 |
cytoplasm | Hs | cellular component | 89.7 | 1.33e-19 |
mitochondrion | Hs | cellular component | 413 | 2.85e-145 |
mitochondrial inner membrane | Hs | cellular component | 413 | 2.85e-145 |
mitochondrial matrix | Hs | cellular component | 413 | 2.85e-145 |
cytosol | Hs | cellular component | 413 | 2.85e-145 |
plasma membrane | Hs | cellular component | 413 | 2.85e-145 |
citrate lyase complex | Hs | cellular component | 89.7 | 1.33e-19 |
membrane | Hs | cellular component | 89.7 | 1.33e-19 |
transferase activity | Hs | molecular function | 89.7 | 1.33e-19 |
lyase activity | Hs | molecular function | 89.7 | 1.33e-19 |
ligase activity | Hs | molecular function | 413 | 2.85e-145 |
azurophil granule lumen | Hs | cellular component | 89.7 | 1.33e-19 |
metal ion binding | Hs | molecular function | 89.7 | 1.33e-19 |
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer | Hs | molecular function | 89.7 | 1.33e-19 |
cofactor binding | Hs | molecular function | 413 | 2.85e-145 |
extracellular exosome | Hs | cellular component | 413 | 2.85e-145 |
ficolin-1-rich granule lumen | Hs | cellular component | 89.7 | 1.33e-19 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
catalytic activity | TIGRFAM | molecular function | 1.1E-132 |
metabolic process | TIGRFAM | biological process | 1.1E-132 |
cofactor binding | SMART | molecular function | 7.8E-32 |