Gene Card
Best human hits
HERC2; MIB1; MIB2
Species
Unique Gene ID
Phmamm.g00003512
Gene Model ID
Phmamm.CG.MTP2014.S115.g03512
Location
S115:156668..161299
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Mib_Herc2_sf | SUPERFAMILY | Mib/herc2 domain superfamily |
Mib_Herc2 | Pfam | Mib-herc2 |
Mib_Herc2_sf | Gene3D | Mib/herc2 domain superfamily |
Mib_Herc2 | ProSiteProfiles | Mib-herc2 |
Znf_ZZ | ProSiteProfiles | Zinc finger, ZZ-type |
Znf_ZZ | Pfam | Zinc finger, ZZ-type |
GO Term | Annotation Origin | Type |
---|---|---|
protein polyubiquitination | Orthology | biological process |
actin binding | Orthology | molecular function |
ubiquitin-protein transferase activity | Orthology | molecular function |
signal transducer activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Blast | cellular component |
nucleoplasm | Blast | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrial inner membrane | Blast | cellular component |
endosome | Orthology | cellular component |
early endosome | Orthology | cellular component |
centrosome | Blast | cellular component |
microtubule organizing center | Blast | cellular component |
cytosol | Orthology | cellular component |
cytoskeleton | Blast | cellular component |
plasma membrane | Blast | cellular component |
Notch signaling pathway | Orthology | biological process |
zinc ion binding | Orthology | molecular function |
membrane | Blast | cellular component |
protein ubiquitination | Orthology | biological process |
transferase activity | Orthology | molecular function |
cytoplasmic vesicle | Blast | cellular component |
ubiquitin protein ligase binding | Blast | molecular function |
metal ion binding | Orthology | molecular function |
intracellular part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
transcription factor activity, sequence-specific DNA binding | Orthology | molecular function |
intracellular signal transduction | Orthology | biological process |
positive regulation of signal transduction | Orthology | biological process |
enzyme binding | Blast | molecular function |
molecular function regulator | Blast | molecular function |
cytoplasmic part | Blast | cellular component |
organelle | Blast | cellular component |
postsynapse | Blast | cellular component |
neuron part | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
ubiquitin ligase complex | Hs | cellular component |
protein polyubiquitination | Hs | biological process |
actin binding | Hs | molecular function |
ubiquitin-protein transferase activity | Hs | molecular function |
signal transducer activity | Hs | molecular function |
protein binding | Hs | molecular function |
cytoplasm | Hs | cellular component |
endosome | Hs | cellular component |
early endosome | Hs | cellular component |
cytosol | Hs | cellular component |
Notch signaling pathway | Hs | biological process |
zinc ion binding | Hs | molecular function |
protein ubiquitination | Hs | biological process |
transferase activity | Hs | molecular function |
positive regulation of I-kappaB kinase/NF-kappaB signaling | Hs | biological process |
metal ion binding | Hs | molecular function |
ubiquitin protein ligase activity | Hs | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
ubiquitin ligase complex | Hs | cellular component | 182 | 5.29e-51 |
actin binding | Hs | molecular function | 182 | 5.29e-51 |
ubiquitin-protein transferase activity | Hs | molecular function | 197 | 2.61e-56 |
signal transducer activity | Hs | molecular function | 182 | 5.29e-51 |
guanyl-nucleotide exchange factor activity | Hs | molecular function | 63.2 | 1.01e-10 |
protein binding | Hs | molecular function | 197 | 2.61e-56 |
nucleus | Hs | cellular component | 63.2 | 1.01e-10 |
nucleoplasm | Hs | cellular component | 63.2 | 1.01e-10 |
cytoplasm | Hs | cellular component | 197 | 2.61e-56 |
mitochondrial inner membrane | Hs | cellular component | 63.2 | 1.01e-10 |
endosome | Hs | cellular component | 182 | 5.29e-51 |
early endosome | Hs | cellular component | 182 | 5.29e-51 |
centrosome | Hs | cellular component | 197 | 2.61e-56 |
centriole | Hs | cellular component | 63.2 | 1.01e-10 |
microtubule organizing center | Hs | cellular component | 197 | 2.61e-56 |
cytosol | Hs | cellular component | 197 | 2.61e-56 |
cytoskeleton | Hs | cellular component | 197 | 2.61e-56 |
plasma membrane | Hs | cellular component | 197 | 2.61e-56 |
zinc ion binding | Hs | molecular function | 197 | 2.61e-56 |
postsynaptic density | Hs | cellular component | 197 | 2.61e-56 |
membrane | Hs | cellular component | 197 | 2.61e-56 |
transferase activity | Hs | molecular function | 197 | 2.61e-56 |
cytoplasmic vesicle | Hs | cellular component | 197 | 2.61e-56 |
ubiquitin protein ligase binding | Hs | molecular function | 63.2 | 1.01e-10 |
SUMO binding | Hs | molecular function | 63.2 | 1.01e-10 |
metal ion binding | Hs | molecular function | 197 | 2.61e-56 |
ubiquitin protein ligase activity | Hs | molecular function | 182 | 5.29e-51 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
ubiquitin-protein transferase activity | Gene3D | molecular function | 6.4E-23 |
zinc ion binding | Pfam | molecular function | 9.7E-6 |
protein ubiquitination | Pfam | biological process | 8.9E-22 |
metal ion binding | Gene3D | molecular function | 6.4E-23 |