IPR Term	Analysis	Definition
Na/K_ATPase_sub_beta	TIGRFAM	Sodium/potassium-transporting ATPase subunit beta
Na/K_ATPase_sub_beta	PANTHER	Sodium/potassium-transporting ATPase subunit beta
Na/K_ATPase_sub_beta	Pfam	Sodium/potassium-transporting ATPase subunit beta
Na/K_ATPase_sub_beta_sf	Gene3D	Sodium/potassium-transporting ATPase subunit beta superfamily

GO Term	Annotation Origin	Type
response to hypoxia	Orthology	biological process
protein binding	Orthology	molecular function
ATP binding	Orthology	molecular function
intracellular	Orthology	cellular component
cytoplasm	Orthology	cellular component
plasma membrane	Orthology	cellular component
ion transport	Orthology	biological process
sodium ion transport	Orthology	biological process
cell adhesion	Orthology	biological process
protein C-terminus binding	Orthology	molecular function
regulation of gene expression	Orthology	biological process
membrane	Orthology	cellular component
integral component of membrane	Orthology	cellular component
basolateral plasma membrane	Orthology	cellular component
apical plasma membrane	Orthology	cellular component
protein kinase binding	Orthology	molecular function
metal ion transport	Orthology	biological process
melanosome	Orthology	cellular component
myelin sheath	Orthology	cellular component
extracellular exosome	Orthology	cellular component
extracellular vesicle	Orthology	cellular component
nucleus	Orthology	cellular component
nuclear envelope	Orthology	cellular component
integral component of plasma membrane	Orthology	cellular component
transcription, DNA-templated	Orthology	biological process
regulation of transcription, DNA-templated	Orthology	biological process
monovalent inorganic cation transport	Orthology	biological process
response to lipopolysaccharide	Orthology	biological process
positive regulation of transcription from RNA polymerase II promoter	Orthology	biological process
nucleoside-triphosphatase regulator activity	Orthology	molecular function
positive regulation of hydrolase activity	Orthology	biological process
enzyme activator activity	Orthology	molecular function
transmembrane transport	Orthology	biological process
nucleoside-triphosphatase activity	Orthology	molecular function
macromolecular complex	Orthology	cellular component
membrane raft	Orthology	cellular component
plasma membrane region	Orthology	cellular component
cellular process	Orthology	biological process
cell	Orthology	cellular component
binding	Orthology	molecular function
intracellular signal transduction	Orthology	biological process
cell junction	Orthology	cellular component
macromolecular complex binding	Orthology	molecular function
metal ion binding	Orthology	molecular function
metabolic process	Orthology	biological process
cell migration	Orthology	biological process
immune system process	Orthology	biological process
enzyme binding	Orthology	molecular function
protein localization to membrane	Orthology	biological process
regulation of signaling	Orthology	biological process
organelle inner membrane	Orthology	cellular component
nuclear membrane	Orthology	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
response to hypoxia	Hs	biological process
ATPase activator activity	Hs	molecular function
sodium:potassium-exchanging ATPase activity	Hs	molecular function
protein binding	Hs	molecular function
ATP binding	Hs	molecular function
intracellular	Hs	cellular component
cytoplasm	Hs	cellular component
plasma membrane	Hs	cellular component
sodium:potassium-exchanging ATPase complex	Hs	cellular component
caveola	Hs	cellular component
ion transport	Hs	biological process
potassium ion transport	Hs	biological process
sodium ion transport	Hs	biological process
cellular calcium ion homeostasis	Hs	biological process
cellular sodium ion homeostasis	Hs	biological process
cell adhesion	Hs	biological process
protein C-terminus binding	Hs	molecular function
drug binding	Hs	molecular function
potassium ion import	Hs	biological process
establishment or maintenance of transmembrane electrochemical gradient	Hs	biological process
regulation of gene expression	Hs	biological process
regulation of cardiac muscle contraction by calcium ion signaling	Hs	biological process
intercalated disc	Hs	cellular component
membrane	Hs	cellular component
integral component of membrane	Hs	cellular component
basolateral plasma membrane	Hs	cellular component
apical plasma membrane	Hs	cellular component
ATPase activity	Hs	molecular function
protein kinase binding	Hs	molecular function
MHC class II protein complex binding	Hs	molecular function
metal ion transport	Hs	biological process
potassium ion binding	Hs	molecular function
sodium ion binding	Hs	molecular function
positive regulation of ATPase activity	Hs	biological process
ion transmembrane transport	Hs	biological process
sarcolemma	Hs	cellular component
melanosome	Hs	cellular component
myelin sheath	Hs	cellular component
ATP metabolic process	Hs	biological process
protein stabilization	Hs	biological process
leukocyte migration	Hs	biological process
ATPase binding	Hs	molecular function
cardiac muscle contraction	Hs	biological process
extracellular exosome	Hs	cellular component
protein localization to plasma membrane	Hs	biological process
membrane repolarization	Hs	biological process
membrane repolarization during cardiac muscle cell action potential	Hs	biological process
regulation of calcium ion transmembrane transport	Hs	biological process
positive regulation of potassium ion import	Hs	biological process
extracellular vesicle	Hs	cellular component
regulation of cardiac conduction	Hs	biological process
nucleus	Hs	cellular component
nuclear envelope	Hs	cellular component
nuclear inner membrane	Hs	cellular component
integral component of plasma membrane	Hs	cellular component
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
hydrogen:potassium-exchanging ATPase activity	Hs	molecular function
monovalent inorganic cation transmembrane transporter activity	Hs	molecular function
monovalent inorganic cation transport	Hs	biological process
response to lipopolysaccharide	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
hydrogen ion transmembrane transport	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
ATPase activator activity	Hs	molecular function	162	5.59e-48
sodium:potassium-exchanging ATPase activity	Hs	molecular function	162	5.59e-48
protein binding	Hs	molecular function	162	5.59e-48
ATP binding	Hs	molecular function	140	3.98e-39
intracellular	Hs	cellular component	140	3.98e-39
cytoplasm	Hs	cellular component	162	5.59e-48
plasma membrane	Hs	cellular component	162	5.59e-48
sodium:potassium-exchanging ATPase complex	Hs	cellular component	162	5.59e-48
caveola	Hs	cellular component	140	3.98e-39
protein C-terminus binding	Hs	molecular function	140	3.98e-39
drug binding	Hs	molecular function	140	3.98e-39
intercalated disc	Hs	cellular component	140	3.98e-39
membrane	Hs	cellular component	162	5.59e-48
integral component of membrane	Hs	cellular component	162	5.59e-48
basolateral plasma membrane	Hs	cellular component	140	3.98e-39
apical plasma membrane	Hs	cellular component	162	5.59e-48
ATPase activity	Hs	molecular function	140	3.98e-39
protein kinase binding	Hs	molecular function	140	3.98e-39
MHC class II protein complex binding	Hs	molecular function	140	3.98e-39
potassium ion binding	Hs	molecular function	140	3.98e-39
sodium ion binding	Hs	molecular function	140	3.98e-39
sarcolemma	Hs	cellular component	140	3.98e-39
melanosome	Hs	cellular component	127	1.53e-34
myelin sheath	Hs	cellular component	140	3.98e-39
ATPase binding	Hs	molecular function	162	5.59e-48
extracellular exosome	Hs	cellular component	140	3.98e-39
extracellular vesicle	Hs	cellular component	140	3.98e-39

GO Term	Analysis	Type	e-value
sodium:potassium-exchanging ATPase complex	Pfam	cellular component	1.3E-78
potassium ion transport	Pfam	biological process	1.3E-78
sodium ion transport	Pfam	biological process	1.3E-78