IPR Term	Analysis	Definition
bHLH_dom	ProSiteProfiles	Myc-type, basic helix-loop-helix (bHLH) domain
HLH_DNA-bd_sf	SUPERFAMILY	Helix-loop-helix DNA-binding domain superfamily
bHLH_dom	Pfam	Myc-type, basic helix-loop-helix (bHLH) domain
Tscrpt_reg_Myc_N	Pfam	Transcription regulator Myc, N-terminal
bHLH_dom	CDD	Myc-type, basic helix-loop-helix (bHLH) domain
HLH_DNA-bd_sf	Gene3D	Helix-loop-helix DNA-binding domain superfamily
Tscrpt_reg_Myc	PRINTS	Transcription regulator Myc
bHLH_dom	SMART	Myc-type, basic helix-loop-helix (bHLH) domain

GO Term	Annotation Origin	Type
G1/S transition of mitotic cell cycle	Orthology	biological process
negative regulation of transcription from RNA polymerase II promoter	Orthology	biological process
RNA polymerase II regulatory region sequence-specific DNA binding	Blast	molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Orthology	molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
DNA binding	Orthology	molecular function
double-stranded DNA binding	Orthology	molecular function
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
transcription cofactor activity	Blast	molecular function
transcription coactivator activity	Blast	molecular function
protein binding	Orthology	molecular function
nucleus	Orthology	cellular component
nuclear envelope	Orthology	cellular component
nucleoplasm	Orthology	cellular component
nucleolus	Orthology	cellular component
cytoplasm	Orthology	cellular component
mitochondrion	Orthology	cellular component
cytosol	Orthology	cellular component
transcription, DNA-templated	Orthology	biological process
DNA-templated transcription, initiation	Orthology	biological process
regulation of transcription, DNA-templated	Orthology	biological process
regulation of transcription from RNA polymerase II promoter	Orthology	biological process
transcription from RNA polymerase II promoter	Orthology	biological process
cellular response to DNA damage stimulus	Orthology	biological process
Notch signaling pathway	Orthology	biological process
transcription factor binding	Orthology	molecular function
cell proliferation	Orthology	biological process
positive regulation of cell proliferation	Orthology	biological process
response to wounding	Orthology	biological process
regulation of gene expression	Orthology	biological process
positive regulation of gene expression	Orthology	biological process
negative regulation of gene expression	Orthology	biological process
positive regulation of cell death	Orthology	biological process
membrane	Orthology	cellular component
integral component of membrane	Orthology	cellular component
cytokine-mediated signaling pathway	Orthology	biological process
kinase binding	Orthology	molecular function
macromolecular complex	Orthology	cellular component
protein homodimerization activity	Blast	molecular function
cell projection	Blast	cellular component
negative regulation of apoptotic process	Orthology	biological process
sequence-specific DNA binding	Orthology	molecular function
macromolecular complex binding	Orthology	molecular function
positive regulation of transcription, DNA-templated	Orthology	biological process
positive regulation of transcription from RNA polymerase II promoter	Orthology	biological process
protein heterodimerization activity	Orthology	molecular function
protein dimerization activity	Orthology	molecular function
negative regulation of cell death	Orthology	biological process
intracellular signal transduction	Orthology	biological process
protein phosphorylation	Orthology	biological process
intracellular organelle part	Orthology	cellular component
intracellular non-membrane-bounded organelle	Orthology	cellular component
nuclear lumen	Orthology	cellular component
animal organ development	Orthology	biological process
anatomical structure morphogenesis	Orthology	biological process
reproductive process	Orthology	biological process
phosphorylation	Orthology	biological process
transmembrane transport	Orthology	biological process
monovalent inorganic cation transport	Orthology	biological process
regulation of cellular metabolic process	Orthology	biological process
RNA binding	Orthology	molecular function
endoplasmic reticulum	Orthology	cellular component
organic substance metabolic process	Orthology	biological process
oxidation-reduction process	Orthology	biological process
cellular metabolic process	Orthology	biological process
organelle organization	Orthology	biological process
organic substance transport	Orthology	biological process
ion transport	Orthology	biological process
cellular process	Orthology	biological process
cell	Orthology	cellular component
membrane organization	Orthology	biological process
peptidase activity, acting on L-amino acid peptides	Orthology	molecular function
brain development	Orthology	biological process
gamete generation	Orthology	biological process
response to lipid	Orthology	biological process
cellular response to organic substance	Orthology	biological process
cellular response to stress	Orthology	biological process
negative regulation of signal transduction	Orthology	biological process
endopeptidase activity	Orthology	molecular function
positive regulation of hydrolase activity	Orthology	biological process
positive regulation of apoptotic process	Orthology	biological process
response to organic substance	Orthology	biological process
cell cycle	Orthology	biological process
multicellular organism development	Orthology	biological process
cell division	Orthology	biological process
cell surface receptor signaling pathway	Orthology	biological process
cell-cell signaling	Orthology	biological process
cell development	Orthology	biological process
generation of neurons	Orthology	biological process
innate immune response	Orthology	biological process
response to hypoxia	Orthology	biological process
phosphate-containing compound metabolic process	Orthology	biological process
nuclear body	Blast	cellular component
nucleoplasm part	Blast	cellular component
nuclear part	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
G1/S transition of mitotic cell cycle	Hs	biological process
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
MAPK cascade	Hs	biological process
chromatin	Hs	cellular component
nuclear chromatin	Hs	cellular component
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Hs	molecular function
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	Hs	molecular function
cartilage condensation	Hs	biological process
ovarian follicle development	Hs	biological process
branching involved in ureteric bud morphogenesis	Hs	biological process
regulation of oxidative phosphorylation	Hs	biological process
DNA binding	Hs	molecular function
double-stranded DNA binding	Hs	molecular function
transcription factor activity, sequence-specific DNA binding	Hs	molecular function
mRNA binding	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
nuclear envelope	Hs	cellular component
nucleoplasm	Hs	cellular component
nucleolus	Hs	cellular component
cytoplasm	Hs	cellular component
mitochondrion	Hs	cellular component
rough endoplasmic reticulum	Hs	cellular component
cytosol	Hs	cellular component
glucose metabolic process	Hs	biological process
energy reserve metabolic process	Hs	biological process
chromatin remodeling	Hs	biological process
transcription, DNA-templated	Hs	biological process
DNA-templated transcription, initiation	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
regulation of transcription from RNA polymerase II promoter	Hs	biological process
transcription from RNA polymerase II promoter	Hs	biological process
amino acid transport	Hs	biological process
cellular iron ion homeostasis	Hs	biological process
cellular response to DNA damage stimulus	Hs	biological process
inner mitochondrial membrane organization	Hs	biological process
cell cycle arrest	Hs	biological process
Notch signaling pathway	Hs	biological process
regulation of mitotic cell cycle	Hs	biological process
transcription factor binding	Hs	molecular function
cell proliferation	Hs	biological process
positive regulation of cell proliferation	Hs	biological process
response to wounding	Hs	biological process
response to gamma radiation	Hs	biological process
regulation of gene expression	Hs	biological process
positive regulation of gene expression	Hs	biological process
negative regulation of gene expression	Hs	biological process
positive regulation of mitochondrial membrane potential	Hs	biological process
positive regulation of cell death	Hs	biological process
oxygen transport	Hs	biological process
membrane	Hs	cellular component
integral component of membrane	Hs	cellular component
protein deubiquitination	Hs	biological process
cytokine-mediated signaling pathway	Hs	biological process
kinase binding	Hs	molecular function
hypothalamus development	Hs	biological process
lung development	Hs	biological process
ovulation	Hs	biological process
response to estradiol	Hs	biological process
cellular response to insulin stimulus	Hs	biological process
negative regulation of stress-activated MAPK cascade	Hs	biological process
macromolecular complex	Hs	cellular component
activating transcription factor binding	Hs	molecular function
cellular response to UV	Hs	biological process
response to drug	Hs	biological process
negative regulation of apoptotic process	Hs	biological process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Hs	biological process
positive regulation of DNA binding	Hs	biological process
sequence-specific DNA binding	Hs	molecular function
nucleoplasmic reticulum	Hs	cellular component
macromolecular complex binding	Hs	molecular function
response to ethanol	Hs	biological process
positive regulation of translation	Hs	biological process
positive regulation of cell cycle	Hs	biological process
positive regulation of transcription, DNA-templated	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
protein heterodimerization activity	Hs	molecular function
protein dimerization activity	Hs	molecular function
branching morphogenesis of an epithelial tube	Hs	biological process
positive regulation of epithelial cell proliferation	Hs	biological process
chromosome organization	Hs	biological process
negative regulation of cell division	Hs	biological process
canonical Wnt signaling pathway	Hs	biological process
positive regulation of glial cell proliferation	Hs	biological process
negative regulation of cell death	Hs	biological process
repressing transcription factor binding	Hs	molecular function
response to growth factor	Hs	biological process
E-box binding	Hs	molecular function
eukaryotic initiation factor eIF2 binding	Hs	molecular function
cellular response to retinoic acid	Hs	biological process
cellular response to carbohydrate stimulus	Hs	biological process
cellular response to interferon-gamma	Hs	biological process
cellular response to interleukin-1	Hs	biological process
cellular response to epidermal growth factor stimulus	Hs	biological process
cellular response to estrogen stimulus	Hs	biological process
cellular response to organic cyclic compound	Hs	biological process
cellular response to hypoxia	Hs	biological process
positive regulation of cellular respiration	Hs	biological process
positive regulation of oxidative phosphorylation	Hs	biological process
negative regulation of reactive oxygen species metabolic process	Hs	biological process
positive regulation of response to DNA damage stimulus	Hs	biological process
positive regulation of ATP biosynthetic process	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
chromatin	Hs	cellular component	77.4	6.35e-15
nuclear chromatin	Hs	cellular component	76.6	1.06e-14
RNA polymerase II regulatory region sequence-specific DNA binding	Hs	molecular function	57.4	1.46e-09
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function	77.4	6.35e-15
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Hs	molecular function	77.4	6.35e-15
transcription factor activity, RNA polymerase II core promoter sequence-specific	Hs	molecular function	57.4	1.46e-09
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	Hs	molecular function	77.4	6.35e-15
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	Hs	molecular function	57.4	1.46e-09
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	Hs	molecular function	57.4	1.46e-09
DNA binding	Hs	molecular function	77.4	6.35e-15
double-stranded DNA binding	Hs	molecular function	76.6	1.06e-14
transcription factor activity, sequence-specific DNA binding	Hs	molecular function	77.4	6.35e-15
transcription cofactor activity	Hs	molecular function	57.4	1.46e-09
transcription coactivator activity	Hs	molecular function	57.4	1.46e-09
mRNA binding	Hs	molecular function	76.6	1.06e-14
protein binding	Hs	molecular function	77.4	6.35e-15
nucleus	Hs	cellular component	77.4	6.35e-15
nuclear envelope	Hs	cellular component	76.6	1.06e-14
nucleoplasm	Hs	cellular component	76.6	1.06e-14
nucleolus	Hs	cellular component	77.4	6.35e-15
cytoplasm	Hs	cellular component	76.6	1.06e-14
mitochondrion	Hs	cellular component	76.6	1.06e-14
rough endoplasmic reticulum	Hs	cellular component	76.6	1.06e-14
cytosol	Hs	cellular component	76.6	1.06e-14
transcription factor binding	Hs	molecular function	76.6	1.06e-14
membrane	Hs	cellular component	76.6	1.06e-14
integral component of membrane	Hs	cellular component	76.6	1.06e-14
PML body	Hs	cellular component	57.4	1.46e-09
kinase binding	Hs	molecular function	77.4	6.35e-15
dendrite	Hs	cellular component	57.4	1.46e-09
macromolecular complex	Hs	cellular component	76.6	1.06e-14
protein-DNA complex	Hs	cellular component	57.4	1.46e-09
activating transcription factor binding	Hs	molecular function	76.6	1.06e-14
protein homodimerization activity	Hs	molecular function	57.4	1.46e-09
cell projection	Hs	cellular component	57.4	1.46e-09
sequence-specific DNA binding	Hs	molecular function	76.6	1.06e-14
nucleoplasmic reticulum	Hs	cellular component	76.6	1.06e-14
macromolecular complex binding	Hs	molecular function	76.6	1.06e-14
protein heterodimerization activity	Hs	molecular function	76.6	1.06e-14
protein dimerization activity	Hs	molecular function	77.4	6.35e-15
repressing transcription factor binding	Hs	molecular function	76.6	1.06e-14
E-box binding	Hs	molecular function	76.6	1.06e-14
eukaryotic initiation factor eIF2 binding	Hs	molecular function	76.6	1.06e-14
MLL1 complex	Hs	cellular component	57.4	1.46e-09
RNA polymerase II transcription factor complex	Hs	cellular component	57.4	1.46e-09

GO Term	Analysis	Type	e-value
transcription factor activity, sequence-specific DNA binding	Pfam	molecular function	1.4E-18
nucleus	PRINTS	cellular component	2.6E-9
regulation of transcription, DNA-templated	Pfam	biological process	1.4E-18
protein dimerization activity	Gene3D	molecular function	7.1E-17