IPR Term	Analysis	Definition
SDR_fam	Pfam	Short-chain dehydrogenase/reductase SDR
NAD(P)-bd_dom_sf	SUPERFAMILY	NAD(P)-binding domain superfamily
SDR_fam	PRINTS	Short-chain dehydrogenase/reductase SDR

GO Term	Annotation Origin	Type
protein binding	Orthology	molecular function
extracellular space	Orthology	cellular component
nucleoplasm	Orthology	cellular component
cytoplasm	Orthology	cellular component
endoplasmic reticulum	Blast	cellular component
endoplasmic reticulum membrane	Blast	cellular component
cytosol	Orthology	cellular component
membrane	Blast	cellular component
integral component of membrane	Blast	cellular component
oxidation-reduction process	Orthology	biological process
extracellular exosome	Orthology	cellular component
extracellular vesicle	Orthology	cellular component
catalytic activity	Orthology	molecular function
cellular metabolic process	Orthology	biological process
cellular biosynthetic process	Orthology	biological process
anatomical structure development	Orthology	biological process
cell differentiation	Orthology	biological process
metabolic process	Orthology	biological process
nervous system process	Orthology	biological process
anion binding	Orthology	molecular function
nucleotide binding	Orthology	molecular function
coenzyme binding	Orthology	molecular function

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
3-keto sterol reductase activity	Hs	molecular function
carbonyl reductase (NADPH) activity	Hs	molecular function
protein binding	Hs	molecular function
extracellular space	Hs	cellular component
nucleoplasm	Hs	cellular component
cytoplasm	Hs	cellular component
cytosol	Hs	cellular component
xenobiotic metabolic process	Hs	biological process
oxidoreductase activity	Hs	molecular function
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	Hs	molecular function
cyclooxygenase pathway	Hs	biological process
epithelial cell differentiation	Hs	biological process
vitamin K metabolic process	Hs	biological process
15-hydroxyprostaglandin dehydrogenase (NADP+) activity	Hs	molecular function
prostaglandin-E2 9-reductase activity	Hs	molecular function
cognition	Hs	biological process
oxidation-reduction process	Hs	biological process
extracellular exosome	Hs	cellular component
NADPH binding	Hs	molecular function
extracellular vesicle	Hs	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
3-keto sterol reductase activity	Hs	molecular function	311	4.75e-107
carbonyl reductase (NADPH) activity	Hs	molecular function	365	2.98e-128
protein binding	Hs	molecular function	365	2.98e-128
extracellular space	Hs	cellular component	311	4.75e-107
nucleoplasm	Hs	cellular component	311	4.75e-107
cytoplasm	Hs	cellular component	365	2.98e-128
endoplasmic reticulum	Hs	cellular component	61.6	7.53e-11
endoplasmic reticulum membrane	Hs	cellular component	61.6	7.53e-11
cytosol	Hs	cellular component	365	2.98e-128
membrane	Hs	cellular component	61.6	7.53e-11
integral component of membrane	Hs	cellular component	61.6	7.53e-11
oxidoreductase activity	Hs	molecular function	365	2.98e-128
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	Hs	molecular function	365	2.98e-128
15-hydroxyprostaglandin dehydrogenase (NADP+) activity	Hs	molecular function	365	2.98e-128
prostaglandin-E2 9-reductase activity	Hs	molecular function	365	2.98e-128
extracellular exosome	Hs	cellular component	365	2.98e-128
NADPH binding	Hs	molecular function	311	4.75e-107
extracellular vesicle	Hs	cellular component	365	2.98e-128