Gene Card
Best human hits
EPHA4; EPHA5; EPHB2
Species
Unique Gene ID
Phmamm.g00005695
Gene Model ID
Phmamm.CG.MTP2014.S226.g05695
Location
S226:56026..65271
Transcript Models and Sequences
Genoscope Yasuo Villefranche
2 results
AHC0AAA4YC04
Plate: Plate_4_C04
AHC0AAA268YI15
Plate: Plate_268_I15
n/a
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InterPro
18 results
| IPR Term | Analysis | Definition |
|---|---|---|
| SAM | ProSiteProfiles | Sterile alpha motif domain |
| SAM | Pfam | Sterile alpha motif domain |
| FN3_dom | Pfam | Fibronectin type III |
| FN3_dom | ProSiteProfiles | Fibronectin type III |
| Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
| Tyr_kinase_cat_dom | SMART | Tyrosine-protein kinase, catalytic domain |
| Eph_TM | Pfam | Ephrin receptor, transmembrane domain |
| SAM/pointed_sf | SUPERFAMILY | Sterile alpha motif/pointed domain superfamily |
| Ig-like_fold | Gene3D | Immunoglobulin-like fold |
| Tyr_kinase_AS | ProSitePatterns | Tyrosine-protein kinase, active site |
| FN3_dom | SMART | Fibronectin type III |
| FN3_dom | CDD | Fibronectin type III |
| Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
| SAM | SMART | Sterile alpha motif domain |
| Ser-Thr/Tyr_kinase_cat_dom | PRINTS | Serine-threonine/tyrosine-protein kinase, catalytic domain |
| Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
| FN3_sf | SUPERFAMILY | Fibronectin type III superfamily |
| Ser-Thr/Tyr_kinase_cat_dom | Pfam | Serine-threonine/tyrosine-protein kinase, catalytic domain |
GOSlim
50 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| nucleotide binding | Blast | molecular function |
| protein kinase activity | Blast | molecular function |
| receptor binding | Blast | molecular function |
| protein binding | Blast | molecular function |
| ATP binding | Blast | molecular function |
| extracellular region | Blast | cellular component |
| nucleus | Blast | cellular component |
| cytoplasm | Blast | cellular component |
| endosome | Blast | cellular component |
| early endosome | Blast | cellular component |
| endoplasmic reticulum | Blast | cellular component |
| Golgi apparatus | Blast | cellular component |
| cytosol | Blast | cellular component |
| plasma membrane | Blast | cellular component |
| integral component of plasma membrane | Blast | cellular component |
| adherens junction | Blast | cellular component |
| protein phosphorylation | InterProScan | biological process |
| axon guidance | Blast | biological process |
| cell surface | Blast | cellular component |
| membrane | Blast | cellular component |
| integral component of membrane | Blast | cellular component |
| kinase activity | Blast | molecular function |
| transferase activity | Blast | molecular function |
| cell junction | Blast | cellular component |
| axon | Blast | cellular component |
| identical protein binding | Blast | molecular function |
| cell projection | Blast | cellular component |
| neuronal cell body | Blast | cellular component |
| cell body | Blast | cellular component |
| macromolecular complex binding | Blast | molecular function |
| synapse | Blast | cellular component |
| postsynaptic membrane | Blast | cellular component |
| perinuclear region of cytoplasm | Blast | cellular component |
| cell periphery | Blast | cellular component |
| postsynapse | Blast | cellular component |
| binding | Blast | molecular function |
| transmembrane signaling receptor activity | Blast | molecular function |
| cell surface receptor signaling pathway | Blast | biological process |
| whole membrane | Blast | cellular component |
| mitochondrial membrane | Blast | cellular component |
| bounding membrane of organelle | Blast | cellular component |
| plasma membrane part | Blast | cellular component |
| organelle | Blast | cellular component |
| neuron part | Blast | cellular component |
| plasma membrane region | Blast | cellular component |
| cytoskeletal part | Blast | cellular component |
| intracellular organelle part | Blast | cellular component |
| cell projection part | Blast | cellular component |
| synapse part | Blast | cellular component |
| protein kinase binding | Blast | molecular function |
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
58 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| nucleotide binding | Hs | molecular function | 556 | 0.0 |
| amyloid-beta binding | Hs | molecular function | 556 | 0.0 |
| protein kinase activity | Hs | molecular function | 556 | 0.0 |
| protein tyrosine kinase activity | Hs | molecular function | 556 | 0.0 |
| transmembrane receptor protein tyrosine kinase activity | Hs | molecular function | 556 | 0.0 |
| receptor activity | Hs | molecular function | 556 | 0.0 |
| ephrin receptor activity | Hs | molecular function | 556 | 0.0 |
| GPI-linked ephrin receptor activity | Hs | molecular function | 553 | 0.0 |
| transmembrane-ephrin receptor activity | Hs | molecular function | 556 | 0.0 |
| receptor binding | Hs | molecular function | 556 | 0.0 |
| protein binding | Hs | molecular function | 556 | 0.0 |
| ATP binding | Hs | molecular function | 556 | 0.0 |
| extracellular region | Hs | cellular component | 556 | 0.0 |
| nucleus | Hs | cellular component | 556 | 0.0 |
| cytoplasm | Hs | cellular component | 551 | 0.0 |
| mitochondrial outer membrane | Hs | cellular component | 551 | 0.0 |
| endosome | Hs | cellular component | 551 | 0.0 |
| early endosome | Hs | cellular component | 551 | 0.0 |
| endoplasmic reticulum | Hs | cellular component | 551 | 0.0 |
| rough endoplasmic reticulum | Hs | cellular component | 553 | 0.0 |
| Golgi apparatus | Hs | cellular component | 551 | 0.0 |
| cytosol | Hs | cellular component | 556 | 0.0 |
| plasma membrane | Hs | cellular component | 556 | 0.0 |
| integral component of plasma membrane | Hs | cellular component | 556 | 0.0 |
| adherens junction | Hs | cellular component | 553 | 0.0 |
| axon guidance receptor activity | Hs | molecular function | 556 | 0.0 |
| external side of plasma membrane | Hs | cellular component | 553 | 0.0 |
| cell surface | Hs | cellular component | 551 | 0.0 |
| postsynaptic density | Hs | cellular component | 551 | 0.0 |
| membrane | Hs | cellular component | 556 | 0.0 |
| integral component of membrane | Hs | cellular component | 556 | 0.0 |
| kinase activity | Hs | molecular function | 556 | 0.0 |
| transferase activity | Hs | molecular function | 556 | 0.0 |
| cell junction | Hs | cellular component | 551 | 0.0 |
| filopodium | Hs | cellular component | 551 | 0.0 |
| axon | Hs | cellular component | 556 | 0.0 |
| dendrite | Hs | cellular component | 556 | 0.0 |
| neuromuscular junction | Hs | cellular component | 551 | 0.0 |
| early endosome membrane | Hs | cellular component | 551 | 0.0 |
| PH domain binding | Hs | molecular function | 551 | 0.0 |
| identical protein binding | Hs | molecular function | 556 | 0.0 |
| cell projection | Hs | cellular component | 556 | 0.0 |
| neuronal cell body | Hs | cellular component | 556 | 0.0 |
| dendritic spine | Hs | cellular component | 551 | 0.0 |
| dendritic shaft | Hs | cellular component | 551 | 0.0 |
| perikaryon | Hs | cellular component | 551 | 0.0 |
| axon terminus | Hs | cellular component | 551 | 0.0 |
| axonal growth cone | Hs | cellular component | 551 | 0.0 |
| cell body | Hs | cellular component | 551 | 0.0 |
| macromolecular complex binding | Hs | molecular function | 556 | 0.0 |
| synapse | Hs | cellular component | 551 | 0.0 |
| postsynaptic membrane | Hs | cellular component | 551 | 0.0 |
| ephrin receptor binding | Hs | molecular function | 551 | 0.0 |
| perinuclear region of cytoplasm | Hs | cellular component | 553 | 0.0 |
| cell periphery | Hs | cellular component | 553 | 0.0 |
| DH domain binding | Hs | molecular function | 551 | 0.0 |
| postsynapse | Hs | cellular component | 556 | 0.0 |
| protein tyrosine kinase binding | Hs | molecular function | 551 | 0.0 |
GO (InterProScan)
5 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein kinase activity | Pfam | molecular function | 5.2E-93 |
| protein tyrosine kinase activity | SMART | molecular function | 6.9E-129 |
| protein binding | SUPERFAMILY | molecular function | 1.82E-33 |
| ATP binding | ProSiteProfiles | molecular function | 39.213 |
| protein phosphorylation | SMART | biological process | 6.9E-129 |
