Gene Card
Best human hits
CDK7; GSK3A; GSK3B
Species
Unique Gene ID
Phmamm.g00014358
Gene Model ID
Phmamm.CG.MTP2014.S1281.g14358
Location
S1281:21861..40443
Transcript Models and Sequences
AHC0AAA11YE16
Plate: Plate_11_E16
AHC0AAA17YB13
Plate: Plate_17_B13
AHC0AAA2YC02
Plate: Plate_2_C02
AHC0AAA4YG16
Plate: Plate_4_G16
AHC0AAA6YO24
Plate: Plate_6_O24
AHC0AAA7YB23
Plate: Plate_7_B23
AHC0AAA7YI05
Plate: Plate_7_I05
AHC0AAA8YG10
Plate: Plate_8_G10
AHC0AAA9YF20
Plate: Plate_9_F20
AHC0AAA29YH22
Plate: Plate_29_H22
AHC0AAA32YJ19
Plate: Plate_32_J19
AHC0AAA32YP11
Plate: Plate_32_P11
AHC0AAA40YB15
Plate: Plate_40_B15
AHC0AAA42YA15
Plate: Plate_42_A15
AHC0AAA55YB10
Plate: Plate_55_B10
AHC0AAA68YN06
Plate: Plate_68_N06
AHC0AAA75YO06
Plate: Plate_75_O06
AHC0AAA100YD21
Plate: Plate_100_D21
AHC0AAA106YA10
Plate: Plate_106_A10
AHC0AAA106YA15
Plate: Plate_106_A15
AHC0AAA111YL24
Plate: Plate_111_L24
AHC0AAA111YM20
Plate: Plate_111_M20
AHC0AAA113YD18
Plate: Plate_113_D18
AHC0AAA116YG15
Plate: Plate_116_G15
AHC0AAA118YH14
Plate: Plate_118_H14
AHC0AAA126YA01
Plate: Plate_126_A01
AHC0AAA126YK10
Plate: Plate_126_K10
AHC0AAA127YE12
Plate: Plate_127_E12
AHC0AAA129YD09
Plate: Plate_129_D09
AHC0AAA132YC01
Plate: Plate_132_C01
AHC0AAA138YB14
Plate: Plate_138_B14
AHC0AAA143YF22
Plate: Plate_143_F22
AHC0AAA145YM12
Plate: Plate_145_M12
AHC0AAA152YN07
Plate: Plate_152_N07
AHC0AAA86YM09
Plate: Plate_86_M09
AHC0AAA87YM08
Plate: Plate_87_M08
AHC0AAA90YL03
Plate: Plate_90_L03
AHC0AAA92YP16
Plate: Plate_92_P16
AHC0AAA106YC12
Plate: Plate_106_C12
AHC0AAA166YG15
Plate: Plate_166_G15
AHC0AAA169YJ20
Plate: Plate_169_J20
AHC0AAA174YA16
Plate: Plate_174_A16
AHC0AAA188YB22
Plate: Plate_188_B22
AHC0AAA201YC08
Plate: Plate_201_C08
AHC0AAA210YG04
Plate: Plate_210_G04
AHC0AAA211YN17
Plate: Plate_211_N17
AHC0AAA216YK10
Plate: Plate_216_K10
AHC0AAA220YJ09
Plate: Plate_220_J09
AHC0AAA224YI23
Plate: Plate_224_I23
AHC0AAA230YP02
Plate: Plate_230_P02
AHC0AAA237YM01
Plate: Plate_237_M01
AHC0AAA246YF15
Plate: Plate_246_F15
AHC0AAA246YP18
Plate: Plate_246_P18
AHC0AAA253YB09
Plate: Plate_253_B09
AHC0AAA261YI23
Plate: Plate_261_I23
AHC0AAA55YD12
Plate: Plate_55_D12
AHC0AAA92YP14
Plate: Plate_92_P14
n/a
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IPR Term | Analysis | Definition |
---|---|---|
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
Prot_kinase_dom | SMART | Protein kinase domain |
Prot_kinase_dom | Pfam | Protein kinase domain |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
transcription coactivator activity | Blast | molecular function |
protein kinase activity | Orthology | molecular function |
protein serine/threonine kinase activity | Orthology | molecular function |
receptor binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
nucleus | Blast | cellular component |
nucleoplasm | Blast | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrion | Orthology | cellular component |
centrosome | Blast | cellular component |
cytosol | Orthology | cellular component |
microtubule | Orthology | cellular component |
plasma membrane | Blast | cellular component |
protein phosphorylation | Orthology | biological process |
cell cycle | Blast | biological process |
nervous system development | Orthology | biological process |
protein C-terminus binding | Blast | molecular function |
negative regulation of signal transduction | Orthology | biological process |
positive regulation of gene expression | Orthology | biological process |
membrane | Blast | cellular component |
kinase activity | Orthology | molecular function |
phosphorylation | Orthology | biological process |
cell migration | Orthology | biological process |
transferase activity | Orthology | molecular function |
protein kinase binding | Orthology | molecular function |
ubiquitin protein ligase binding | Blast | molecular function |
intracellular signal transduction | Orthology | biological process |
neuronal cell body | Orthology | cellular component |
positive regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
perinuclear region of cytoplasm | Blast | cellular component |
negative regulation of canonical Wnt signaling pathway | Orthology | biological process |
postsynapse | Orthology | cellular component |
organic substance metabolic process | Orthology | biological process |
oxidation-reduction process | Orthology | biological process |
nucleobase-containing compound metabolic process | Orthology | biological process |
regulation of gene expression | Orthology | biological process |
G-protein coupled receptor signaling pathway | Orthology | biological process |
developmental process | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
cell-cell signaling | Orthology | biological process |
cytoplasmic part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
protein ubiquitination | Orthology | biological process |
proteolysis | Orthology | biological process |
positive regulation of apoptotic process | Orthology | biological process |
DNA metabolic process | Orthology | biological process |
protein metabolic process | Orthology | biological process |
chemical synaptic transmission | Orthology | biological process |
nervous system process | Orthology | biological process |
apoptotic process | Orthology | biological process |
organelle organization | Orthology | biological process |
regulation of cellular metabolic process | Orthology | biological process |
transcription factor binding | Blast | molecular function |
enzyme binding | Blast | molecular function |
molecular transducer activity | Blast | molecular function |
nucleoplasm part | Blast | cellular component |
nucleoside-triphosphatase activity | Blast | molecular function |
nuclear part | Blast | cellular component |
cytoskeletal protein binding | Blast | molecular function |
plasma membrane part | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 479 | 1.17e-170 |
RNA polymerase II transcription factor binding | Hs | molecular function | 479 | 1.17e-170 |
protease binding | Hs | molecular function | 479 | 1.17e-170 |
p53 binding | Hs | molecular function | 479 | 1.17e-170 |
transcription coactivator activity | Hs | molecular function | 147 | 8.38e-42 |
protein kinase activity | Hs | molecular function | 479 | 1.17e-170 |
protein serine/threonine kinase activity | Hs | molecular function | 479 | 1.17e-170 |
cyclin-dependent protein serine/threonine kinase activity | Hs | molecular function | 147 | 8.38e-42 |
receptor binding | Hs | molecular function | 477 | 4.57e-169 |
protein binding | Hs | molecular function | 479 | 1.17e-170 |
ATP binding | Hs | molecular function | 479 | 1.17e-170 |
nucleus | Hs | cellular component | 479 | 1.17e-170 |
nucleoplasm | Hs | cellular component | 479 | 1.17e-170 |
holo TFIIH complex | Hs | cellular component | 147 | 8.38e-42 |
cytoplasm | Hs | cellular component | 479 | 1.17e-170 |
mitochondrion | Hs | cellular component | 479 | 1.17e-170 |
centrosome | Hs | cellular component | 479 | 1.17e-170 |
cytosol | Hs | cellular component | 479 | 1.17e-170 |
microtubule | Hs | cellular component | 477 | 4.57e-169 |
plasma membrane | Hs | cellular component | 479 | 1.17e-170 |
beta-catenin binding | Hs | molecular function | 479 | 1.17e-170 |
protein C-terminus binding | Hs | molecular function | 147 | 8.38e-42 |
DNA-dependent ATPase activity | Hs | molecular function | 147 | 8.38e-42 |
RNA polymerase II carboxy-terminal domain kinase activity | Hs | molecular function | 147 | 8.38e-42 |
membrane | Hs | cellular component | 479 | 1.17e-170 |
kinase activity | Hs | molecular function | 479 | 1.17e-170 |
transferase activity | Hs | molecular function | 479 | 1.17e-170 |
protein kinase binding | Hs | molecular function | 479 | 1.17e-170 |
cyclin-dependent protein kinase activating kinase holoenzyme complex | Hs | cellular component | 147 | 8.38e-42 |
beta-catenin destruction complex | Hs | cellular component | 479 | 1.17e-170 |
ubiquitin protein ligase binding | Hs | molecular function | 479 | 1.17e-170 |
protein kinase A catalytic subunit binding | Hs | molecular function | 479 | 1.17e-170 |
dynactin binding | Hs | molecular function | 479 | 1.17e-170 |
neuronal cell body | Hs | cellular component | 477 | 4.57e-169 |
perinuclear region of cytoplasm | Hs | cellular component | 147 | 8.38e-42 |
tau-protein kinase activity | Hs | molecular function | 479 | 1.17e-170 |
androgen receptor binding | Hs | molecular function | 147 | 8.38e-42 |
NF-kappaB binding | Hs | molecular function | 479 | 1.17e-170 |
TFIIK complex | Hs | cellular component | 147 | 8.38e-42 |
apical dendrite | Hs | cellular component | 477 | 4.57e-169 |
postsynapse | Hs | cellular component | 479 | 1.17e-170 |
proximal dendrite | Hs | cellular component | 477 | 4.57e-169 |
Wnt signalosome | Hs | cellular component | 479 | 1.17e-170 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 7.1E-49 |
ATP binding | Pfam | molecular function | 7.1E-49 |
protein phosphorylation | Pfam | biological process | 7.1E-49 |