Gene Card
Best human hits
EPHA4; EPHA7; EPHB1
Species
Unique Gene ID
Phfumi.g00000248
Gene Model ID
Phfumi.CG.MTP2014.S12.g00248
Location
S12:144281..157194
Transcript Models and Sequences
n/a
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Click here to see the tree inference method
InterPro
26 results
| IPR Term | Analysis | Definition |
|---|---|---|
| FN3_sf | SUPERFAMILY | Fibronectin type III superfamily |
| Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
| Tyr_kinase_cat_dom | SMART | Tyrosine-protein kinase, catalytic domain |
| SAM/pointed_sf | SUPERFAMILY | Sterile alpha motif/pointed domain superfamily |
| SAM | Pfam | Sterile alpha motif domain |
| FN3_dom | CDD | Fibronectin type III |
| Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
| Ig-like_fold | Gene3D | Immunoglobulin-like fold |
| FN3_dom | Pfam | Fibronectin type III |
| Ephrin_rcpt_lig-bd_dom | ProSiteProfiles | Ephrin receptor ligand binding domain |
| SAM | ProSiteProfiles | Sterile alpha motif domain |
| Ser-Thr/Tyr_kinase_cat_dom | PRINTS | Serine-threonine/tyrosine-protein kinase, catalytic domain |
| FN3_dom | SMART | Fibronectin type III |
| Tyr_kinase_ephrin_rcpt | PIRSF | Ephrin receptor type-A /type-B |
| FN3_dom | ProSiteProfiles | Fibronectin type III |
| Galactose-bd-like_sf | Gene3D | Galactose-binding-like domain superfamily |
| Galactose-bd-like_sf | SUPERFAMILY | Galactose-binding-like domain superfamily |
| Tyr_kinase_AS | ProSitePatterns | Tyrosine-protein kinase, active site |
| Tyr-kin_ephrin_A/B_rcpt-like | SMART | Tyrosine-protein kinase ephrin type A/B receptor-like |
| Eph_TM | Pfam | Ephrin receptor, transmembrane domain |
| Ephrin_rcpt_lig-bd_dom | SMART | Ephrin receptor ligand binding domain |
| SAM | SMART | Sterile alpha motif domain |
| Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
| Ephrin_rcpt_lig-bd_dom | Pfam | Ephrin receptor ligand binding domain |
| Growth_fac_rcpt_cys_sf | SUPERFAMILY | Growth factor receptor cysteine-rich domain superfamily |
| Ser-Thr/Tyr_kinase_cat_dom | Pfam | Serine-threonine/tyrosine-protein kinase, catalytic domain |
GOSlim
49 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| nucleotide binding | Blast | molecular function |
| protein kinase activity | Blast | molecular function |
| protein binding | Blast | molecular function |
| ATP binding | Blast | molecular function |
| extracellular region | Blast | cellular component |
| cytoplasm | Blast | cellular component |
| endosome | Blast | cellular component |
| early endosome | Blast | cellular component |
| endoplasmic reticulum | Blast | cellular component |
| Golgi apparatus | Blast | cellular component |
| cytosol | Blast | cellular component |
| plasma membrane | Blast | cellular component |
| integral component of plasma membrane | Blast | cellular component |
| protein phosphorylation | InterProScan | biological process |
| axon guidance | Blast | biological process |
| cell surface | Blast | cellular component |
| membrane | Blast | cellular component |
| integral component of membrane | Blast | cellular component |
| kinase activity | Blast | molecular function |
| transferase activity | Blast | molecular function |
| cell junction | Blast | cellular component |
| axon | Blast | cellular component |
| identical protein binding | Blast | molecular function |
| cell projection | Blast | cellular component |
| neuronal cell body | Blast | cellular component |
| cell body | Blast | cellular component |
| membrane raft | Blast | cellular component |
| synapse | Blast | cellular component |
| postsynaptic membrane | Blast | cellular component |
| extracellular exosome | Blast | cellular component |
| transmembrane signaling receptor activity | Blast | molecular function |
| cell surface receptor signaling pathway | Blast | biological process |
| whole membrane | Blast | cellular component |
| mitochondrial membrane | Blast | cellular component |
| bounding membrane of organelle | Blast | cellular component |
| organelle | Blast | cellular component |
| postsynapse | Blast | cellular component |
| neuron part | Blast | cellular component |
| plasma membrane region | Blast | cellular component |
| cytoskeletal part | Blast | cellular component |
| intracellular organelle part | Blast | cellular component |
| cell projection part | Blast | cellular component |
| synapse part | Blast | cellular component |
| receptor binding | Blast | molecular function |
| molecular function regulator | Blast | molecular function |
| regulation of signal transduction | Blast | biological process |
| chemotaxis | Blast | biological process |
| signaling receptor activity | Blast | molecular function |
| protein kinase binding | Blast | molecular function |
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
51 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| nucleotide binding | Hs | molecular function | 802 | 0.0 |
| protein kinase activity | Hs | molecular function | 802 | 0.0 |
| protein tyrosine kinase activity | Hs | molecular function | 802 | 0.0 |
| transmembrane receptor protein tyrosine kinase activity | Hs | molecular function | 802 | 0.0 |
| ephrin receptor activity | Hs | molecular function | 802 | 0.0 |
| GPI-linked ephrin receptor activity | Hs | molecular function | 786 | 0.0 |
| transmembrane-ephrin receptor activity | Hs | molecular function | 802 | 0.0 |
| protein binding | Hs | molecular function | 802 | 0.0 |
| ATP binding | Hs | molecular function | 802 | 0.0 |
| extracellular region | Hs | cellular component | 802 | 0.0 |
| cytoplasm | Hs | cellular component | 802 | 0.0 |
| mitochondrial outer membrane | Hs | cellular component | 786 | 0.0 |
| endosome | Hs | cellular component | 802 | 0.0 |
| early endosome | Hs | cellular component | 786 | 0.0 |
| endoplasmic reticulum | Hs | cellular component | 802 | 0.0 |
| Golgi apparatus | Hs | cellular component | 786 | 0.0 |
| cytosol | Hs | cellular component | 802 | 0.0 |
| plasma membrane | Hs | cellular component | 802 | 0.0 |
| integral component of plasma membrane | Hs | cellular component | 802 | 0.0 |
| axon guidance receptor activity | Hs | molecular function | 802 | 0.0 |
| cell surface | Hs | cellular component | 786 | 0.0 |
| postsynaptic density | Hs | cellular component | 786 | 0.0 |
| membrane | Hs | cellular component | 802 | 0.0 |
| integral component of membrane | Hs | cellular component | 802 | 0.0 |
| kinase activity | Hs | molecular function | 802 | 0.0 |
| transferase activity | Hs | molecular function | 802 | 0.0 |
| cell junction | Hs | cellular component | 786 | 0.0 |
| filopodium | Hs | cellular component | 786 | 0.0 |
| axon | Hs | cellular component | 802 | 0.0 |
| dendrite | Hs | cellular component | 802 | 0.0 |
| neuromuscular junction | Hs | cellular component | 786 | 0.0 |
| early endosome membrane | Hs | cellular component | 802 | 0.0 |
| filopodium tip | Hs | cellular component | 802 | 0.0 |
| PH domain binding | Hs | molecular function | 786 | 0.0 |
| identical protein binding | Hs | molecular function | 786 | 0.0 |
| cell projection | Hs | cellular component | 802 | 0.0 |
| neuronal cell body | Hs | cellular component | 786 | 0.0 |
| dendritic spine | Hs | cellular component | 786 | 0.0 |
| dendritic shaft | Hs | cellular component | 786 | 0.0 |
| perikaryon | Hs | cellular component | 786 | 0.0 |
| axon terminus | Hs | cellular component | 786 | 0.0 |
| axonal growth cone | Hs | cellular component | 786 | 0.0 |
| cell body | Hs | cellular component | 786 | 0.0 |
| membrane raft | Hs | cellular component | 802 | 0.0 |
| synapse | Hs | cellular component | 786 | 0.0 |
| postsynaptic membrane | Hs | cellular component | 786 | 0.0 |
| chemorepellent activity | Hs | molecular function | 786 | 0.0 |
| ephrin receptor binding | Hs | molecular function | 786 | 0.0 |
| extracellular exosome | Hs | cellular component | 802 | 0.0 |
| DH domain binding | Hs | molecular function | 786 | 0.0 |
| protein tyrosine kinase binding | Hs | molecular function | 786 | 0.0 |
GO (InterProScan)
8 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein kinase activity | Pfam | molecular function | 4.6E-93 |
| protein tyrosine kinase activity | SMART | molecular function | 1.2E-130 |
| ephrin receptor activity | PIRSF | molecular function | 0.0 |
| protein binding | SMART | molecular function | 1.5E-72 |
| ATP binding | PIRSF | molecular function | 0.0 |
| integral component of plasma membrane | PIRSF | cellular component | 0.0 |
| protein phosphorylation | PIRSF | biological process | 0.0 |
| transmembrane receptor protein tyrosine kinase signaling pathway | PIRSF | biological process | 0.0 |
