IPR Term	Analysis	Definition
Small_GTP-bd_dom	TIGRFAM	Small GTP-binding protein domain
Small_GTPase	Pfam	Small GTPase superfamily
P-loop_NTPase	SUPERFAMILY	P-loop containing nucleoside triphosphate hydrolase

GO Term	Annotation Origin	Type
Golgi membrane	Blast	cellular component
nucleotide binding	Orthology	molecular function
GTPase activity	Orthology	molecular function
protein binding	Orthology	molecular function
GTP binding	Orthology	molecular function
cytoplasm	Orthology	cellular component
lysosome	Orthology	cellular component
lysosomal membrane	Orthology	cellular component
endosome	Orthology	cellular component
endoplasmic reticulum	Blast	cellular component
endoplasmic reticulum membrane	Blast	cellular component
Golgi apparatus	Orthology	cellular component
cytosol	Orthology	cellular component
plasma membrane	Orthology	cellular component
protein transport	Orthology	biological process
membrane	Orthology	cellular component
cytoplasmic vesicle	Orthology	cellular component
melanosome	Orthology	cellular component
identical protein binding	Blast	molecular function
extracellular exosome	Orthology	cellular component
ubiquitin-like protein transferase activity	Orthology	molecular function
ligase activity	Orthology	molecular function
peptidase activity, acting on L-amino acid peptides	Orthology	molecular function
vacuolar membrane	Orthology	cellular component
intracellular non-membrane-bounded organelle	Orthology	cellular component
protein targeting	Orthology	biological process
establishment of protein localization to organelle	Orthology	biological process
organic substance metabolic process	Orthology	biological process
membrane organization	Orthology	biological process
organelle organization	Orthology	biological process
intracellular transport	Orthology	biological process
intracellular organelle part	Orthology	cellular component
whole membrane	Orthology	cellular component
bounding membrane of organelle	Orthology	cellular component
anion binding	Orthology	molecular function
guanyl ribonucleotide binding	Orthology	molecular function
purine ribonucleoside binding	Orthology	molecular function
immune system process	Orthology	biological process
cellular process	Orthology	biological process
endomembrane system	Orthology	cellular component
membrane part	Orthology	cellular component
macromolecular complex	Orthology	cellular component
cytoplasmic part	Orthology	cellular component
cell projection part	Orthology	cellular component
axon	Orthology	cellular component
synapse part	Orthology	cellular component
protein metabolic process	Orthology	biological process
enzyme binding	Orthology	molecular function
cell	Orthology	cellular component
macromolecular complex binding	Orthology	molecular function
organelle membrane	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
autophagosome assembly	Hs	biological process
nucleotide binding	Hs	molecular function
autophagosome membrane	Hs	cellular component
GTPase activity	Hs	molecular function
protein binding	Hs	molecular function
GTP binding	Hs	molecular function
cytoplasm	Hs	cellular component
lysosome	Hs	cellular component
lysosomal membrane	Hs	cellular component
endosome	Hs	cellular component
late endosome	Hs	cellular component
Golgi apparatus	Hs	cellular component
lipid droplet	Hs	cellular component
cytosol	Hs	cellular component
plasma membrane	Hs	cellular component
protein targeting to lysosome	Hs	biological process
lipid metabolic process	Hs	biological process
endocytosis	Hs	biological process
autophagy	Hs	biological process
endosome to lysosome transport	Hs	biological process
endosome membrane	Hs	cellular component
protein transport	Hs	biological process
membrane	Hs	cellular component
lipid catabolic process	Hs	biological process
GDP binding	Hs	molecular function
antigen processing and presentation of exogenous peptide antigen via MHC class II	Hs	biological process
protein to membrane docking	Hs	biological process
secretory granule membrane	Hs	cellular component
phagocytic vesicle membrane	Hs	cellular component
retromer complex	Hs	cellular component
cytoplasmic vesicle	Hs	cellular component
late endosome membrane	Hs	cellular component
extrinsic component of lysosome membrane	Hs	cellular component
melanosome membrane	Hs	cellular component
pre-autophagosomal structure membrane	Hs	cellular component
retrograde transport, endosome to Golgi	Hs	biological process
terminal bouton	Hs	cellular component
early endosome to late endosome transport	Hs	biological process
phagocytic vesicle	Hs	cellular component
bone resorption	Hs	biological process
positive regulation of protein catabolic process	Hs	biological process
Rac GTPase binding	Hs	molecular function
extracellular exosome	Hs	cellular component
phagosome maturation	Hs	biological process
phagosome acidification	Hs	biological process
phagosome-lysosome fusion	Hs	biological process
alveolar lamellar body	Hs	cellular component
retromer complex binding	Hs	molecular function

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
Golgi membrane	Hs	cellular component	179	1.27e-57
nucleotide binding	Hs	molecular function	317	8.90e-112
autophagosome membrane	Hs	cellular component	317	8.90e-112
GTPase activity	Hs	molecular function	317	8.90e-112
protein binding	Hs	molecular function	317	8.90e-112
GTP binding	Hs	molecular function	317	8.90e-112
cytoplasm	Hs	cellular component	317	8.90e-112
lysosome	Hs	cellular component	317	8.90e-112
lysosomal membrane	Hs	cellular component	317	8.90e-112
endosome	Hs	cellular component	317	8.90e-112
late endosome	Hs	cellular component	317	8.90e-112
endoplasmic reticulum	Hs	cellular component	179	1.27e-57
endoplasmic reticulum membrane	Hs	cellular component	179	1.27e-57
Golgi apparatus	Hs	cellular component	317	8.90e-112
lipid droplet	Hs	cellular component	317	8.90e-112
cytosol	Hs	cellular component	317	8.90e-112
plasma membrane	Hs	cellular component	317	8.90e-112
endosome membrane	Hs	cellular component	317	8.90e-112
membrane	Hs	cellular component	317	8.90e-112
GDP binding	Hs	molecular function	317	8.90e-112
transport vesicle	Hs	cellular component	179	1.27e-57
cytoplasmic vesicle membrane	Hs	cellular component	179	1.27e-57
secretory granule membrane	Hs	cellular component	317	8.90e-112
phagocytic vesicle membrane	Hs	cellular component	317	8.90e-112
retromer complex	Hs	cellular component	317	8.90e-112
cytoplasmic vesicle	Hs	cellular component	317	8.90e-112
late endosome membrane	Hs	cellular component	317	8.90e-112
extrinsic component of lysosome membrane	Hs	cellular component	317	8.90e-112
trans-Golgi network membrane	Hs	cellular component	179	1.27e-57
melanosome membrane	Hs	cellular component	317	8.90e-112
pre-autophagosomal structure membrane	Hs	cellular component	317	8.90e-112
melanosome	Hs	cellular component	179	1.27e-57
identical protein binding	Hs	molecular function	179	1.27e-57
terminal bouton	Hs	cellular component	317	8.90e-112
phagocytic vesicle	Hs	cellular component	317	8.90e-112
Rac GTPase binding	Hs	molecular function	317	8.90e-112
extracellular exosome	Hs	cellular component	317	8.90e-112
alveolar lamellar body	Hs	cellular component	317	8.90e-112
retromer complex binding	Hs	molecular function	317	8.90e-112

GO Term	Analysis	Type	e-value
GTPase activity	Pfam	molecular function	1.7E-48
GTP binding	Pfam	molecular function	1.7E-48