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GENE CARD

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Gene Card

Best human hits

EPS8; EPS8L1; EPS8L2

Species

P.mammillata

Unique Gene ID

Phmamm.g00007442

Gene Model ID

Phmamm.CG.MTP2014.S336.g07442

Location

S336:96289..113830

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

9 results

IPR Term Analysis Definition
SH3_domain Pfam SH3 domain
PTB/PI_dom SMART PTB/PI domain
EPS8 PANTHER Epidermal growth factor receptor kinase substrate 8
SH3-like_dom_sf SUPERFAMILY SH3-like domain superfamily
PH-like_dom_sf Gene3D PH-like domain superfamily
PTB Pfam Tensin/EPS8 phosphotyrosine-binding domain
SH3_domain SMART SH3 domain
EPS8_PTB CDD Epidermal growth factor receptor kinase substrate, phosphotyrosine-binding domain
SH3_domain ProSiteProfiles SH3 domain

GOSlim

45 results

GO Term Annotation Origin Type
actin binding Orthology molecular function
protein binding Orthology molecular function
cytoplasm Orthology cellular component
cytosol Orthology cellular component
plasma membrane Orthology cellular component
brush border Orthology cellular component
signal transduction Orthology biological process
sensory perception of sound Orthology biological process
cell proliferation Orthology biological process
positive regulation of signal transduction Orthology biological process
membrane Orthology cellular component
kinase activity Orthology molecular function
phosphorylation Orthology biological process
cell junction Orthology cellular component
vesicle Orthology cellular component
macromolecular complex Orthology cellular component
cell projection Orthology cellular component
neuron projection Orthology cellular component
synapse Orthology cellular component
regulation of molecular function Orthology biological process
extracellular exosome Orthology cellular component
enzyme binding Orthology molecular function
molecular function regulator Orthology molecular function
cell periphery Orthology cellular component
cytoplasmic part Orthology cellular component
cell surface receptor signaling pathway Orthology biological process
small GTPase mediated signal transduction Orthology biological process
cell morphogenesis Orthology biological process
mitotic cell cycle phase transition Orthology biological process
organelle Orthology cellular component
postsynapse Orthology cellular component
neuron part Orthology cellular component
integral component of plasma membrane Orthology cellular component
cell projection part Orthology cellular component
axon Orthology cellular component
organelle organization Orthology biological process
cluster of actin-based cell projections Orthology cellular component
cell projection membrane Orthology cellular component
cell leading edge Orthology cellular component
regulation of signal transduction Orthology biological process
receptor binding Orthology molecular function
macromolecular complex binding Orthology molecular function
cell adhesion molecule binding Orthology molecular function
response to organic substance Orthology biological process
cell projection assembly Orthology biological process

GO (Orthology)

49 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
actin binding Hs molecular function
SH3/SH2 adaptor activity Hs molecular function
Rho guanyl-nucleotide exchange factor activity Hs molecular function
protein binding Hs molecular function
cytoplasm Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
brush border Hs cellular component
cell cortex Hs cellular component
signal transduction Hs biological process
epidermal growth factor receptor signaling pathway Hs biological process
Rho protein signal transduction Hs biological process
sensory perception of sound Hs biological process
cell proliferation Hs biological process
adult locomotory behavior Hs biological process
regulation of cell shape Hs biological process
positive regulation of signal transduction Hs biological process
exit from mitosis Hs biological process
postsynaptic density Hs cellular component
membrane Hs cellular component
kinase activity Hs molecular function
phosphorylation Hs biological process
Rac protein signal transduction Hs biological process
NMDA selective glutamate receptor complex Hs cellular component
cell junction Hs cellular component
growth cone Hs cellular component
Rac guanyl-nucleotide exchange factor activity Hs molecular function
actin cytoskeleton reorganization Hs biological process
vesicle Hs cellular component
stereocilium Hs cellular component
stereocilium bundle Hs cellular component
stereocilium tip Hs cellular component
ruffle membrane Hs cellular component
macromolecular complex Hs cellular component
regulation of Rho protein signal transduction Hs biological process
signaling adaptor activity Hs molecular function
T cell receptor binding Hs molecular function
cell projection Hs cellular component
neuron projection Hs cellular component
synapse Hs cellular component
cadherin binding Hs molecular function
behavioral response to ethanol Hs biological process
Rac GTPase binding Hs molecular function
barbed-end actin filament capping Hs biological process
actin filament bundle assembly Hs biological process
actin crosslink formation Hs biological process
regulation of molecular function Hs biological process
extracellular exosome Hs cellular component
positive regulation of ruffle assembly Hs biological process

GO (Blast)

30 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
actin binding Hs molecular function 436 5.02e-143
SH3/SH2 adaptor activity Hs molecular function 436 5.02e-143
Rho guanyl-nucleotide exchange factor activity Hs molecular function 335 2.05e-105
protein binding Hs molecular function 436 5.02e-143
cytoplasm Hs cellular component 436 5.02e-143
cytosol Hs cellular component 335 2.05e-105
plasma membrane Hs cellular component 436 5.02e-143
brush border Hs cellular component 436 5.02e-143
cell cortex Hs cellular component 436 5.02e-143
postsynaptic density Hs cellular component 436 5.02e-143
membrane Hs cellular component 436 5.02e-143
kinase activity Hs molecular function 246 4.18e-72
NMDA selective glutamate receptor complex Hs cellular component 436 5.02e-143
cell junction Hs cellular component 436 5.02e-143
growth cone Hs cellular component 436 5.02e-143
Rac guanyl-nucleotide exchange factor activity Hs molecular function 335 2.05e-105
vesicle Hs cellular component 436 5.02e-143
stereocilium Hs cellular component 436 5.02e-143
stereocilium bundle Hs cellular component 436 5.02e-143
stereocilium tip Hs cellular component 436 5.02e-143
ruffle membrane Hs cellular component 436 5.02e-143
macromolecular complex Hs cellular component 335 2.05e-105
signaling adaptor activity Hs molecular function 436 5.02e-143
T cell receptor binding Hs molecular function 246 4.18e-72
cell projection Hs cellular component 436 5.02e-143
neuron projection Hs cellular component 436 5.02e-143
synapse Hs cellular component 436 5.02e-143
cadherin binding Hs molecular function 335 2.05e-105
Rac GTPase binding Hs molecular function 436 5.02e-143
extracellular exosome Hs cellular component 436 5.02e-143

GO (InterProScan)

5 results

GO Term Analysis Type e-value
actin binding PANTHER molecular function 8.7E-176
protein binding Pfam molecular function 3.6E-39
signaling adaptor activity PANTHER molecular function 8.7E-176
barbed-end actin filament capping PANTHER biological process 8.7E-176
actin filament bundle assembly PANTHER biological process 8.7E-176