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GENE CARD

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Gene Card

Best human hits

MLH1; PMS1; PMS2

Species

P.mammillata

Unique Gene ID

Phmamm.g00009316

Gene Model ID

Phmamm.CG.MTP2014.S487.g09316

Location

S487:6148..11801

External Database Gene Card

External database links

No result

Collections

Genoscope Yasuo Villefranche

3 results

AHC0AAA13YL13

Plate: Plate_13_L13

AHC0AAA197YD11

Plate: Plate_197_D11

AHC0AAA268YJ17

Plate: Plate_268_J17

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

12 results

IPR Term Analysis Definition
HATPase_C_sf SUPERFAMILY Histidine kinase/HSP90-like ATPase superfamily
DNA_mismatch_repair_CS ProSitePatterns DNA mismatch repair, conserved site
DNA_mismatch_repair_C Pfam DNA mismatch repair protein, C-terminal
HATPase_C CDD Histidine kinase/HSP90-like ATPase
Ribosomal_S5_D2-typ_fold SUPERFAMILY Ribosomal protein S5 domain 2-type fold
DNA_mismatch_repair_fam TIGRFAM DNA mismatch repair protein family
Ribosomal_S5_D2-typ_fold_subgr Gene3D Ribosomal protein S5 domain 2-type fold, subgroup
MutL_C_sf SUPERFAMILY MutL, C-terminal domain superfamily
MutL_C SMART MutL, C-terminal, dimerisation
MutL_C Pfam MutL, C-terminal, dimerisation
HATPase_C_sf Gene3D Histidine kinase/HSP90-like ATPase superfamily
DNA_mismatch_repair_C SMART DNA mismatch repair protein, C-terminal

GOSlim

25 results

GO Term Annotation Origin Type
nucleotide binding Blast molecular function
DNA binding Orthology molecular function
chromatin binding Blast molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytosol Orthology cellular component
plasma membrane Orthology cellular component
DNA repair Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
microtubule cytoskeleton Orthology cellular component
membrane Blast cellular component
hydrolase activity Orthology molecular function
system development Orthology biological process
immune system process Orthology biological process
nucleoside-triphosphatase activity Orthology molecular function
double-stranded DNA binding Orthology molecular function
nuclear part Orthology cellular component
macromolecular complex Orthology cellular component
macromolecular complex binding Orthology molecular function
cytoplasmic part Orthology cellular component
intracellular non-membrane-bounded organelle Orthology cellular component
nuclear lumen Blast cellular component
intracellular part Blast cellular component

GO (Orthology)

24 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
DNA binding Hs molecular function
single-stranded DNA binding Hs molecular function
nuclease activity Hs molecular function
endonuclease activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
DNA repair Hs biological process
mismatch repair Hs biological process
cellular response to DNA damage stimulus Hs biological process
microtubule cytoskeleton Hs cellular component
somatic hypermutation of immunoglobulin genes Hs biological process
hydrolase activity Hs molecular function
ATPase activity Hs molecular function
mismatched DNA binding Hs molecular function
single base insertion or deletion binding Hs molecular function
MutLalpha complex Hs cellular component
MutSalpha complex binding Hs molecular function
cytoplasmic ribonucleoprotein granule Hs cellular component
response to drug Hs biological process
nucleic acid phosphodiester bond hydrolysis Hs biological process

GO (Blast)

30 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 140 1.78e-34
condensed chromosome Hs cellular component 140 1.78e-34
condensed nuclear chromosome Hs cellular component 140 1.78e-34
synaptonemal complex Hs cellular component 140 1.78e-34
male germ cell nucleus Hs cellular component 140 1.78e-34
DNA binding Hs molecular function 393 1.97e-124
chromatin binding Hs molecular function 140 1.78e-34
single-stranded DNA binding Hs molecular function 393 1.97e-124
nuclease activity Hs molecular function 393 1.97e-124
endonuclease activity Hs molecular function 393 1.97e-124
protein binding Hs molecular function 393 1.97e-124
ATP binding Hs molecular function 393 1.97e-124
nucleus Hs cellular component 393 1.97e-124
nucleoplasm Hs cellular component 393 1.97e-124
chromosome Hs cellular component 140 1.78e-34
chiasma Hs cellular component 140 1.78e-34
late recombination nodule Hs cellular component 140 1.78e-34
cytosol Hs cellular component 393 1.97e-124
plasma membrane Hs cellular component 393 1.97e-124
microtubule cytoskeleton Hs cellular component 393 1.97e-124
membrane Hs cellular component 140 1.78e-34
hydrolase activity Hs molecular function 393 1.97e-124
ATPase activity Hs molecular function 393 1.97e-124
mismatched DNA binding Hs molecular function 393 1.97e-124
guanine/thymine mispair binding Hs molecular function 140 1.78e-34
single base insertion or deletion binding Hs molecular function 393 1.97e-124
mismatch repair complex Hs cellular component 140 1.78e-34
MutLalpha complex Hs cellular component 393 1.97e-124
MutSalpha complex binding Hs molecular function 393 1.97e-124
cytoplasmic ribonucleoprotein granule Hs cellular component 393 1.97e-124

GO (InterProScan)

3 results

GO Term Analysis Type e-value
ATP binding TIGRFAM molecular function 4.3E-80
mismatch repair PANTHER biological process 2.1E-225
mismatched DNA binding TIGRFAM molecular function 4.3E-80