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GENE CARD

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Gene Card

Best human hits

KLHL18; KLHL3; KLHL5

Species

P.mammillata

Unique Gene ID

Phmamm.g00013432

Gene Model ID

Phmamm.CG.MTP2014.S1048.g13432

Location

S1048:21997..31103

Transcript Models and Sequences

  Phmamm.CG.MTP2014.S1048.g13432.01.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

11 results

IPR Term Analysis Definition
Znf_C2H2_type SMART Zinc finger C2H2-type
Znf_C2H2_type ProSitePatterns Zinc finger C2H2-type
Znf_C2H2_type ProSiteProfiles Zinc finger C2H2-type
SKP1/BTB/POZ_sf SUPERFAMILY SKP1/BTB/POZ domain superfamily
BACK Pfam BTB/Kelch-associated
Kelch-typ_b-propeller SUPERFAMILY Kelch-type beta propeller
Znf_C2H2_sf SUPERFAMILY Zinc finger C2H2 superfamily
Kelch_1 Pfam Kelch repeat type 1
Kelch_1 SMART Kelch repeat type 1
BACK SMART BTB/Kelch-associated
Kelch-typ_b-propeller Gene3D Kelch-type beta propeller

GOSlim

51 results

GO Term Annotation Origin Type
actin binding Blast molecular function
ubiquitin-protein transferase activity Blast molecular function
structural molecule activity Blast molecular function
protein binding Orthology molecular function
cytoplasm Orthology cellular component
cytosol Blast cellular component
cytoskeleton Blast cellular component
nucleic acid binding Orthology molecular function
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
RNA polymerase II regulatory region sequence-specific DNA binding Orthology molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding Orthology molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Orthology molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Orthology molecular function
DNA binding Orthology molecular function
transcription factor activity, sequence-specific DNA binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
transcription from RNA polymerase II promoter Orthology biological process
signal transduction Orthology biological process
heart development Orthology biological process
transcription factor binding Orthology molecular function
neurogenesis Orthology biological process
positive regulation of Wnt signaling pathway Orthology biological process
intracellular membrane-bounded organelle Orthology cellular component
sequence-specific DNA binding Orthology molecular function
transcription regulatory region DNA binding Orthology molecular function
negative regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
metal ion binding Orthology molecular function
intracellular organelle part Orthology cellular component
intracellular non-membrane-bounded organelle Orthology cellular component
animal organ development Orthology biological process
anatomical structure morphogenesis Orthology biological process
anatomical structure formation involved in morphogenesis Orthology biological process
nervous system development Orthology biological process
organelle organization Orthology biological process
hydrolase activity Orthology molecular function
cellular protein modification process Orthology biological process
reproductive process Orthology biological process
anatomical structure development Orthology biological process
nucleoplasm part Orthology cellular component
macromolecular complex Orthology cellular component
developmental process Orthology biological process
brain development Orthology biological process
multicellular organism development Orthology biological process
cell surface receptor signaling pathway Orthology biological process
negative regulation of signal transduction Orthology biological process
intracellular part Blast cellular component

GO (Orthology)

51 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
protein binding Hs molecular function
cytoplasm Hs cellular component
nucleic acid binding Hs molecular function
negative regulation of transcription from RNA polymerase II promoter Hs biological process
heterochromatin Hs cellular component
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function
eye development Hs biological process
ureteric bud development Hs biological process
branching involved in ureteric bud morphogenesis Hs biological process
kidney development Hs biological process
neural tube closure Hs biological process
DNA binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
histone deacetylase activity Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
transcription from RNA polymerase II promoter Hs biological process
signal transduction Hs biological process
heart development Hs biological process
beta-catenin binding Hs molecular function
transcription factor binding Hs molecular function
gonad development Hs biological process
tissue development Hs biological process
chromocenter Hs cellular component
histone deacetylation Hs biological process
NuRD complex Hs cellular component
stem cell population maintenance Hs biological process
olfactory nerve development Hs biological process
neural tube development Hs biological process
pituitary gland development Hs biological process
neurogenesis Hs biological process
positive regulation of Wnt signaling pathway Hs biological process
adrenal gland development Hs biological process
embryonic limb morphogenesis Hs biological process
somatic stem cell population maintenance Hs biological process
intracellular membrane-bounded organelle Hs cellular component
sequence-specific DNA binding Hs molecular function
transcription regulatory region DNA binding Hs molecular function
negative regulation of smoothened signaling pathway Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
metal ion binding Hs molecular function
embryonic digestive tract development Hs biological process
limb development Hs biological process

GO (Blast)

8 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
actin binding Hs molecular function 102 1.29e-22
ubiquitin-protein transferase activity Hs molecular function 102 1.29e-22
structural molecule activity Hs molecular function 102 1.29e-22
protein binding Hs molecular function 102 1.29e-22
cytoplasm Hs cellular component 102 1.29e-22
cytosol Hs cellular component 102 1.29e-22
cytoskeleton Hs cellular component 102 1.29e-22
Cul3-RING ubiquitin ligase complex Hs cellular component 102 1.29e-22

GO (InterProScan)

2 results

GO Term Analysis Type e-value
protein binding SUPERFAMILY molecular function 3.4E-38
nucleic acid binding SMART molecular function 0.007