IPR Term	Analysis	Definition
BCKDH_E1-a	PANTHER	2-oxoisovalerate dehydrogenase subunit alpha
THDP-binding	SUPERFAMILY	Thiamin diphosphate-binding fold
DH_E1	Pfam	Dehydrogenase, E1 component

GO Term	Annotation Origin	Type
protein binding	Orthology	molecular function
nucleus	Blast	cellular component
nucleolus	Blast	cellular component
mitochondrion	Orthology	cellular component
mitochondrial matrix	Orthology	cellular component
metabolic process	Orthology	biological process
myelin sheath	Blast	cellular component
intracellular membrane-bounded organelle	Blast	cellular component
metal ion binding	Orthology	molecular function
oxidation-reduction process	Orthology	biological process
catalytic activity	Orthology	molecular function
macromolecular complex	Orthology	cellular component
transferase activity	Blast	molecular function
phosphate-containing compound metabolic process	Blast	biological process
amide biosynthetic process	Blast	biological process
cytoplasmic part	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
alpha-ketoacid dehydrogenase activity	Hs	molecular function
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity	Hs	molecular function
protein binding	Hs	molecular function
mitochondrion	Hs	cellular component
mitochondrial matrix	Hs	cellular component
mitochondrial alpha-ketoglutarate dehydrogenase complex	Hs	cellular component
metabolic process	Hs	biological process
branched-chain amino acid catabolic process	Hs	biological process
oxidoreductase activity	Hs	molecular function
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	Hs	molecular function
carboxy-lyase activity	Hs	molecular function
metal ion binding	Hs	molecular function
oxidation-reduction process	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
alpha-ketoacid dehydrogenase activity	Hs	molecular function	525	0.0
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity	Hs	molecular function	525	0.0
pyruvate dehydrogenase activity	Hs	molecular function	114	6.61e-28
pyruvate dehydrogenase (acetyl-transferring) activity	Hs	molecular function	114	6.61e-28
protein binding	Hs	molecular function	510	0.0
nucleus	Hs	cellular component	114	6.61e-28
nucleolus	Hs	cellular component	114	6.61e-28
mitochondrion	Hs	cellular component	510	0.0
mitochondrial matrix	Hs	cellular component	510	0.0
mitochondrial alpha-ketoglutarate dehydrogenase complex	Hs	cellular component	510	0.0
oxidoreductase activity	Hs	molecular function	510	0.0
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	Hs	molecular function	525	0.0
carboxy-lyase activity	Hs	molecular function	510	0.0
pyruvate dehydrogenase (NAD+) activity	Hs	molecular function	114	6.61e-28
myelin sheath	Hs	cellular component	114	6.61e-28
intracellular membrane-bounded organelle	Hs	cellular component	114	6.61e-28
pyruvate dehydrogenase complex	Hs	cellular component	114	6.61e-28
metal ion binding	Hs	molecular function	510	0.0

GO Term	Analysis	Type	e-value
alpha-ketoacid dehydrogenase activity	PANTHER	molecular function	1.0E-190
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity	PANTHER	molecular function	1.0E-190
metabolic process	Pfam	biological process	9.4E-96
branched-chain amino acid catabolic process	PANTHER	biological process	1.0E-190
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	Pfam	molecular function	9.4E-96