IPR Term	Analysis	Definition
SQSTM_UBA	Pfam	Sequestosome-1, UBA domain
PB1_dom	ProSiteProfiles	PB1 domain
UBA-like_sf	SUPERFAMILY	UBA-like superfamily
PB1_dom	Pfam	PB1 domain
PB1_dom	SMART	PB1 domain

GO Term	Annotation Origin	Type
negative regulation of transcription from RNA polymerase II promoter	Orthology	biological process
immune system process	Orthology	biological process
protein serine/threonine kinase activity	Orthology	molecular function
protein binding	Orthology	molecular function
nucleus	Orthology	cellular component
nucleoplasm	Orthology	cellular component
cytoplasm	Orthology	cellular component
lysosome	Orthology	cellular component
endosome	Orthology	cellular component
endoplasmic reticulum	Orthology	cellular component
cytosol	Orthology	cellular component
plasma membrane	Blast	cellular component
protein phosphorylation	Orthology	biological process
apoptotic process	Orthology	biological process
protein localization	Orthology	biological process
zinc ion binding	Orthology	molecular function
membrane	Blast	cellular component
enzyme binding	Orthology	molecular function
protein kinase binding	Orthology	molecular function
cell junction	Blast	cellular component
cell differentiation	Orthology	biological process
cytoplasmic vesicle	Orthology	cellular component
ubiquitin protein ligase binding	Orthology	molecular function
intracellular signal transduction	Orthology	biological process
identical protein binding	Orthology	molecular function
protein homodimerization activity	Orthology	molecular function
positive regulation of apoptotic process	Orthology	biological process
negative regulation of apoptotic process	Orthology	biological process
intracellular membrane-bounded organelle	Orthology	cellular component
positive regulation of transcription from RNA polymerase II promoter	Orthology	biological process
metal ion binding	Orthology	molecular function
extracellular exosome	Orthology	cellular component
cytoplasmic part	Orthology	cellular component
organelle organization	Orthology	biological process
intracellular non-membrane-bounded organelle	Orthology	cellular component
macromolecular complex	Orthology	cellular component
response to stress	Orthology	biological process
vacuole	Orthology	cellular component
proteolysis	Orthology	biological process
intracellular transport	Orthology	biological process
intracellular part	Orthology	cellular component
nuclear body	Orthology	cellular component
organelle part	Orthology	cellular component
receptor binding	Orthology	molecular function
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
regulation of signal transduction	Orthology	biological process
small GTPase mediated signal transduction	Orthology	biological process
protein oligomerization	Orthology	biological process
cytokine-mediated signaling pathway	Orthology	biological process
cell projection part	Orthology	cellular component
microtubule	Orthology	cellular component
plasma membrane region	Orthology	cellular component
neuron part	Orthology	cellular component
cellular response to stress	Orthology	biological process
protein localization to membrane	Orthology	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
pre-autophagosomal structure	Hs	cellular component
autophagy of mitochondrion	Hs	biological process
mitophagy	Hs	biological process
P-body	Hs	cellular component
positive regulation of protein phosphorylation	Hs	biological process
immune system process	Hs	biological process
response to ischemia	Hs	biological process
protein serine/threonine kinase activity	Hs	molecular function
protein kinase C binding	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
cytoplasm	Hs	cellular component
lysosome	Hs	cellular component
endosome	Hs	cellular component
late endosome	Hs	cellular component
autophagosome	Hs	cellular component
endoplasmic reticulum	Hs	cellular component
cytosol	Hs	cellular component
protein phosphorylation	Hs	biological process
ubiquitin-dependent protein catabolic process	Hs	biological process
autophagy	Hs	biological process
apoptotic process	Hs	biological process
endosome organization	Hs	biological process
protein localization	Hs	biological process
zinc ion binding	Hs	molecular function
regulation of mitochondrion organization	Hs	biological process
endosomal transport	Hs	biological process
inclusion body	Hs	cellular component
aggresome	Hs	cellular component
macroautophagy	Hs	biological process
PML body	Hs	cellular component
enzyme binding	Hs	molecular function
protein kinase binding	Hs	molecular function
sarcomere	Hs	cellular component
cell differentiation	Hs	biological process
receptor tyrosine kinase binding	Hs	molecular function
cytoplasmic vesicle	Hs	cellular component
ubiquitin protein ligase binding	Hs	molecular function
ionotropic glutamate receptor binding	Hs	molecular function
intracellular signal transduction	Hs	biological process
aggrephagy	Hs	biological process
SH2 domain binding	Hs	molecular function
identical protein binding	Hs	molecular function
protein homodimerization activity	Hs	molecular function
positive regulation of apoptotic process	Hs	biological process
negative regulation of apoptotic process	Hs	biological process
regulation of I-kappaB kinase/NF-kappaB signaling	Hs	biological process
ubiquitin binding	Hs	molecular function
intracellular membrane-bounded organelle	Hs	cellular component
negative regulation of growth of symbiont in host	Hs	biological process
amphisome	Hs	cellular component
autolysosome	Hs	cellular component
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
regulation of Ras protein signal transduction	Hs	biological process
metal ion binding	Hs	molecular function
protein heterooligomerization	Hs	biological process
regulation of protein complex stability	Hs	biological process
extracellular exosome	Hs	cellular component
interleukin-1-mediated signaling pathway	Hs	biological process
K63-linked polyubiquitin modification-dependent protein binding	Hs	molecular function
sperm midpiece	Hs	cellular component
Lewy body	Hs	cellular component
response to mitochondrial depolarisation	Hs	biological process
positive regulation of protein localization to plasma membrane	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
pre-autophagosomal structure	Hs	cellular component	68.6	3.28e-13
P-body	Hs	cellular component	68.6	3.28e-13
protein serine/threonine kinase activity	Hs	molecular function	68.6	3.28e-13
protein kinase C binding	Hs	molecular function	68.6	3.28e-13
protein binding	Hs	molecular function	68.6	3.28e-13
nucleus	Hs	cellular component	68.6	3.28e-13
nucleoplasm	Hs	cellular component	68.6	3.28e-13
cytoplasm	Hs	cellular component	68.6	3.28e-13
lysosome	Hs	cellular component	68.6	3.28e-13
endosome	Hs	cellular component	68.6	3.28e-13
late endosome	Hs	cellular component	68.6	3.28e-13
autophagosome	Hs	cellular component	68.6	3.28e-13
endoplasmic reticulum	Hs	cellular component	68.6	3.28e-13
cytosol	Hs	cellular component	68.6	3.28e-13
plasma membrane	Hs	cellular component	38.5	0.003
bicellular tight junction	Hs	cellular component	38.5	0.003
zinc ion binding	Hs	molecular function	68.6	3.28e-13
membrane	Hs	cellular component	38.5	0.003
inclusion body	Hs	cellular component	68.6	3.28e-13
aggresome	Hs	cellular component	68.6	3.28e-13
PML body	Hs	cellular component	68.6	3.28e-13
enzyme binding	Hs	molecular function	68.6	3.28e-13
protein kinase binding	Hs	molecular function	68.6	3.28e-13
sarcomere	Hs	cellular component	68.6	3.28e-13
cell junction	Hs	cellular component	38.5	0.003
receptor tyrosine kinase binding	Hs	molecular function	68.6	3.28e-13
cytoplasmic vesicle	Hs	cellular component	68.6	3.28e-13
ubiquitin protein ligase binding	Hs	molecular function	68.6	3.28e-13
ionotropic glutamate receptor binding	Hs	molecular function	68.6	3.28e-13
SH2 domain binding	Hs	molecular function	68.6	3.28e-13
identical protein binding	Hs	molecular function	68.6	3.28e-13
protein homodimerization activity	Hs	molecular function	68.6	3.28e-13
ubiquitin binding	Hs	molecular function	68.6	3.28e-13
intracellular membrane-bounded organelle	Hs	cellular component	68.6	3.28e-13
amphisome	Hs	cellular component	68.6	3.28e-13
autolysosome	Hs	cellular component	68.6	3.28e-13
metal ion binding	Hs	molecular function	68.6	3.28e-13
extracellular exosome	Hs	cellular component	68.6	3.28e-13
K63-linked polyubiquitin modification-dependent protein binding	Hs	molecular function	68.6	3.28e-13
sperm midpiece	Hs	cellular component	68.6	3.28e-13
Lewy body	Hs	cellular component	68.6	3.28e-13

GO Term	Analysis	Type	e-value
protein binding	SUPERFAMILY	molecular function	6.8E-14