Gene Card
Best human hits
ARHGAP1; ARHGAP8; PRR5-ARHGAP8
Species
Unique Gene ID
Phfumi.g00005549
Gene Model ID
Phfumi.CG.MTP2014.S3228.g05549
Location
S3228:4439..9317
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Rho_GTPase_activation_prot | SUPERFAMILY | Rho GTPase activation protein |
CRAL-TRIO_dom_sf | Gene3D | CRAL-TRIO lipid binding domain superfamily |
CRAL-TRIO_dom | SMART | CRAL-TRIO lipid binding domain |
CRAL-TRIO_dom | Pfam | CRAL-TRIO lipid binding domain |
RhoGAP_dom | Pfam | Rho GTPase-activating protein domain |
CRAL-TRIO_dom | CDD | CRAL-TRIO lipid binding domain |
CRAL-TRIO_dom | ProSiteProfiles | CRAL-TRIO lipid binding domain |
CRAL-TRIO_dom_sf | SUPERFAMILY | CRAL-TRIO lipid binding domain superfamily |
Rho_GTPase_activation_prot | Gene3D | Rho GTPase activation protein |
RhoGAP_dom | ProSiteProfiles | Rho GTPase-activating protein domain |
GO Term | Annotation Origin | Type |
---|---|---|
GTPase activator activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
cytoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
signal transduction | Orthology | biological process |
small GTPase mediated signal transduction | Orthology | biological process |
positive regulation of signal transduction | Orthology | biological process |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
regulation of GTPase activity | Orthology | biological process |
positive regulation of GTPase activity | Orthology | biological process |
perinuclear region of cytoplasm | Orthology | cellular component |
extracellular exosome | Orthology | cellular component |
intracellular organelle part | Orthology | cellular component |
whole membrane | Orthology | cellular component |
endosome | Orthology | cellular component |
bounding membrane of organelle | Orthology | cellular component |
intracellular transport | Orthology | biological process |
enzyme binding | Orthology | molecular function |
protein transport | Orthology | biological process |
metal ion transport | Orthology | biological process |
cell adhesion molecule binding | Orthology | molecular function |
regulation of signal transduction | Orthology | biological process |
intracellular signal transduction | Orthology | biological process |
protein phosphorylation | Orthology | biological process |
transmembrane transport | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
SH3/SH2 adaptor activity | Hs | molecular function |
GTPase activator activity | Hs | molecular function |
protein binding | Hs | molecular function |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
signal transduction | Hs | biological process |
small GTPase mediated signal transduction | Hs | biological process |
Rho protein signal transduction | Hs | biological process |
positive regulation of signal transduction | Hs | biological process |
endosome membrane | Hs | cellular component |
membrane | Hs | cellular component |
integral component of membrane | Hs | cellular component |
endosomal transport | Hs | biological process |
SH3 domain binding | Hs | molecular function |
Rab GTPase binding | Hs | molecular function |
transferrin transport | Hs | biological process |
regulation of GTPase activity | Hs | biological process |
positive regulation of GTPase activity | Hs | biological process |
cadherin binding | Hs | molecular function |
perinuclear region of cytoplasm | Hs | cellular component |
regulation of small GTPase mediated signal transduction | Hs | biological process |
extracellular exosome | Hs | cellular component |
positive regulation of ERK1 and ERK2 cascade | Hs | biological process |
sorting endosome | Hs | cellular component |
ferric iron import across plasma membrane | Hs | biological process |
negative regulation of endocytic recycling | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
SH3/SH2 adaptor activity | Hs | molecular function | 264 | 3.88e-86 |
GTPase activator activity | Hs | molecular function | 264 | 3.88e-86 |
protein binding | Hs | molecular function | 264 | 3.88e-86 |
cytoplasm | Hs | cellular component | 264 | 3.88e-86 |
cytosol | Hs | cellular component | 264 | 3.88e-86 |
endosome membrane | Hs | cellular component | 264 | 3.88e-86 |
membrane | Hs | cellular component | 264 | 3.88e-86 |
integral component of membrane | Hs | cellular component | 264 | 3.88e-86 |
SH3 domain binding | Hs | molecular function | 264 | 3.88e-86 |
Rab GTPase binding | Hs | molecular function | 264 | 3.88e-86 |
cadherin binding | Hs | molecular function | 264 | 3.88e-86 |
perinuclear region of cytoplasm | Hs | cellular component | 264 | 3.88e-86 |
extracellular exosome | Hs | cellular component | 264 | 3.88e-86 |
sorting endosome | Hs | cellular component | 264 | 3.88e-86 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
signal transduction | Gene3D | biological process | 1.6E-14 |