IPR Term	Analysis	Definition
AhpC/TSA	Pfam	Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Thioredoxin_domain	ProSiteProfiles	Thioredoxin domain
Peroxiredoxin_C	Pfam	Peroxiredoxin, C-terminal
Peroxiredoxin_AhpC-typ	PIRSF	Peroxiredoxin, AhpC-type
Thioredoxin-like_sf	SUPERFAMILY	Thioredoxin-like superfamily

GO Term	Annotation Origin	Type
RNA binding	Orthology	molecular function
protein binding	Orthology	molecular function
extracellular region	Blast	cellular component
extracellular space	Orthology	cellular component
cell	Orthology	cellular component
nucleus	Orthology	cellular component
cytoplasm	Orthology	cellular component
mitochondrion	Orthology	cellular component
endoplasmic reticulum	Blast	cellular component
cytosol	Orthology	cellular component
response to oxidative stress	Orthology	biological process
cell proliferation	Orthology	biological process
melanosome	Orthology	cellular component
identical protein binding	Orthology	molecular function
protein homodimerization activity	Blast	molecular function
regulation of apoptotic process	Orthology	biological process
negative regulation of apoptotic process	Orthology	biological process
myelin sheath	Orthology	cellular component
oxidation-reduction process	Orthology	biological process
extracellular exosome	Orthology	cellular component
system development	Orthology	biological process
catalytic activity	Orthology	molecular function
cellular response to stress	Orthology	biological process
cellular metabolic process	Orthology	biological process
immune system process	Orthology	biological process
cell adhesion molecule binding	Orthology	molecular function
intracellular organelle part	Blast	cellular component
cytoplasmic vesicle	Blast	cellular component
endomembrane system	Blast	cellular component
intracellular organelle lumen	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
response to reactive oxygen species	Hs	biological process
skeletal system development	Hs	biological process
retina homeostasis	Hs	biological process
RNA binding	Hs	molecular function
peroxidase activity	Hs	molecular function
protein binding	Hs	molecular function
extracellular space	Hs	cellular component
cell	Hs	cellular component
nucleus	Hs	cellular component
cytoplasm	Hs	cellular component
mitochondrion	Hs	cellular component
cytosol	Hs	cellular component
response to oxidative stress	Hs	biological process
cell proliferation	Hs	biological process
thioredoxin peroxidase activity	Hs	molecular function
antioxidant activity	Hs	molecular function
oxidoreductase activity	Hs	molecular function
removal of superoxide radicals	Hs	biological process
erythrocyte homeostasis	Hs	biological process
cellular response to oxidative stress	Hs	biological process
melanosome	Hs	cellular component
hydrogen peroxide catabolic process	Hs	biological process
identical protein binding	Hs	molecular function
regulation of apoptotic process	Hs	biological process
negative regulation of apoptotic process	Hs	biological process
myelin sheath	Hs	cellular component
cadherin binding	Hs	molecular function
cell redox homeostasis	Hs	biological process
peroxiredoxin activity	Hs	molecular function
oxidation-reduction process	Hs	biological process
extracellular exosome	Hs	cellular component
cellular oxidant detoxification	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
RNA binding	Hs	molecular function	301	3.90e-105
peroxidase activity	Hs	molecular function	308	1.18e-107
protein binding	Hs	molecular function	308	1.18e-107
extracellular region	Hs	cellular component	276	5.22e-94
extracellular space	Hs	cellular component	301	3.90e-105
cell	Hs	cellular component	308	1.18e-107
nucleus	Hs	cellular component	301	3.90e-105
cytoplasm	Hs	cellular component	308	1.18e-107
mitochondrion	Hs	cellular component	301	3.90e-105
endoplasmic reticulum	Hs	cellular component	276	5.22e-94
smooth endoplasmic reticulum	Hs	cellular component	276	5.22e-94
cytosol	Hs	cellular component	308	1.18e-107
thioredoxin peroxidase activity	Hs	molecular function	308	1.18e-107
antioxidant activity	Hs	molecular function	308	1.18e-107
oxidoreductase activity	Hs	molecular function	308	1.18e-107
secretory granule lumen	Hs	cellular component	276	5.22e-94
melanosome	Hs	cellular component	301	3.90e-105
identical protein binding	Hs	molecular function	301	3.90e-105
protein homodimerization activity	Hs	molecular function	276	5.22e-94
myelin sheath	Hs	cellular component	301	3.90e-105
cadherin binding	Hs	molecular function	301	3.90e-105
peroxiredoxin activity	Hs	molecular function	308	1.18e-107
extracellular exosome	Hs	cellular component	308	1.18e-107
ficolin-1-rich granule lumen	Hs	cellular component	276	5.22e-94

GO Term	Analysis	Type	e-value
antioxidant activity	Pfam	molecular function	2.8E-36
oxidoreductase activity	Pfam	molecular function	2.8E-36
cell redox homeostasis	ProSiteProfiles	biological process	16.619
peroxiredoxin activity	Pfam	molecular function	3.5E-12
oxidation-reduction process	Pfam	biological process	2.8E-36