Gene Card
Best human hits
GCLC
Species
Unique Gene ID
Phfumi.g00002158
Gene Model ID
Phfumi.CG.MTP2014.S484.g02158
Location
S484:12362..15099
Transcript Models and Sequences
Phfumi.CG.MTP2014.S484.g02158.01.t
Phfumi.CG.MTP2014.S484.g02158.02.t
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
GCS | Pfam | Glutamate-cysteine ligase catalytic subunit |
Gln_synth/guanido_kin_cat_dom | SUPERFAMILY | Glutamine synthetase/guanido kinase, catalytic domain |
GCS | PANTHER | Glutamate-cysteine ligase catalytic subunit |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
magnesium ion binding | Orthology | molecular function |
catalytic activity | Orthology | molecular function |
ATP binding | Orthology | molecular function |
cytosol | Orthology | cellular component |
response to oxidative stress | Orthology | biological process |
ligase activity | Orthology | molecular function |
negative regulation of apoptotic process | Orthology | biological process |
negative regulation of transcription, DNA-templated | Orthology | biological process |
protein heterodimerization activity | Orthology | molecular function |
coenzyme binding | Orthology | molecular function |
cellular metabolic process | Orthology | biological process |
peptide metabolic process | Orthology | biological process |
developmental process | Orthology | biological process |
organelle organization | Orthology | biological process |
apoptotic process | Orthology | biological process |
response to stress | Orthology | biological process |
response to organic substance | Orthology | biological process |
response to stimulus | Orthology | biological process |
small molecule binding | Orthology | molecular function |
anion binding | Orthology | molecular function |
cytoplasmic part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
protein ubiquitination | Orthology | biological process |
proteolysis | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
adenyl ribonucleotide binding | Orthology | molecular function |
cell | Orthology | cellular component |
mitochondrion | Orthology | cellular component |
cell surface receptor signaling pathway | Orthology | biological process |
negative regulation of signal transduction | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 575 | 0.0 |
magnesium ion binding | Hs | molecular function | 575 | 0.0 |
catalytic activity | Hs | molecular function | 575 | 0.0 |
glutamate-cysteine ligase activity | Hs | molecular function | 575 | 0.0 |
ATP binding | Hs | molecular function | 575 | 0.0 |
cytosol | Hs | cellular component | 575 | 0.0 |
glutamate binding | Hs | molecular function | 575 | 0.0 |
ligase activity | Hs | molecular function | 575 | 0.0 |
glutamate-cysteine ligase complex | Hs | cellular component | 575 | 0.0 |
ADP binding | Hs | molecular function | 575 | 0.0 |
protein heterodimerization activity | Hs | molecular function | 575 | 0.0 |
coenzyme binding | Hs | molecular function | 575 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
catalytic activity | SUPERFAMILY | molecular function | 1.86E-32 |
glutamate-cysteine ligase activity | PANTHER | molecular function | 2.5E-154 |
glutathione biosynthetic process | PANTHER | biological process | 2.5E-154 |