Gene Card
Best human hits
PLCB1; PLCB2; PLCB3
Species
Unique Gene ID
Phmamm.g00004785
Gene Model ID
Phmamm.CG.MTP2014.S177.g04785
Location
S177:80288..107583
Transcript Models and Sequences
Phmamm.CG.MTP2014.S177.g04785.01.t
Phmamm.CG.MTP2014.S177.g04785.02.t
AHC0AAA43YG24
Plate: Plate_43_G24
AHC0AAA58YH04
Plate: Plate_58_H04
AHC0AAA222YD12
Plate: Plate_222_D12
AHC0AAA240YI11
Plate: Plate_240_I11
n/a
You can Right Mouse Click on internal nodes, leaves and outside the tree to see multiple options adapted to your selection.
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see how you can interact with this tree
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
PLC-like_Pdiesterase_TIM-brl | SUPERFAMILY | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily |
PLipase_C_Pinositol-sp_Y | SMART | Phospholipase C, phosphatidylinositol-specific, Y domain |
PLipase_C_Pinositol-sp_Y | ProSiteProfiles | Phospholipase C, phosphatidylinositol-specific, Y domain |
C2_domain_sf | Gene3D | C2 domain superfamily |
PLC-like_Pdiesterase_TIM-brl | Gene3D | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily |
C2_dom | SMART | C2 domain |
C2_dom | ProSiteProfiles | C2 domain |
PLC-beta_C | Pfam | Phospholipase C-beta, C-terminal domain |
PLipase_C_Pinositol-sp_Y | Pfam | Phospholipase C, phosphatidylinositol-specific, Y domain |
PI-PLC_fam | PRINTS | Phosphoinositide phospholipase C family |
PI-PLC_fam | PANTHER | Phosphoinositide phospholipase C family |
PLC-beta | PIRSF | Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta |
PLipase_C_PInositol-sp_X_dom | SMART | Phosphatidylinositol-specific phospholipase C, X domain |
PLC-beta_PH | CDD | PLC-beta, PH domain |
PLipase_C_PInositol-sp_X_dom | Pfam | Phosphatidylinositol-specific phospholipase C, X domain |
PLC_EF-hand-like | Pfam | Phosphoinositide-specific phospholipase C, EF-hand-like domain |
EF-hand-dom_pair | SUPERFAMILY | EF-hand domain pair |
GO Term | Annotation Origin | Type |
---|---|---|
G2/M transition of mitotic cell cycle | Orthology | biological process |
signal transducer activity | Orthology | molecular function |
GTPase activator activity | Orthology | molecular function |
calcium ion binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
calmodulin binding | Orthology | molecular function |
intracellular | Orthology | cellular component |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
signal transduction | Orthology | biological process |
G-protein coupled receptor signaling pathway | Orthology | biological process |
brain development | Orthology | biological process |
membrane | Orthology | cellular component |
nuclear speck | Orthology | cellular component |
hydrolase activity | Orthology | molecular function |
enzyme binding | Orthology | molecular function |
nuclear membrane | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
intracellular signal transduction | Orthology | biological process |
protein homodimerization activity | Orthology | molecular function |
myelin sheath | Orthology | cellular component |
positive regulation of GTPase activity | Orthology | biological process |
negative regulation of transcription, DNA-templated | Orthology | biological process |
positive regulation of transcription, DNA-templated | Orthology | biological process |
metal ion binding | Orthology | molecular function |
extracellular exosome | Orthology | cellular component |
intracellular non-membrane-bounded organelle | Orthology | cellular component |
nuclear lumen | Orthology | cellular component |
anion binding | Orthology | molecular function |
organic substance metabolic process | Orthology | biological process |
phosphate-containing compound metabolic process | Orthology | biological process |
positive regulation of hydrolase activity | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
cell-cell signaling | Orthology | biological process |
nervous system process | Orthology | biological process |
regulation of signal transduction | Orthology | biological process |
multicellular organism development | Orthology | biological process |
cell adhesion molecule binding | Orthology | molecular function |
cell differentiation | Orthology | biological process |
anatomical structure development | Orthology | biological process |
cellular response to stress | Orthology | biological process |
positive regulation of signal transduction | Orthology | biological process |
protein phosphorylation | Orthology | biological process |
developmental process | Orthology | biological process |
sensory perception | Orthology | biological process |
cell cycle | Orthology | biological process |
cytokine-mediated signaling pathway | Orthology | biological process |
sexual reproduction | Orthology | biological process |
G1/S transition of mitotic cell cycle | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nuclear chromatin | Hs | cellular component | 447 | 6.93e-135 |
phosphatidylinositol phospholipase C activity | Hs | molecular function | 454 | 2.42e-137 |
phospholipase C activity | Hs | molecular function | 454 | 2.42e-137 |
signal transducer activity | Hs | molecular function | 454 | 2.42e-137 |
GTPase activator activity | Hs | molecular function | 447 | 6.93e-135 |
calcium ion binding | Hs | molecular function | 454 | 2.42e-137 |
protein binding | Hs | molecular function | 454 | 2.42e-137 |
calmodulin binding | Hs | molecular function | 454 | 2.42e-137 |
lamin binding | Hs | molecular function | 447 | 6.93e-135 |
phosphatidylinositol-4,5-bisphosphate binding | Hs | molecular function | 447 | 6.93e-135 |
intracellular | Hs | cellular component | 439 | 4.82e-132 |
nucleus | Hs | cellular component | 447 | 6.93e-135 |
nucleoplasm | Hs | cellular component | 454 | 2.42e-137 |
cytoplasm | Hs | cellular component | 447 | 6.93e-135 |
cytosol | Hs | cellular component | 454 | 2.42e-137 |
phosphoric diester hydrolase activity | Hs | molecular function | 454 | 2.42e-137 |
membrane | Hs | cellular component | 454 | 2.42e-137 |
nuclear speck | Hs | cellular component | 447 | 6.93e-135 |
hydrolase activity | Hs | molecular function | 454 | 2.42e-137 |
enzyme binding | Hs | molecular function | 447 | 6.93e-135 |
nuclear membrane | Hs | cellular component | 447 | 6.93e-135 |
macromolecular complex | Hs | cellular component | 454 | 2.42e-137 |
protein homodimerization activity | Hs | molecular function | 447 | 6.93e-135 |
myelin sheath | Hs | cellular component | 447 | 6.93e-135 |
cadherin binding | Hs | molecular function | 454 | 2.42e-137 |
metal ion binding | Hs | molecular function | 439 | 4.82e-132 |
extracellular exosome | Hs | cellular component | 447 | 6.93e-135 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
phosphatidylinositol phospholipase C activity | PIRSF | molecular function | 6.6E-179 |
calcium ion binding | PIRSF | molecular function | 6.6E-179 |
lipid metabolic process | SUPERFAMILY | biological process | 4.32E-124 |
signal transduction | SMART | biological process | 3.4E-62 |
phosphoric diester hydrolase activity | SUPERFAMILY | molecular function | 4.32E-124 |
lipid catabolic process | Pfam | biological process | 5.2E-6 |
intracellular signal transduction | PANTHER | biological process | 0.0 |