IPR Term	Analysis	Definition
PH_domain	Pfam	Pleckstrin homology domain
Ankyrin_rpt-contain_dom	ProSiteProfiles	Ankyrin repeat-containing domain
Small_GTPase	Pfam	Small GTPase superfamily
ARFGAP/RecO	SUPERFAMILY	ARFGAP/RecO-like zinc finger
Ankyrin_rpt-contain_dom	CDD	Ankyrin repeat-containing domain
PH_domain	ProSiteProfiles	Pleckstrin homology domain
Ankyrin_rpt-contain_sf	Gene3D	Ankyrin repeat-containing domain superfamily
P-loop_NTPase	SUPERFAMILY	P-loop containing nucleoside triphosphate hydrolase
Ankyrin_rpt-contain_sf	SUPERFAMILY	Ankyrin repeat-containing domain superfamily
PH-like_dom_sf	Gene3D	PH-like domain superfamily
Ankyrin_rpt-contain_dom	Pfam	Ankyrin repeat-containing domain
Small_GTPase_Ras	ProSiteProfiles	Small GTPase superfamily, Ras type
ArfGAP_dom	Pfam	Arf GTPase activating protein
ArfGAP_dom_sf	Gene3D	ArfGAP domain superfamily
PH_domain	SMART	Pleckstrin homology domain

GO Term	Annotation Origin	Type
nucleotide binding	Orthology	molecular function
GTPase activity	Orthology	molecular function
GTPase activator activity	Orthology	molecular function
protein binding	Orthology	molecular function
GTP binding	Orthology	molecular function
nucleus	Orthology	cellular component
nucleolus	Orthology	cellular component
cytoplasm	Orthology	cellular component
mitochondrion	Orthology	cellular component
signal transduction	Orthology	biological process
protein transport	Orthology	biological process
membrane	Orthology	cellular component
protein kinase binding	Orthology	molecular function
negative regulation of apoptotic process	Orthology	biological process
positive regulation of GTPase activity	Orthology	biological process
positive regulation of transcription from RNA polymerase II promoter	Orthology	biological process
metal ion binding	Orthology	molecular function
extracellular exosome	Orthology	cellular component
anion binding	Orthology	molecular function
intracellular signal transduction	Orthology	biological process
positive regulation of signal transduction	Orthology	biological process
enzyme activator activity	Orthology	molecular function
protein kinase activity	Orthology	molecular function
positive regulation of catalytic activity	Orthology	biological process
protein metabolic process	Orthology	biological process
cell surface receptor signaling pathway	Orthology	biological process
negative regulation of signal transduction	Orthology	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
nucleotide binding	Hs	molecular function
GTPase activity	Hs	molecular function
GTPase activator activity	Hs	molecular function
protein binding	Hs	molecular function
GTP binding	Hs	molecular function
phospholipid binding	Hs	molecular function
nucleus	Hs	cellular component
nucleolus	Hs	cellular component
cytoplasm	Hs	cellular component
mitochondrion	Hs	cellular component
signal transduction	Hs	biological process
positive regulation of phosphatidylinositol 3-kinase signaling	Hs	biological process
protein transport	Hs	biological process
membrane	Hs	cellular component
protein kinase binding	Hs	molecular function
protein kinase activator activity	Hs	molecular function
activation of protein kinase activity	Hs	biological process
negative regulation of protein catabolic process	Hs	biological process
negative regulation of apoptotic process	Hs	biological process
negative regulation of neuron apoptotic process	Hs	biological process
positive regulation of GTPase activity	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
positive regulation of JAK-STAT cascade	Hs	biological process
metal ion binding	Hs	molecular function
extracellular exosome	Hs	cellular component
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nucleotide binding	Hs	molecular function	479	5.86e-159
GTPase activity	Hs	molecular function	479	5.86e-159
GTPase activator activity	Hs	molecular function	479	5.86e-159
protein binding	Hs	molecular function	479	5.86e-159
GTP binding	Hs	molecular function	479	5.86e-159
phospholipid binding	Hs	molecular function	402	1.65e-127
nucleus	Hs	cellular component	294	5.41e-87
nucleolus	Hs	cellular component	294	5.41e-87
cytoplasm	Hs	cellular component	479	5.86e-159
mitochondrion	Hs	cellular component	294	5.41e-87
membrane	Hs	cellular component	479	5.86e-159
protein kinase binding	Hs	molecular function	294	5.41e-87
protein kinase activator activity	Hs	molecular function	294	5.41e-87
metal ion binding	Hs	molecular function	479	5.86e-159
extracellular exosome	Hs	cellular component	294	5.41e-87

GO Term	Analysis	Type	e-value
GTPase activity	Pfam	molecular function	1.4E-18
GTPase activator activity	Pfam	molecular function	1.0E-6
GTP binding	Pfam	molecular function	1.4E-18
signal transduction	ProSiteProfiles	biological process	12.455
membrane	ProSiteProfiles	cellular component	12.455