Gene Card
Best human hits
ACVR1B; ACVR1C; TGFBR1
Species
Unique Gene ID
Phmamm.g00004838
Gene Model ID
Phmamm.CG.MTP2014.S179.g04838
Location
S179:192807..202804
Transcript Models and Sequences
AHC0AAA13YA01
Plate: Plate_13_A01
AHC0AAA41YI23
Plate: Plate_41_I23
AHC0AAA60YE16
Plate: Plate_60_E16
AHC0AAA73YD10
Plate: Plate_73_D10
AHC0AAA77YP16
Plate: Plate_77_P16
AHC0AAA104YK14
Plate: Plate_104_K14
AHC0AAA122YB02
Plate: Plate_122_B02
AHC0AAA128YP13
Plate: Plate_128_P13
AHC0AAA152YE06
Plate: Plate_152_E06
AHC0AAA93YK15
Plate: Plate_93_K15
AHC0AAA94YI03
Plate: Plate_94_I03
AHC0AAA162YM20
Plate: Plate_162_M20
AHC0AAA174YG05
Plate: Plate_174_G05
AHC0AAA197YI11
Plate: Plate_197_I11
AHC0AAA197YO08
Plate: Plate_197_O08
AHC0AAA208YD12
Plate: Plate_208_D12
AHC0AAA208YL23
Plate: Plate_208_L23
AHC0AAA219YB08
Plate: Plate_219_B08
AHC0AAA242YA05
Plate: Plate_242_A05
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
GS_dom | ProSiteProfiles | GS domain |
Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
Prot_kinase_dom | SMART | Protein kinase domain |
TGFB_receptor | PANTHER | Ser/Thr protein kinase, TGFB receptor |
Prot_kinase_dom | Pfam | Protein kinase domain |
GS_dom | SMART | GS domain |
Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
GS_dom | Pfam | GS domain |
GO Term | Annotation Origin | Type |
---|---|---|
G1/S transition of mitotic cell cycle | Orthology | biological process |
nucleotide binding | Orthology | molecular function |
angiogenesis | Orthology | biological process |
protein kinase activity | Orthology | molecular function |
protein serine/threonine kinase activity | Orthology | molecular function |
receptor binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
cell | Orthology | cellular component |
endosome | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
integral component of plasma membrane | Orthology | cellular component |
regulation of transcription, DNA-templated | Orthology | biological process |
protein phosphorylation | Orthology | biological process |
apoptotic process | Orthology | biological process |
signal transduction | Orthology | biological process |
central nervous system development | Orthology | biological process |
heart development | Orthology | biological process |
positive regulation of cell proliferation | Orthology | biological process |
regulation of signal transduction | Orthology | biological process |
cell surface | Orthology | cellular component |
regulation of gene expression | Orthology | biological process |
positive regulation of gene expression | Orthology | biological process |
negative regulation of gene expression | Orthology | biological process |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
kinase activity | Orthology | molecular function |
phosphorylation | Orthology | biological process |
transferase activity | Orthology | molecular function |
cell junction | Orthology | cellular component |
cell differentiation | Orthology | biological process |
ubiquitin protein ligase binding | Orthology | molecular function |
intracellular signal transduction | Orthology | biological process |
wound healing | Orthology | biological process |
positive regulation of apoptotic process | Orthology | biological process |
negative regulation of apoptotic process | Orthology | biological process |
intracellular membrane-bounded organelle | Orthology | cellular component |
membrane raft | Orthology | cellular component |
positive regulation of transcription, DNA-templated | Orthology | biological process |
positive regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
protein autophosphorylation | Orthology | biological process |
metal ion binding | Orthology | molecular function |
cell motility | Orthology | biological process |
extracellular exosome | Orthology | cellular component |
positive regulation of catalytic activity | Orthology | biological process |
positive regulation of signal transduction | Orthology | biological process |
system development | Orthology | biological process |
animal organ development | Orthology | biological process |
anatomical structure morphogenesis | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
transmembrane signaling receptor activity | Orthology | molecular function |
cellular response to organic substance | Orthology | biological process |
cell migration | Orthology | biological process |
gamete generation | Orthology | biological process |
reproductive process | Orthology | biological process |
response to organic substance | Orthology | biological process |
multicellular organism development | Orthology | biological process |
macromolecular complex binding | Orthology | molecular function |
peptidase activity, acting on L-amino acid peptides | Orthology | molecular function |
extracellular matrix organization | Orthology | biological process |
cellular component organization | Orthology | biological process |
negative regulation of signal transduction | Orthology | biological process |
protein ubiquitination | Orthology | biological process |
regulation of cellular metabolic process | Orthology | biological process |
macromolecular complex | Orthology | cellular component |
endopeptidase activity | Orthology | molecular function |
positive regulation of hydrolase activity | Orthology | biological process |
regulation of molecular function | Orthology | biological process |
immune system process | Orthology | biological process |
protein transport | Orthology | biological process |
cell-cell signaling | Orthology | biological process |
neuron differentiation | Orthology | biological process |
blood vessel morphogenesis | Orthology | biological process |
cell projection assembly | Orthology | biological process |
organelle organization | Orthology | biological process |
anatomical structure development | Orthology | biological process |
regulation of cell proliferation | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 452 | 7.59e-157 |
protein kinase activity | Hs | molecular function | 452 | 7.59e-157 |
protein serine/threonine kinase activity | Hs | molecular function | 452 | 7.59e-157 |
transmembrane receptor protein serine/threonine kinase activity | Hs | molecular function | 452 | 7.59e-157 |
signal transducer, downstream of receptor, with serine/threonine kinase activity | Hs | molecular function | 452 | 7.59e-157 |
transforming growth factor beta-activated receptor activity | Hs | molecular function | 452 | 7.59e-157 |
transforming growth factor beta receptor activity, type I | Hs | molecular function | 452 | 7.59e-157 |
signal transducer activity, downstream of receptor | Hs | molecular function | 452 | 7.59e-157 |
receptor binding | Hs | molecular function | 452 | 7.59e-157 |
type II transforming growth factor beta receptor binding | Hs | molecular function | 452 | 7.59e-157 |
protein binding | Hs | molecular function | 452 | 7.59e-157 |
ATP binding | Hs | molecular function | 452 | 7.59e-157 |
cell | Hs | cellular component | 452 | 7.59e-157 |
endosome | Hs | cellular component | 452 | 7.59e-157 |
cytosol | Hs | cellular component | 416 | 4.68e-142 |
plasma membrane | Hs | cellular component | 452 | 7.59e-157 |
integral component of plasma membrane | Hs | cellular component | 416 | 4.68e-142 |
bicellular tight junction | Hs | cellular component | 452 | 7.59e-157 |
cell surface | Hs | cellular component | 452 | 7.59e-157 |
membrane | Hs | cellular component | 452 | 7.59e-157 |
integral component of membrane | Hs | cellular component | 452 | 7.59e-157 |
kinase activity | Hs | molecular function | 452 | 7.59e-157 |
activin receptor activity, type I | Hs | molecular function | 430 | 3.24e-148 |
transferase activity | Hs | molecular function | 452 | 7.59e-157 |
activin-activated receptor activity | Hs | molecular function | 416 | 4.68e-142 |
growth factor binding | Hs | molecular function | 452 | 7.59e-157 |
cell junction | Hs | cellular component | 452 | 7.59e-157 |
ubiquitin protein ligase binding | Hs | molecular function | 416 | 4.68e-142 |
inhibin binding | Hs | molecular function | 416 | 4.68e-142 |
nodal binding | Hs | molecular function | 430 | 3.24e-148 |
intracellular membrane-bounded organelle | Hs | cellular component | 452 | 7.59e-157 |
receptor complex | Hs | cellular component | 452 | 7.59e-157 |
membrane raft | Hs | cellular component | 452 | 7.59e-157 |
SMAD binding | Hs | molecular function | 452 | 7.59e-157 |
metal ion binding | Hs | molecular function | 452 | 7.59e-157 |
activin receptor complex | Hs | cellular component | 430 | 3.24e-148 |
activin binding | Hs | molecular function | 416 | 4.68e-142 |
transforming growth factor beta binding | Hs | molecular function | 452 | 7.59e-157 |
transforming growth factor beta receptor complex | Hs | cellular component | 452 | 7.59e-157 |
extracellular exosome | Hs | cellular component | 416 | 4.68e-142 |
I-SMAD binding | Hs | molecular function | 452 | 7.59e-157 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 1.7E-31 |
transmembrane receptor protein serine/threonine kinase activity | PANTHER | molecular function | 8.1E-158 |
signal transducer, downstream of receptor, with serine/threonine kinase activity | PANTHER | molecular function | 8.1E-158 |
ATP binding | PANTHER | molecular function | 8.1E-158 |
protein phosphorylation | Pfam | biological process | 1.7E-31 |
transmembrane receptor protein serine/threonine kinase signaling pathway | PANTHER | biological process | 8.1E-158 |
membrane | PANTHER | cellular component | 8.1E-158 |