Gene Card
Best human hits
PAK1; PAK2; PAK3
Species
Unique Gene ID
Phfumi.g00004051
Gene Model ID
Phfumi.CG.MTP2014.S1729.g04051
Location
S1729:7357..9991
Transcript Models and Sequences
Phfumi.CG.MTP2014.S1729.g04051.01.t
Phfumi.CG.MTP2014.S1729.g04051.02.t
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
6 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
| Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
| Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
| Prot_kinase_dom | SMART | Protein kinase domain |
| Prot_kinase_dom | Pfam | Protein kinase domain |
| Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
GOSlim
40 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| nucleotide binding | Blast | molecular function |
| catalytic activity | Blast | molecular function |
| protein kinase activity | Blast | molecular function |
| protein serine/threonine kinase activity | Blast | molecular function |
| protein binding | Blast | molecular function |
| ATP binding | Blast | molecular function |
| nucleus | Blast | cellular component |
| cytoplasm | Blast | cellular component |
| endosome | Blast | cellular component |
| cytosol | Blast | cellular component |
| plasma membrane | Blast | cellular component |
| focal adhesion | Blast | cellular component |
| protein phosphorylation | InterProScan | biological process |
| membrane | Blast | cellular component |
| kinase activity | Blast | molecular function |
| transferase activity | Blast | molecular function |
| protein kinase binding | Blast | molecular function |
| lamellipodium | Blast | cellular component |
| cell junction | Blast | cellular component |
| axon | Blast | cellular component |
| nuclear membrane | Blast | cellular component |
| macromolecular complex | Blast | cellular component |
| identical protein binding | Blast | molecular function |
| cell projection | Blast | cellular component |
| metal ion binding | Blast | molecular function |
| perinuclear region of cytoplasm | Blast | cellular component |
| plasma membrane region | Blast | cellular component |
| cell leading edge | Blast | cellular component |
| positive regulation of catalytic activity | Blast | biological process |
| intracellular signal transduction | Blast | biological process |
| positive regulation of signal transduction | Blast | biological process |
| macromolecular complex binding | Blast | molecular function |
| enzyme binding | Blast | molecular function |
| organelle part | Blast | cellular component |
| cytoplasmic part | Blast | cellular component |
| intracellular non-membrane-bounded organelle | Blast | cellular component |
| enzyme activator activity | Blast | molecular function |
| cytoskeletal part | Blast | cellular component |
| cell projection membrane | Blast | cellular component |
| cell adhesion molecule binding | Blast | molecular function |
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
42 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| nucleotide binding | Hs | molecular function | 476 | 3.81e-168 |
| ruffle | Hs | cellular component | 473 | 3.74e-167 |
| catalytic activity | Hs | molecular function | 476 | 3.81e-168 |
| protein kinase activity | Hs | molecular function | 476 | 3.81e-168 |
| protein serine/threonine kinase activity | Hs | molecular function | 476 | 3.81e-168 |
| MAP kinase kinase activity | Hs | molecular function | 476 | 3.81e-168 |
| protein binding | Hs | molecular function | 476 | 3.81e-168 |
| collagen binding | Hs | molecular function | 473 | 3.74e-167 |
| ATP binding | Hs | molecular function | 476 | 3.81e-168 |
| nucleus | Hs | cellular component | 453 | 8.21e-160 |
| cytoplasm | Hs | cellular component | 476 | 3.81e-168 |
| endosome | Hs | cellular component | 476 | 3.81e-168 |
| cytosol | Hs | cellular component | 476 | 3.81e-168 |
| plasma membrane | Hs | cellular component | 476 | 3.81e-168 |
| cell-cell junction | Hs | cellular component | 473 | 3.74e-167 |
| focal adhesion | Hs | cellular component | 473 | 3.74e-167 |
| intercalated disc | Hs | cellular component | 473 | 3.74e-167 |
| membrane | Hs | cellular component | 473 | 3.74e-167 |
| kinase activity | Hs | molecular function | 476 | 3.81e-168 |
| transferase activity | Hs | molecular function | 476 | 3.81e-168 |
| Rho GTPase binding | Hs | molecular function | 476 | 3.81e-168 |
| SH3 domain binding | Hs | molecular function | 476 | 3.81e-168 |
| protein kinase binding | Hs | molecular function | 473 | 3.74e-167 |
| Z disc | Hs | cellular component | 473 | 3.74e-167 |
| lamellipodium | Hs | cellular component | 473 | 3.74e-167 |
| cell junction | Hs | cellular component | 473 | 3.74e-167 |
| protein tyrosine kinase activator activity | Hs | molecular function | 453 | 8.21e-160 |
| axon | Hs | cellular component | 473 | 3.74e-167 |
| dendrite | Hs | cellular component | 473 | 3.74e-167 |
| small GTPase binding | Hs | molecular function | 453 | 8.21e-160 |
| filamentous actin | Hs | cellular component | 473 | 3.74e-167 |
| nuclear membrane | Hs | cellular component | 473 | 3.74e-167 |
| ruffle membrane | Hs | cellular component | 473 | 3.74e-167 |
| macromolecular complex | Hs | cellular component | 473 | 3.74e-167 |
| identical protein binding | Hs | molecular function | 453 | 8.21e-160 |
| cell projection | Hs | cellular component | 473 | 3.74e-167 |
| cadherin binding | Hs | molecular function | 453 | 8.21e-160 |
| metal ion binding | Hs | molecular function | 476 | 3.81e-168 |
| Rac GTPase binding | Hs | molecular function | 476 | 3.81e-168 |
| perinuclear region of cytoplasm | Hs | cellular component | 453 | 8.21e-160 |
| GTPase binding | Hs | molecular function | 476 | 3.81e-168 |
| invadopodium | Hs | cellular component | 473 | 3.74e-167 |
GO (InterProScan)
3 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein kinase activity | SMART | molecular function | 2.1E-89 |
| ATP binding | SMART | molecular function | 2.1E-89 |
| protein phosphorylation | SMART | biological process | 2.1E-89 |
