Gene Card
Best human hits
EPB41L4B; TLN1; TLN2
Species
Unique Gene ID
Phmamm.g00016103
Gene Model ID
Phmamm.CG.MTP2014.S2045.g16103
Location
S2045:7558..23443
Transcript Models and Sequences
AHC0AAA16YB19
Plate: Plate_16_B19
AHC0AAA259YD01
Plate: Plate_259_D01
n/a
You can Right Mouse Click on internal nodes, leaves and outside the tree to see multiple options adapted to your selection.
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see how you can interact with this tree
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Vinculin-bd_dom | Pfam | Vinculin-binding site-containing domain |
I/LWEQ_dom_sf | SUPERFAMILY | I/LWEQ domain superfamily |
PH-like_dom_sf | Gene3D | PH-like domain superfamily |
FERM_N | Pfam | FERM, N-terminal |
Alpha-catenin/vinculin-like_sf | SUPERFAMILY | Alpha-catenin/vinculin-like superfamily |
FERM_domain | ProSiteProfiles | FERM domain |
Talin_cent | Pfam | Talin, central |
ILWEQ_dom | SMART | I/LWEQ domain |
FERM_central | CDD | FERM central domain |
Band_41_domain | SMART | Band 4.1 domain |
FERM_f0 | Pfam | Talin, N-terminal F0 domain |
Talin_cent_sf | SUPERFAMILY | Talin, central domain superfamily |
FERM_2 | SUPERFAMILY | FERM superfamily, second domain |
FERM/acyl-CoA-bd_prot_sf | Gene3D | FERM/acyl-CoA-binding protein superfamily |
FERM_central | Pfam | FERM central domain |
GO Term | Annotation Origin | Type |
---|---|---|
actin binding | Orthology | molecular function |
integrin binding | Orthology | molecular function |
structural molecule activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
extracellular region | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
cytoskeleton | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
focal adhesion | Orthology | cellular component |
cell adhesion | Orthology | biological process |
cytoskeletal protein binding | Orthology | molecular function |
cell surface | Orthology | cellular component |
membrane | Orthology | cellular component |
cell junction | Orthology | cellular component |
cell projection | Orthology | cellular component |
apical part of cell | Blast | cellular component |
synapse | Orthology | cellular component |
actin filament binding | Orthology | molecular function |
extracellular exosome | Orthology | cellular component |
plasma membrane region | Orthology | cellular component |
cell leading edge | Orthology | cellular component |
anion binding | Orthology | molecular function |
membrane organization | Orthology | biological process |
organelle organization | Orthology | biological process |
cell | Orthology | cellular component |
cellular protein localization | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
cell projection membrane | Orthology | cellular component |
cell adhesion molecule binding | Orthology | molecular function |
blood coagulation | Orthology | biological process |
cellular process | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
ruffle | Hs | cellular component |
phosphatidylserine binding | Hs | molecular function |
platelet degranulation | Hs | biological process |
actin binding | Hs | molecular function |
integrin binding | Hs | molecular function |
structural molecule activity | Hs | molecular function |
structural constituent of cytoskeleton | Hs | molecular function |
protein binding | Hs | molecular function |
extracellular region | Hs | cellular component |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
cytoskeleton | Hs | cellular component |
plasma membrane | Hs | cellular component |
focal adhesion | Hs | cellular component |
muscle contraction | Hs | biological process |
cytoskeletal anchoring at plasma membrane | Hs | biological process |
cell-cell junction assembly | Hs | biological process |
cell-substrate junction assembly | Hs | biological process |
cell adhesion | Hs | biological process |
integrin-mediated signaling pathway | Hs | biological process |
cell surface | Hs | cellular component |
actin cytoskeleton | Hs | cellular component |
membrane | Hs | cellular component |
viral process | Hs | biological process |
vinculin binding | Hs | molecular function |
cell junction | Hs | cellular component |
LIM domain binding | Hs | molecular function |
cortical actin cytoskeleton organization | Hs | biological process |
ruffle membrane | Hs | cellular component |
phosphatidylinositol binding | Hs | molecular function |
cell projection | Hs | cellular component |
synapse | Hs | cellular component |
cadherin binding | Hs | molecular function |
actin filament binding | Hs | molecular function |
extracellular exosome | Hs | cellular component |
platelet aggregation | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
ruffle | Hs | cellular component | 1601 | 0.0 |
phosphatidylserine binding | Hs | molecular function | 1601 | 0.0 |
actin binding | Hs | molecular function | 1601 | 0.0 |
integrin binding | Hs | molecular function | 1601 | 0.0 |
structural molecule activity | Hs | molecular function | 1593 | 0.0 |
structural constituent of cytoskeleton | Hs | molecular function | 1601 | 0.0 |
protein binding | Hs | molecular function | 1601 | 0.0 |
extracellular region | Hs | cellular component | 1601 | 0.0 |
cytoplasm | Hs | cellular component | 1601 | 0.0 |
cytosol | Hs | cellular component | 1601 | 0.0 |
cytoskeleton | Hs | cellular component | 1601 | 0.0 |
plasma membrane | Hs | cellular component | 1601 | 0.0 |
bicellular tight junction | Hs | cellular component | 59.7 | 1.28e-08 |
focal adhesion | Hs | cellular component | 1601 | 0.0 |
cytoskeletal protein binding | Hs | molecular function | 59.7 | 1.28e-08 |
cell surface | Hs | cellular component | 1601 | 0.0 |
actin cytoskeleton | Hs | cellular component | 1593 | 0.0 |
membrane | Hs | cellular component | 1601 | 0.0 |
vinculin binding | Hs | molecular function | 1601 | 0.0 |
cell junction | Hs | cellular component | 1601 | 0.0 |
LIM domain binding | Hs | molecular function | 1601 | 0.0 |
ruffle membrane | Hs | cellular component | 1601 | 0.0 |
phosphatidylinositol binding | Hs | molecular function | 1601 | 0.0 |
cell projection | Hs | cellular component | 1601 | 0.0 |
apical part of cell | Hs | cellular component | 59.7 | 1.28e-08 |
synapse | Hs | cellular component | 1593 | 0.0 |
cadherin binding | Hs | molecular function | 1601 | 0.0 |
actin filament binding | Hs | molecular function | 1601 | 0.0 |
extracellular exosome | Hs | cellular component | 1601 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
ruffle | Pfam | cellular component | 3.1E-54 |
actin binding | SUPERFAMILY | molecular function | 1.44E-44 |
structural constituent of cytoskeleton | Pfam | molecular function | 3.1E-54 |
cytoskeleton | ProSiteProfiles | cellular component | 45.541 |
focal adhesion | Pfam | cellular component | 3.1E-54 |
cytoskeletal anchoring at plasma membrane | Pfam | biological process | 3.1E-54 |
cell adhesion | SUPERFAMILY | biological process | 2.82E-32 |
actin filament binding | SUPERFAMILY | molecular function | 2.82E-32 |