Gene Card
Best human hits
RYR1; RYR2; RYR3
Species
Unique Gene ID
Phmamm.g00001490
Gene Model ID
Phmamm.CG.MTP2014.S38.g01490
Location
S38:141846..195104
Transcript Models and Sequences
Phmamm.CG.MTP2014.S38.g01490.01.t
Phmamm.CG.MTP2014.S38.g01490.02.t
AHC0AAA89YK06
Plate: Plate_89_K06
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
ConA-like_dom_sf | SUPERFAMILY | Concanavalin A-like lectin/glucanase domain superfamily |
EF_hand_dom | ProSiteProfiles | EF-hand domain |
RyR/IP3R_RIH_dom_sf | SUPERFAMILY | RyR/IP3 receptor binding core, RIH domain superfamily |
EF-hand-dom_pair | SUPERFAMILY | EF-hand domain pair |
B30.2/SPRY | ProSiteProfiles | B30.2/SPRY domain |
Ryanodine_recept-rel | PANTHER | Ryanodine receptor-related |
MIR_motif | ProSiteProfiles | MIR motif |
MIR_dom_sf | SUPERFAMILY | Mir domain superfamily |
RIH_assoc-dom | Pfam | RyR/IP3R Homology associated domain |
MIR_motif | SMART | MIR motif |
RIH_dom | Pfam | RIH domain |
SPRY3_RyR | CDD | Ryanodine receptor, SPRY domain 3 |
Ryan_recept | PRINTS | Ryanodine receptor |
ARM-type_fold | SUPERFAMILY | Armadillo-type fold |
MIR_motif | Pfam | MIR motif |
SPRY1_RyR | CDD | Ryanodine receptor, SPRY domain 1 |
SPRY_dom | SMART | SPRY domain |
SPRY_dom | Pfam | SPRY domain |
Ins145_P3_rcpt | Pfam | Inositol 1,4,5-trisphosphate/ryanodine receptor |
Ryanodine_rcpt | Pfam | Ryanodine receptor Ryr |
Ion_trans_dom | Pfam | Ion transport domain |
Ryanrecept_TM4-6 | Pfam | Ryanodine Receptor TM 4-6 |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
response to hypoxia | Orthology | biological process |
binding | Orthology | molecular function |
calcium ion binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
calmodulin binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
cell | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
endoplasmic reticulum | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
integral component of plasma membrane | Orthology | cellular component |
ion transport | Orthology | biological process |
multicellular organism development | Orthology | biological process |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
enzyme binding | Orthology | molecular function |
protein kinase binding | Orthology | molecular function |
organelle membrane | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
identical protein binding | Orthology | molecular function |
intracellular membrane-bounded organelle | Orthology | cellular component |
metal ion binding | Orthology | molecular function |
perinuclear region of cytoplasm | Orthology | cellular component |
transmembrane transport | Orthology | biological process |
extracellular exosome | Orthology | cellular component |
organic cyclic compound binding | Orthology | molecular function |
heart development | Orthology | biological process |
anatomical structure morphogenesis | Orthology | biological process |
metal ion transport | Orthology | biological process |
intracellular signal transduction | Orthology | biological process |
cell periphery | Orthology | cellular component |
cytoplasmic part | Orthology | cellular component |
cellular process | Orthology | biological process |
endoplasmic reticulum membrane | Orthology | cellular component |
bounding membrane of organelle | Orthology | cellular component |
endoplasmic reticulum part | Orthology | cellular component |
organelle part | Orthology | cellular component |
intracellular non-membrane-bounded organelle | Orthology | cellular component |
plasma membrane part | Orthology | cellular component |
cell surface receptor signaling pathway | Orthology | biological process |
regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
response to organic substance | Orthology | biological process |
animal organ development | Orthology | biological process |
small molecule binding | Orthology | molecular function |
anion binding | Orthology | molecular function |
cell development | Orthology | biological process |
localization | Orthology | biological process |
protein homooligomerization | Orthology | biological process |
response to stimulus | Orthology | biological process |
cell-cell signaling | Orthology | biological process |
regulation of signaling | Orthology | biological process |
positive regulation of hydrolase activity | Orthology | biological process |
nucleoside-triphosphatase activity | Orthology | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 2308 | 0.0 |
protease binding | Hs | molecular function | 2308 | 0.0 |
ion channel activity | Hs | molecular function | 4321 | 0.0 |
ryanodine-sensitive calcium-release channel activity | Hs | molecular function | 4321 | 0.0 |
voltage-gated calcium channel activity | Hs | molecular function | 2308 | 0.0 |
calcium channel activity | Hs | molecular function | 4321 | 0.0 |
binding | Hs | molecular function | 2704 | 0.0 |
calcium ion binding | Hs | molecular function | 4321 | 0.0 |
protein binding | Hs | molecular function | 4321 | 0.0 |
calmodulin binding | Hs | molecular function | 4321 | 0.0 |
ATP binding | Hs | molecular function | 2308 | 0.0 |
cell | Hs | cellular component | 4321 | 0.0 |
cytoplasm | Hs | cellular component | 2308 | 0.0 |
endoplasmic reticulum | Hs | cellular component | 2704 | 0.0 |
smooth endoplasmic reticulum | Hs | cellular component | 4321 | 0.0 |
plasma membrane | Hs | cellular component | 4321 | 0.0 |
integral component of plasma membrane | Hs | cellular component | 2308 | 0.0 |
cell cortex | Hs | cellular component | 2308 | 0.0 |
junctional sarcoplasmic reticulum membrane | Hs | cellular component | 4321 | 0.0 |
terminal cisterna | Hs | cellular component | 2308 | 0.0 |
calcium-release channel activity | Hs | molecular function | 4321 | 0.0 |
membrane | Hs | cellular component | 4321 | 0.0 |
integral component of membrane | Hs | cellular component | 4321 | 0.0 |
sarcoplasmic reticulum | Hs | cellular component | 4321 | 0.0 |
enzyme binding | Hs | molecular function | 4321 | 0.0 |
protein kinase binding | Hs | molecular function | 4321 | 0.0 |
sarcomere | Hs | cellular component | 4321 | 0.0 |
Z disc | Hs | cellular component | 4321 | 0.0 |
junctional membrane complex | Hs | cellular component | 2308 | 0.0 |
T-tubule | Hs | cellular component | 2308 | 0.0 |
organelle membrane | Hs | cellular component | 2704 | 0.0 |
integral component of organelle membrane | Hs | cellular component | 2308 | 0.0 |
I band | Hs | cellular component | 2308 | 0.0 |
macromolecular complex | Hs | cellular component | 4321 | 0.0 |
sarcoplasmic reticulum membrane | Hs | cellular component | 4321 | 0.0 |
protein kinase A catalytic subunit binding | Hs | molecular function | 4321 | 0.0 |
protein kinase A regulatory subunit binding | Hs | molecular function | 4321 | 0.0 |
calcium channel complex | Hs | cellular component | 4321 | 0.0 |
identical protein binding | Hs | molecular function | 4321 | 0.0 |
intracellular membrane-bounded organelle | Hs | cellular component | 2704 | 0.0 |
protein self-association | Hs | molecular function | 4321 | 0.0 |
suramin binding | Hs | molecular function | 4321 | 0.0 |
ion channel binding | Hs | molecular function | 4321 | 0.0 |
metal ion binding | Hs | molecular function | 2308 | 0.0 |
perinuclear region of cytoplasm | Hs | cellular component | 2704 | 0.0 |
calcium-induced calcium release activity | Hs | molecular function | 4321 | 0.0 |
extracellular exosome | Hs | cellular component | 4321 | 0.0 |
organic cyclic compound binding | Hs | molecular function | 4321 | 0.0 |
ryanodine receptor complex | Hs | cellular component | 2308 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
ion channel activity | Pfam | molecular function | 3.2E-6 |
ryanodine-sensitive calcium-release channel activity | PRINTS | molecular function | 1.0E-71 |
calcium channel activity | Pfam | molecular function | 1.2E-65 |
binding | SUPERFAMILY | molecular function | 4.32E-5 |
calcium ion binding | ProSiteProfiles | molecular function | 8.627 |
protein binding | SMART | molecular function | 5.3E-31 |
ion transport | Pfam | biological process | 3.2E-6 |
calcium ion transport | PANTHER | biological process | 0.0 |
cellular calcium ion homeostasis | Pfam | biological process | 8.1E-11 |
membrane | Pfam | cellular component | 1.2E-65 |
integral component of membrane | Pfam | cellular component | 8.1E-11 |
transmembrane transport | Pfam | biological process | 3.2E-6 |
calcium ion transmembrane transport | Pfam | biological process | 1.2E-65 |