Gene Card
Best human hits
ARFGEF1; ARFGEF2; FBXO8
Species
Unique Gene ID
Phmamm.g00008967
Gene Model ID
Phmamm.CG.MTP2014.S458.g08967
Location
S458:14418..17880
Transcript Models and Sequences
AHC0AAA10YA06
Plate: Plate_10_A06
AHC0AAA11YK11
Plate: Plate_11_K11
AHC0AAA45YI05
Plate: Plate_45_I05
AHC0AAA72YD15
Plate: Plate_72_D15
AHC0AAA74YN03
Plate: Plate_74_N03
AHC0AAA101YG09
Plate: Plate_101_G09
AHC0AAA149YF23
Plate: Plate_149_F23
AHC0AAA83YJ18
Plate: Plate_83_J18
AHC0AAA159YL11
Plate: Plate_159_L11
AHC0AAA174YO01
Plate: Plate_174_O01
AHC0AAA178YI17
Plate: Plate_178_I17
AHC0AAA214YN17
Plate: Plate_214_N17
AHC0AAA220YP18
Plate: Plate_220_P18
AHC0AAA224YM23
Plate: Plate_224_M23
AHC0AAA256YC18
Plate: Plate_256_C18
AHC0AAA262YN11
Plate: Plate_262_N11
AHC0AAA266YD07
Plate: Plate_266_D07
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Sec7_dom | ProSiteProfiles | Sec7 domain |
F-box-like_dom_sf | SUPERFAMILY | F-box-like domain superfamily |
Sec7_dom_sf | SUPERFAMILY | Sec7 domain superfamily |
F-box_dom | ProSiteProfiles | F-box domain |
Sec7_C_sf | Gene3D | Sec7, C-terminal domain superfamily |
Sec7_dom | SMART | Sec7 domain |
Sec7_dom | Pfam | Sec7 domain |
GO Term | Annotation Origin | Type |
---|---|---|
Golgi membrane | Blast | cellular component |
binding | Blast | molecular function |
protein binding | Orthology | molecular function |
nucleus | Blast | cellular component |
nucleoplasm | Blast | cellular component |
nucleolus | Blast | cellular component |
cytoplasm | Blast | cellular component |
endosome | Blast | cellular component |
Golgi apparatus | Blast | cellular component |
microtubule organizing center | Blast | cellular component |
cytosol | Blast | cellular component |
cytoskeleton | Blast | cellular component |
membrane | Blast | cellular component |
cell junction | Blast | cellular component |
cytoplasmic vesicle | Blast | cellular component |
cell projection | Blast | cellular component |
synapse | Blast | cellular component |
perinuclear region of cytoplasm | Blast | cellular component |
regulation of molecular function | Orthology | biological process |
intracellular part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
enzyme binding | Orthology | molecular function |
molecular function regulator | Orthology | molecular function |
proteolysis | Orthology | biological process |
small GTPase mediated signal transduction | Orthology | biological process |
regulation of signal transduction | Orthology | biological process |
Golgi apparatus part | Blast | cellular component |
cell projection part | Blast | cellular component |
microtubule | Blast | cellular component |
cytoplasmic part | Blast | cellular component |
plasma membrane region | Blast | cellular component |
nuclear lumen | Blast | cellular component |
cytoskeletal protein binding | Blast | molecular function |
nuclear part | Blast | cellular component |
organelle | Blast | cellular component |
postsynapse | Blast | cellular component |
neuron part | Blast | cellular component |
receptor binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
ubiquitin ligase complex | Hs | cellular component |
guanyl-nucleotide exchange factor activity | Hs | molecular function |
ARF guanyl-nucleotide exchange factor activity | Hs | molecular function |
protein binding | Hs | molecular function |
ubiquitin-dependent protein catabolic process | Hs | biological process |
regulation of ARF protein signal transduction | Hs | biological process |
regulation of molecular function | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
Golgi membrane | Hs | cellular component | 80.5 | 2.04e-16 |
ubiquitin ligase complex | Hs | cellular component | 303 | 2.37e-102 |
guanyl-nucleotide exchange factor activity | Hs | molecular function | 303 | 2.37e-102 |
ARF guanyl-nucleotide exchange factor activity | Hs | molecular function | 303 | 2.37e-102 |
binding | Hs | molecular function | 80.5 | 2.04e-16 |
protein binding | Hs | molecular function | 303 | 2.37e-102 |
nucleus | Hs | cellular component | 79.7 | 2.99e-16 |
nucleoplasm | Hs | cellular component | 79.7 | 2.99e-16 |
nucleolus | Hs | cellular component | 79.7 | 2.99e-16 |
cytoplasm | Hs | cellular component | 80.5 | 2.04e-16 |
endosome | Hs | cellular component | 80.5 | 2.04e-16 |
Golgi apparatus | Hs | cellular component | 80.5 | 2.04e-16 |
trans-Golgi network | Hs | cellular component | 80.5 | 2.04e-16 |
microtubule organizing center | Hs | cellular component | 80.5 | 2.04e-16 |
cytosol | Hs | cellular component | 80.5 | 2.04e-16 |
cytoskeleton | Hs | cellular component | 80.5 | 2.04e-16 |
axonemal microtubule | Hs | cellular component | 80.5 | 2.04e-16 |
membrane | Hs | cellular component | 80.5 | 2.04e-16 |
nuclear matrix | Hs | cellular component | 79.7 | 2.99e-16 |
myosin binding | Hs | molecular function | 80.5 | 2.04e-16 |
cell junction | Hs | cellular component | 80.5 | 2.04e-16 |
dendrite | Hs | cellular component | 80.5 | 2.04e-16 |
small nuclear ribonucleoprotein complex | Hs | cellular component | 79.7 | 2.99e-16 |
cytoplasmic vesicle | Hs | cellular component | 80.5 | 2.04e-16 |
asymmetric synapse | Hs | cellular component | 80.5 | 2.04e-16 |
symmetric synapse | Hs | cellular component | 80.5 | 2.04e-16 |
protein kinase A regulatory subunit binding | Hs | molecular function | 80.5 | 2.04e-16 |
cell projection | Hs | cellular component | 80.5 | 2.04e-16 |
dendritic spine | Hs | cellular component | 80.5 | 2.04e-16 |
synapse | Hs | cellular component | 80.5 | 2.04e-16 |
perinuclear region of cytoplasm | Hs | cellular component | 80.5 | 2.04e-16 |
GABA receptor binding | Hs | molecular function | 80.5 | 2.04e-16 |
recycling endosome | Hs | cellular component | 80.5 | 2.04e-16 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
ARF guanyl-nucleotide exchange factor activity | SUPERFAMILY | molecular function | 4.84E-37 |
protein binding | SUPERFAMILY | molecular function | 4.58E-13 |
regulation of ARF protein signal transduction | SUPERFAMILY | biological process | 4.84E-37 |