Gene Card
Best human hits
IRAK1; IRAK4; RIPK1
Species
Unique Gene ID
Phmamm.g00008777
Gene Model ID
Phmamm.CG.MTP2014.S441.g08777
Location
S441:62566..63549
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
Prot_kinase_dom | Pfam | Protein kinase domain |
Prot_kinase_dom | SMART | Protein kinase domain |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Blast | molecular function |
magnesium ion binding | Blast | molecular function |
protein kinase activity | Blast | molecular function |
protein serine/threonine kinase activity | Blast | molecular function |
signal transducer activity | Blast | molecular function |
protein binding | Blast | molecular function |
ATP binding | Blast | molecular function |
extracellular space | Blast | cellular component |
intracellular | Blast | cellular component |
nucleus | Blast | cellular component |
cytoplasm | Blast | cellular component |
mitochondrion | Blast | cellular component |
cytosol | Blast | cellular component |
plasma membrane | Blast | cellular component |
protein phosphorylation | InterProScan | biological process |
membrane | Blast | cellular component |
kinase activity | Blast | molecular function |
transferase activity | Blast | molecular function |
ubiquitin protein ligase binding | Blast | molecular function |
identical protein binding | Blast | molecular function |
protein homodimerization activity | Blast | molecular function |
macromolecular complex binding | Blast | molecular function |
membrane raft | Blast | cellular component |
protein heterodimerization activity | Blast | molecular function |
transcription factor activity, sequence-specific DNA binding | Blast | molecular function |
enzyme regulator activity | Blast | molecular function |
intracellular signal transduction | Blast | biological process |
receptor binding | Blast | molecular function |
intracellular non-membrane-bounded organelle | Blast | cellular component |
intracellular organelle part | Blast | cellular component |
whole membrane | Blast | cellular component |
endosome | Blast | cellular component |
bounding membrane of organelle | Blast | cellular component |
plasma membrane part | Blast | cellular component |
macromolecular complex | Blast | cellular component |
integral component of plasma membrane | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 85.5 | 2.11e-19 |
magnesium ion binding | Hs | molecular function | 76.3 | 2.88e-16 |
protein kinase activity | Hs | molecular function | 85.5 | 2.11e-19 |
protein serine/threonine kinase activity | Hs | molecular function | 85.5 | 2.11e-19 |
NF-kappaB-inducing kinase activity | Hs | molecular function | 66.6 | 6.24e-13 |
signal transducer activity | Hs | molecular function | 85.5 | 2.11e-19 |
death receptor binding | Hs | molecular function | 85.5 | 2.11e-19 |
interleukin-1 receptor binding | Hs | molecular function | 76.3 | 2.88e-16 |
protein binding | Hs | molecular function | 85.5 | 2.11e-19 |
ATP binding | Hs | molecular function | 85.5 | 2.11e-19 |
extracellular space | Hs | cellular component | 76.3 | 2.88e-16 |
intracellular | Hs | cellular component | 76.3 | 2.88e-16 |
nucleus | Hs | cellular component | 76.3 | 2.88e-16 |
cytoplasm | Hs | cellular component | 85.5 | 2.11e-19 |
mitochondrion | Hs | cellular component | 85.5 | 2.11e-19 |
lipid droplet | Hs | cellular component | 66.6 | 6.24e-13 |
cytosol | Hs | cellular component | 85.5 | 2.11e-19 |
plasma membrane | Hs | cellular component | 85.5 | 2.11e-19 |
endosome membrane | Hs | cellular component | 85.5 | 2.11e-19 |
membrane | Hs | cellular component | 85.5 | 2.11e-19 |
kinase activity | Hs | molecular function | 85.5 | 2.11e-19 |
transferase activity | Hs | molecular function | 85.5 | 2.11e-19 |
heat shock protein binding | Hs | molecular function | 66.6 | 6.24e-13 |
death-inducing signaling complex | Hs | cellular component | 85.5 | 2.11e-19 |
ubiquitin protein ligase binding | Hs | molecular function | 85.5 | 2.11e-19 |
identical protein binding | Hs | molecular function | 85.5 | 2.11e-19 |
protein homodimerization activity | Hs | molecular function | 66.6 | 6.24e-13 |
receptor complex | Hs | cellular component | 85.5 | 2.11e-19 |
macromolecular complex binding | Hs | molecular function | 85.5 | 2.11e-19 |
membrane raft | Hs | cellular component | 85.5 | 2.11e-19 |
interleukin-1 receptor complex | Hs | cellular component | 66.6 | 6.24e-13 |
protein heterodimerization activity | Hs | molecular function | 66.6 | 6.24e-13 |
death domain binding | Hs | molecular function | 85.5 | 2.11e-19 |
ripoptosome | Hs | cellular component | 85.5 | 2.11e-19 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 2.1E-30 |
ATP binding | Pfam | molecular function | 2.1E-30 |
protein phosphorylation | Pfam | biological process | 2.1E-30 |