Gene Card
Best human hits
EIF2S2; EIF4G1; EIF5
Species
Unique Gene ID
Phmamm.g00010844
Gene Model ID
Phmamm.CG.MTP2014.S641.g10844
Location
S641:71462..76063
Transcript Models and Sequences
Phmamm.CG.MTP2014.S641.g10844.01.t
Phmamm.CG.MTP2014.S641.g10844.02.t
AHC0AAA28YA18
Plate: Plate_28_A18
AHC0AAA32YK01
Plate: Plate_32_K01
AHC0AAA35YE18
Plate: Plate_35_E18
AHC0AAA57YF14
Plate: Plate_57_F14
AHC0AAA69YM15
Plate: Plate_69_M15
AHC0AAA71YK23
Plate: Plate_71_K23
AHC0AAA72YA24
Plate: Plate_72_A24
AHC0AAA126YB14
Plate: Plate_126_B14
AHC0AAA137YC13
Plate: Plate_137_C13
AHC0AAA145YG09
Plate: Plate_145_G09
AHC0AAA146YE08
Plate: Plate_146_E08
AHC0AAA154YE24
Plate: Plate_154_E24
AHC0AAA87YA13
Plate: Plate_87_A13
AHC0AAA88YF22
Plate: Plate_88_F22
AHC0AAA90YM21
Plate: Plate_90_M21
AHC0AAA93YI03
Plate: Plate_93_I03
AHC0AAA183YB13
Plate: Plate_183_B13
AHC0AAA189YI21
Plate: Plate_189_I21
AHC0AAA229YP12
Plate: Plate_229_P12
AHC0AAA265YG07
Plate: Plate_265_G07
AHC0AAA269YC16
Plate: Plate_269_C16
n/a
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IPR Term | Analysis | Definition |
---|---|---|
MIF4-like_sf | Gene3D | MIF4G-like domain superfamily |
Transl_init_fac_IF2/IF5 | Pfam | Translation initiation factor IF2/IF5 |
W2_domain | ProSiteProfiles | W2 domain |
W2_domain | Pfam | W2 domain |
W2_domain | SMART | W2 domain |
Transl_init_fac_IF2/IF5_N | SUPERFAMILY | Translation initiation factor IF2/IF5, N-terminal |
ARM-type_fold | SUPERFAMILY | Armadillo-type fold |
Transl_init_fac_IF2/IF5 | SMART | Translation initiation factor IF2/IF5 |
Transl_init_fac_IF2/IF5_Zn-bd | SUPERFAMILY | Translation initiation factor IF2/IF5, zinc-binding |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
RNA binding | Orthology | molecular function |
GTPase activity | Orthology | molecular function |
binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Blast | molecular function |
GTP binding | Orthology | molecular function |
nucleus | Blast | cellular component |
cytoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
translational initiation | Orthology | biological process |
membrane | Blast | cellular component |
identical protein binding | Blast | molecular function |
metal ion binding | Blast | molecular function |
regulation of gene expression | Orthology | biological process |
cell adhesion molecule binding | Orthology | molecular function |
positive regulation of GTPase activity | Orthology | biological process |
macromolecular complex | Blast | cellular component |
cytoplasmic part | Blast | cellular component |
intracellular organelle part | Blast | cellular component |
ribosome | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nucleotide binding | Hs | molecular function |
formation of translation preinitiation complex | Hs | biological process |
RNA binding | Hs | molecular function |
translation initiation factor activity | Hs | molecular function |
GTPase activity | Hs | molecular function |
binding | Hs | molecular function |
protein binding | Hs | molecular function |
GTP binding | Hs | molecular function |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
translation | Hs | biological process |
translational initiation | Hs | biological process |
regulation of translational initiation | Hs | biological process |
translation factor activity, RNA binding | Hs | molecular function |
cadherin binding | Hs | molecular function |
eukaryotic initiation factor eIF2 binding | Hs | molecular function |
activation of GTPase activity | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 403 | 2.83e-138 |
RNA binding | Hs | molecular function | 403 | 2.83e-138 |
mRNA binding | Hs | molecular function | 40.0 | 0.003 |
translation initiation factor activity | Hs | molecular function | 403 | 2.83e-138 |
GTPase activity | Hs | molecular function | 403 | 2.83e-138 |
binding | Hs | molecular function | 403 | 2.83e-138 |
protein binding | Hs | molecular function | 403 | 2.83e-138 |
ATP binding | Hs | molecular function | 40.0 | 0.003 |
GTP binding | Hs | molecular function | 403 | 2.83e-138 |
nucleus | Hs | cellular component | 40.0 | 0.003 |
cytoplasm | Hs | cellular component | 403 | 2.83e-138 |
cytosol | Hs | cellular component | 403 | 2.83e-138 |
polysome | Hs | cellular component | 40.0 | 0.003 |
eukaryotic translation initiation factor 2 complex | Hs | cellular component | 51.2 | 5.76e-07 |
plasma membrane | Hs | cellular component | 403 | 2.83e-138 |
translation factor activity, RNA binding | Hs | molecular function | 403 | 2.83e-138 |
eukaryotic initiation factor 4E binding | Hs | molecular function | 40.0 | 0.003 |
membrane | Hs | cellular component | 40.0 | 0.003 |
eukaryotic translation initiation factor 4F complex | Hs | cellular component | 40.0 | 0.003 |
cytosolic small ribosomal subunit | Hs | cellular component | 40.0 | 0.003 |
translation initiation factor binding | Hs | molecular function | 40.0 | 0.003 |
protein complex scaffold activity | Hs | molecular function | 40.0 | 0.003 |
identical protein binding | Hs | molecular function | 40.0 | 0.003 |
cadherin binding | Hs | molecular function | 403 | 2.83e-138 |
metal ion binding | Hs | molecular function | 51.2 | 5.76e-07 |
eukaryotic initiation factor eIF2 binding | Hs | molecular function | 403 | 2.83e-138 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
translation initiation factor activity | SMART | molecular function | 5.6E-54 |
binding | SUPERFAMILY | molecular function | 3.17E-24 |
protein binding | SMART | molecular function | 6.2E-26 |
translational initiation | SMART | biological process | 5.6E-54 |