Gene Card
Best human hits
VAV1; VAV2; VAV3
Species
Unique Gene ID
Phmamm.g00009452
Gene Model ID
Phmamm.CG.MTP2014.S497.g09452
Location
S497:90937..109804
Transcript Models and Sequences
AHC0AAA1YC24
Plate: Plate_1_C24
AHC0AAA41YI21
Plate: Plate_41_I21
AHC0AAA41YM04
Plate: Plate_41_M04
AHC0AAA54YI10
Plate: Plate_54_I10
AHC0AAA94YJ23
Plate: Plate_94_J23
AHC0AAA54YK12
Plate: Plate_54_K12
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
CH-domain | Pfam | Calponin homology domain |
SH3_domain | ProSiteProfiles | SH3 domain |
SH2_dom_sf | SUPERFAMILY | SH2 domain superfamily |
PE/DAG-bd | ProSiteProfiles | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
CH-domain | ProSiteProfiles | Calponin homology domain |
PH_domain | SMART | Pleckstrin homology domain |
CH-domain | SMART | Calponin homology domain |
CH-domain | CDD | Calponin homology domain |
PH_domain | ProSiteProfiles | Pleckstrin homology domain |
SH3_domain | Pfam | SH3 domain |
PH_domain | Pfam | Pleckstrin homology domain |
SH2 | ProSiteProfiles | SH2 domain |
SH2_dom_sf | Gene3D | SH2 domain superfamily |
DBL_dom_sf | SUPERFAMILY | Dbl homology (DH) domain superfamily |
DH-domain | Pfam | Dbl homology (DH) domain |
PH-like_dom_sf | Gene3D | PH-like domain superfamily |
SH3-like_dom_sf | SUPERFAMILY | SH3-like domain superfamily |
SH3_domain | PRINTS | SH3 domain |
CH_dom_sf | Gene3D | CH domain superfamily |
SH2 | Pfam | SH2 domain |
DH-domain | CDD | Dbl homology (DH) domain |
DBL_dom_sf | Gene3D | Dbl homology (DH) domain superfamily |
Vav1 | PANTHER | Protein vav1 |
SH2 | SMART | SH2 domain |
DH-domain | ProSiteProfiles | Dbl homology (DH) domain |
SH3_domain | SMART | SH3 domain |
PE/DAG-bd | CDD | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
DH-domain | SMART | Dbl homology (DH) domain |
CH_dom_sf | SUPERFAMILY | CH domain superfamily |
GO Term | Annotation Origin | Type |
---|---|---|
angiogenesis | Orthology | biological process |
transcription factor activity, sequence-specific DNA binding | Orthology | molecular function |
GTPase activator activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
intracellular | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
regulation of transcription, DNA-templated | Orthology | biological process |
immune response | Orthology | biological process |
cellular response to DNA damage stimulus | Orthology | biological process |
signal transduction | Orthology | biological process |
G-protein coupled receptor signaling pathway | Orthology | biological process |
small GTPase mediated signal transduction | Orthology | biological process |
positive regulation of signal transduction | Orthology | biological process |
cell migration | Orthology | biological process |
cytokine-mediated signaling pathway | Orthology | biological process |
cell projection assembly | Orthology | biological process |
intracellular signal transduction | Orthology | biological process |
positive regulation of apoptotic process | Orthology | biological process |
regulation of GTPase activity | Orthology | biological process |
positive regulation of GTPase activity | Orthology | biological process |
metal ion binding | Orthology | molecular function |
regulation of molecular function | Orthology | biological process |
extracellular exosome | Orthology | cellular component |
enzyme binding | Orthology | molecular function |
molecular function regulator | Orthology | molecular function |
receptor binding | Orthology | molecular function |
cell junction | Orthology | cellular component |
membrane organization | Orthology | biological process |
organelle organization | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
cellular component organization | Orthology | biological process |
blood coagulation | Orthology | biological process |
cellular process | Orthology | biological process |
immune system process | Orthology | biological process |
animal organ development | Orthology | biological process |
cell differentiation | Orthology | biological process |
chemotaxis | Orthology | biological process |
regulation of signal transduction | Orthology | biological process |
cell adhesion | Orthology | biological process |
innate immune response | Orthology | biological process |
phosphorylation | Orthology | biological process |
organic substance metabolic process | Orthology | biological process |
phosphotransferase activity, alcohol group as acceptor | Orthology | molecular function |
kinase activity | Orthology | molecular function |
cellular metabolic process | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
phosphotyrosine residue binding | Hs | molecular function | 524 | 7.93e-173 |
transcription factor activity, sequence-specific DNA binding | Hs | molecular function | 502 | 8.96e-165 |
SH3/SH2 adaptor activity | Hs | molecular function | 520 | 2.61e-171 |
guanyl-nucleotide exchange factor activity | Hs | molecular function | 524 | 7.93e-173 |
Rho guanyl-nucleotide exchange factor activity | Hs | molecular function | 524 | 7.93e-173 |
GTPase activator activity | Hs | molecular function | 520 | 2.61e-171 |
epidermal growth factor receptor binding | Hs | molecular function | 524 | 7.93e-173 |
protein binding | Hs | molecular function | 524 | 7.93e-173 |
intracellular | Hs | cellular component | 520 | 2.61e-171 |
cytoplasm | Hs | cellular component | 524 | 7.93e-173 |
cytosol | Hs | cellular component | 524 | 7.93e-173 |
plasma membrane | Hs | cellular component | 524 | 7.93e-173 |
cell-cell junction | Hs | cellular component | 502 | 8.96e-165 |
Rac guanyl-nucleotide exchange factor activity | Hs | molecular function | 520 | 2.61e-171 |
metal ion binding | Hs | molecular function | 524 | 7.93e-173 |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity | Hs | molecular function | 502 | 8.96e-165 |
extracellular exosome | Hs | cellular component | 520 | 2.61e-171 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
Rho guanyl-nucleotide exchange factor activity | SMART | molecular function | 5.8E-48 |
protein binding | SMART | molecular function | 3.4E-20 |
small GTPase mediated signal transduction | PANTHER | biological process | 1.1E-175 |
regulation of Rho protein signal transduction | SMART | biological process | 5.8E-48 |
intracellular signal transduction | CDD | biological process | 5.48744E-7 |