Gene Card
Best human hits
SORBS1; SORBS2; SORBS3
Species
Unique Gene ID
Phfumi.g00003779
Gene Model ID
Phfumi.CG.MTP2014.S1488.g03779
Location
S1488:6220..9184
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
SH3_domain | SMART | SH3 domain |
SH3-like_dom_sf | SUPERFAMILY | SH3-like domain superfamily |
SH3_domain | PRINTS | SH3 domain |
SH3_domain | Pfam | SH3 domain |
SH3_domain | ProSiteProfiles | SH3 domain |
Sorbin_SH3 | PANTHER | Sorbin and SH3 domain-containing protein |
GO Term | Annotation Origin | Type |
---|---|---|
negative regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
nucleic acid binding | Blast | molecular function |
RNA binding | Blast | molecular function |
actin binding | Blast | molecular function |
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Blast | cellular component |
cytoplasm | Orthology | cellular component |
centrosome | Blast | cellular component |
cytosol | Orthology | cellular component |
cytoskeleton | Orthology | cellular component |
plasma membrane | Blast | cellular component |
adherens junction | Blast | cellular component |
cell-substrate adherens junction | Blast | cellular component |
focal adhesion | Orthology | cellular component |
cell adhesion | Orthology | biological process |
cytoskeletal protein binding | Orthology | molecular function |
transcription factor binding | Orthology | molecular function |
positive regulation of signal transduction | Orthology | biological process |
membrane | Blast | cellular component |
apical plasma membrane | Blast | cellular component |
lamellipodium | Blast | cellular component |
cell junction | Orthology | cellular component |
cell projection | Blast | cellular component |
membrane raft | Blast | cellular component |
perinuclear region of cytoplasm | Blast | cellular component |
organelle organization | Orthology | biological process |
structural molecule activity | Orthology | molecular function |
intracellular signal transduction | Orthology | biological process |
protein phosphorylation | Orthology | biological process |
cytoskeletal part | Blast | cellular component |
receptor binding | Blast | molecular function |
macromolecular complex binding | Blast | molecular function |
integral component of plasma membrane | Blast | cellular component |
macromolecular complex | Blast | cellular component |
nuclear lumen | Blast | cellular component |
organelle part | Blast | cellular component |
cytoplasmic part | Blast | cellular component |
intracellular non-membrane-bounded organelle | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
negative regulation of transcription from RNA polymerase II promoter | Hs | biological process |
structural constituent of cytoskeleton | Hs | molecular function |
protein binding | Hs | molecular function |
nucleus | Hs | cellular component |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
cytoskeleton | Hs | cellular component |
focal adhesion | Hs | cellular component |
muscle contraction | Hs | biological process |
actin filament organization | Hs | biological process |
cell adhesion | Hs | biological process |
transcription factor binding | Hs | molecular function |
vinculin binding | Hs | molecular function |
cell junction | Hs | cellular component |
cell-substrate adhesion | Hs | biological process |
positive regulation of MAPK cascade | Hs | biological process |
positive regulation of cytoskeleton organization | Hs | biological process |
positive regulation of stress fiber assembly | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
stress fiber | Hs | cellular component | 127 | 1.80e-33 |
nucleic acid binding | Hs | molecular function | 118 | 3.89e-30 |
RNA binding | Hs | molecular function | 118 | 3.89e-30 |
actin binding | Hs | molecular function | 127 | 1.80e-33 |
SH3/SH2 adaptor activity | Hs | molecular function | 127 | 1.80e-33 |
insulin receptor binding | Hs | molecular function | 127 | 1.80e-33 |
structural constituent of cytoskeleton | Hs | molecular function | 118 | 3.89e-30 |
protein binding | Hs | molecular function | 127 | 1.80e-33 |
nucleus | Hs | cellular component | 127 | 1.80e-33 |
nucleoplasm | Hs | cellular component | 118 | 3.89e-30 |
cytoplasm | Hs | cellular component | 127 | 1.80e-33 |
centrosome | Hs | cellular component | 127 | 1.80e-33 |
cytosol | Hs | cellular component | 127 | 1.80e-33 |
cytoskeleton | Hs | cellular component | 127 | 1.80e-33 |
plasma membrane | Hs | cellular component | 127 | 1.80e-33 |
insulin receptor complex | Hs | cellular component | 127 | 1.80e-33 |
adherens junction | Hs | cellular component | 127 | 1.80e-33 |
cell-cell adherens junction | Hs | cellular component | 127 | 1.80e-33 |
zonula adherens | Hs | cellular component | 127 | 1.80e-33 |
cell-substrate adherens junction | Hs | cellular component | 127 | 1.80e-33 |
focal adhesion | Hs | cellular component | 127 | 1.80e-33 |
cytoskeletal protein binding | Hs | molecular function | 127 | 1.80e-33 |
cytoskeletal adaptor activity | Hs | molecular function | 118 | 3.89e-30 |
transcription factor binding | Hs | molecular function | 114 | 4.49e-29 |
structural constituent of muscle | Hs | molecular function | 118 | 3.89e-30 |
actin cytoskeleton | Hs | cellular component | 118 | 3.89e-30 |
membrane | Hs | cellular component | 127 | 1.80e-33 |
apical plasma membrane | Hs | cellular component | 118 | 3.89e-30 |
nuclear matrix | Hs | cellular component | 127 | 1.80e-33 |
vinculin binding | Hs | molecular function | 114 | 4.49e-29 |
Z disc | Hs | cellular component | 118 | 3.89e-30 |
lamellipodium | Hs | cellular component | 118 | 3.89e-30 |
cell junction | Hs | cellular component | 127 | 1.80e-33 |
cell projection | Hs | cellular component | 118 | 3.89e-30 |
membrane raft | Hs | cellular component | 127 | 1.80e-33 |
perinuclear region of cytoplasm | Hs | cellular component | 118 | 3.89e-30 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein binding | SUPERFAMILY | molecular function | 6.69E-17 |
actin filament organization | PANTHER | biological process | 8.6E-37 |