Gene Card
Best human hits
DNMT1; KDM2B; KMT2B
Species
Unique Gene ID
Phmamm.g00016352
Gene Model ID
Phmamm.CG.MTP2014.S2196.g16352
Location
S2196:3990..10112
Transcript Models and Sequences
AHC0AAA5YI18
Plate: Plate_5_I18
AHC0AAA183YE19
Plate: Plate_183_E19
AHC0AAA216YK05
Plate: Plate_216_K05
AHC0AAA261YB06
Plate: Plate_261_B06
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Znf_CXXC | ProSiteProfiles | Zinc finger, CXXC-type |
DNMT1-like | PIRSF | DNA (cytosine-5)-methyltransferase 1-like |
C5_MeTfrase | ProSiteProfiles | C-5 cytosine methyltransferase |
BAH_dom | SMART | Bromo adjacent homology (BAH) domain |
BAH_dom | Pfam | Bromo adjacent homology (BAH) domain |
BAH_dom | ProSiteProfiles | Bromo adjacent homology (BAH) domain |
C5_MeTfrase | PRINTS | C-5 cytosine methyltransferase |
SAM-dependent_MTases | SUPERFAMILY | S-adenosyl-L-methionine-dependent methyltransferase |
C5_meth_CS | ProSitePatterns | DNA methylase, C-5 cytosine-specific, conserved site |
Cytosine_MeTrfase1_RFD | Pfam | DNA (cytosine-5)-methyltransferase 1, replication foci domain |
C5_DNA_meth_AS | ProSitePatterns | DNA methylase, C-5 cytosine-specific, active site |
C5_MeTfrase | Pfam | C-5 cytosine methyltransferase |
Znf_CXXC | Pfam | Zinc finger, CXXC-type |
GO Term | Annotation Origin | Type |
---|---|---|
negative regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
RNA polymerase II core promoter proximal region sequence-specific DNA binding | Blast | molecular function |
DNA binding | Orthology | molecular function |
chromatin binding | Orthology | molecular function |
transcription factor activity, sequence-specific DNA binding | Blast | molecular function |
RNA binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
nucleolus | Blast | cellular component |
transcription, DNA-templated | Orthology | biological process |
regulation of transcription, DNA-templated | Orthology | biological process |
zinc ion binding | Orthology | molecular function |
regulation of gene expression | Orthology | biological process |
positive regulation of gene expression | Orthology | biological process |
transferase activity | Orthology | molecular function |
regulation of cell proliferation | Orthology | biological process |
negative regulation of transcription, DNA-templated | Orthology | biological process |
metal ion binding | Orthology | molecular function |
oxidation-reduction process | Blast | biological process |
intracellular organelle part | Orthology | cellular component |
intracellular non-membrane-bounded organelle | Orthology | cellular component |
DNA metabolic process | Orthology | biological process |
organelle organization | Orthology | biological process |
small GTPase mediated signal transduction | Orthology | biological process |
metabolic process | Orthology | biological process |
sequence-specific DNA binding | Orthology | molecular function |
nucleotide binding | Orthology | molecular function |
negative regulation of gene expression | Orthology | biological process |
cellular process | Orthology | biological process |
multicellular organism development | Orthology | biological process |
cellular protein modification process | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
catalytic activity | Blast | molecular function |
nuclear part | Blast | cellular component |
macromolecular complex | Blast | cellular component |
nucleoplasm part | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
heterochromatin | Hs | cellular component | 1099 | 0.0 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding | Hs | molecular function | 59.3 | 1.51e-08 |
DNA binding | Hs | molecular function | 1099 | 0.0 |
chromatin binding | Hs | molecular function | 1099 | 0.0 |
transcription factor activity, sequence-specific DNA binding | Hs | molecular function | 56.2 | 1.37e-07 |
RNA binding | Hs | molecular function | 1099 | 0.0 |
DNA (cytosine-5-)-methyltransferase activity | Hs | molecular function | 1099 | 0.0 |
protein binding | Hs | molecular function | 1099 | 0.0 |
nucleus | Hs | cellular component | 1099 | 0.0 |
nucleoplasm | Hs | cellular component | 1099 | 0.0 |
replication fork | Hs | cellular component | 1099 | 0.0 |
pericentric heterochromatin | Hs | cellular component | 1099 | 0.0 |
nucleolus | Hs | cellular component | 59.3 | 1.51e-08 |
methyltransferase activity | Hs | molecular function | 1099 | 0.0 |
zinc ion binding | Hs | molecular function | 1099 | 0.0 |
methyl-CpG binding | Hs | molecular function | 1099 | 0.0 |
DNA-methyltransferase activity | Hs | molecular function | 1099 | 0.0 |
oxidoreductase activity | Hs | molecular function | 59.3 | 1.51e-08 |
transferase activity | Hs | molecular function | 1099 | 0.0 |
histone-lysine N-methyltransferase activity | Hs | molecular function | 56.2 | 1.37e-07 |
rRNA binding | Hs | molecular function | 59.3 | 1.51e-08 |
PcG protein complex | Hs | cellular component | 59.3 | 1.51e-08 |
histone demethylase activity | Hs | molecular function | 59.3 | 1.51e-08 |
histone methyltransferase complex | Hs | cellular component | 56.2 | 1.37e-07 |
histone methyltransferase activity (H3-K4 specific) | Hs | molecular function | 56.2 | 1.37e-07 |
metal ion binding | Hs | molecular function | 1099 | 0.0 |
dioxygenase activity | Hs | molecular function | 59.3 | 1.51e-08 |
histone demethylase activity (H3-K36 specific) | Hs | molecular function | 59.3 | 1.51e-08 |
promoter-specific chromatin binding | Hs | molecular function | 1099 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
DNA binding | Pfam | molecular function | 3.1E-14 |
chromatin binding | SMART | molecular function | 2.8E-24 |
DNA (cytosine-5-)-methyltransferase activity | PIRSF | molecular function | 9.8E-263 |
nucleus | PIRSF | cellular component | 9.8E-263 |
methyltransferase activity | Pfam | molecular function | 4.2E-18 |
zinc ion binding | Pfam | molecular function | 3.1E-14 |
C-5 methylation of cytosine | PIRSF | biological process | 9.8E-263 |