Gene Card
Best human hits
DBH; MOXD1; PAM
Unique Gene ID
Cirobu.g00016289
Gene Model ID
NCBI:KH.100181051
Location
KhC7:1170743..1180382
Transcript Models and Sequences
n/a
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Click here to see the tree inference method
InterPro
10 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Cu2_monoox_C | Pfam | Copper type II ascorbate-dependent monooxygenase, C-terminal |
| Cu2_ascorb_mOase_N_sf | Gene3D | Copper type II, ascorbate-dependent monooxygenase, N-terminal domain superfamily |
| DOMON_domain | ProSiteProfiles | DOMON domain |
| PHM/PNGase_F_dom_sf | SUPERFAMILY | PHM/PNGase F domain superfamily |
| DOMON_domain | SMART | DOMON domain |
| DOMON_domain | Pfam | DOMON domain |
| Tbh/DBH | PRINTS | Tyramine beta-hydroxylase/Dopamine beta-hydroxylase |
| CHD_cytochrome_sf | Gene3D | CHD, cytochrome domain superfamily |
| Cu2_ascorb_mOase_N | Pfam | Copper type II, ascorbate-dependent monooxygenase, N-terminal |
| Cu2_ascorb_mOase-like_C | Gene3D | Copper type II, ascorbate-dependent monooxygenase-like, C-terminal |
GOSlim
33 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| catalytic activity | Blast | molecular function |
| calcium ion binding | Blast | molecular function |
| protein binding | Blast | molecular function |
| extracellular region | Blast | cellular component |
| extracellular space | Blast | cellular component |
| cytoplasm | Blast | cellular component |
| endoplasmic reticulum | Blast | cellular component |
| endoplasmic reticulum membrane | Blast | cellular component |
| microtubule organizing center | Blast | cellular component |
| plasma membrane | Blast | cellular component |
| zinc ion binding | Blast | molecular function |
| cell surface | Blast | cellular component |
| membrane | Blast | cellular component |
| integral component of membrane | Blast | cellular component |
| protein kinase binding | Blast | molecular function |
| cytoplasmic vesicle | Blast | cellular component |
| neuron projection | Blast | cellular component |
| neuronal cell body | Blast | cellular component |
| intracellular membrane-bounded organelle | Blast | cellular component |
| metal ion binding | Blast | molecular function |
| perinuclear region of cytoplasm | Blast | cellular component |
| oxidation-reduction process | Blast | biological process |
| extracellular exosome | Blast | cellular component |
| transition metal ion binding | Blast | molecular function |
| Golgi apparatus part | Blast | cellular component |
| endomembrane system | Blast | cellular component |
| intracellular organelle part | Blast | cellular component |
| whole membrane | Blast | cellular component |
| bounding membrane of organelle | Blast | cellular component |
| small molecule binding | Blast | molecular function |
| anion binding | Blast | molecular function |
| coenzyme binding | Blast | molecular function |
| intracellular organelle lumen | Blast | cellular component |
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
39 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| catalytic activity | Hs | molecular function | 355 | 7.22e-115 |
| monooxygenase activity | Hs | molecular function | 355 | 7.22e-115 |
| dopamine beta-monooxygenase activity | Hs | molecular function | 355 | 7.22e-115 |
| peptidylglycine monooxygenase activity | Hs | molecular function | 70.1 | 2.67e-12 |
| peptidylamidoglycolate lyase activity | Hs | molecular function | 70.1 | 2.67e-12 |
| copper ion binding | Hs | molecular function | 355 | 7.22e-115 |
| calcium ion binding | Hs | molecular function | 70.1 | 2.67e-12 |
| protein binding | Hs | molecular function | 355 | 7.22e-115 |
| extracellular region | Hs | cellular component | 222 | 3.57e-64 |
| extracellular space | Hs | cellular component | 355 | 7.22e-115 |
| cytoplasm | Hs | cellular component | 222 | 3.57e-64 |
| endoplasmic reticulum | Hs | cellular component | 355 | 7.22e-115 |
| endoplasmic reticulum membrane | Hs | cellular component | 355 | 7.22e-115 |
| trans-Golgi network | Hs | cellular component | 70.1 | 2.67e-12 |
| microtubule organizing center | Hs | cellular component | 222 | 3.57e-64 |
| plasma membrane | Hs | cellular component | 70.1 | 2.67e-12 |
| zinc ion binding | Hs | molecular function | 70.1 | 2.67e-12 |
| cell surface | Hs | cellular component | 70.1 | 2.67e-12 |
| membrane | Hs | cellular component | 355 | 7.22e-115 |
| integral component of membrane | Hs | cellular component | 355 | 7.22e-115 |
| oxidoreductase activity | Hs | molecular function | 355 | 7.22e-115 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen | Hs | molecular function | 355 | 7.22e-115 |
| lyase activity | Hs | molecular function | 70.1 | 2.67e-12 |
| protein kinase binding | Hs | molecular function | 70.1 | 2.67e-12 |
| secretory granule | Hs | cellular component | 70.1 | 2.67e-12 |
| transport vesicle membrane | Hs | cellular component | 222 | 3.57e-64 |
| secretory granule membrane | Hs | cellular component | 355 | 7.22e-115 |
| cytoplasmic vesicle | Hs | cellular component | 222 | 3.57e-64 |
| L-ascorbic acid binding | Hs | molecular function | 222 | 3.57e-64 |
| chromaffin granule lumen | Hs | cellular component | 222 | 3.57e-64 |
| secretory granule lumen | Hs | cellular component | 222 | 3.57e-64 |
| chromaffin granule membrane | Hs | cellular component | 222 | 3.57e-64 |
| neuron projection | Hs | cellular component | 70.1 | 2.67e-12 |
| neuronal cell body | Hs | cellular component | 70.1 | 2.67e-12 |
| perikaryon | Hs | cellular component | 70.1 | 2.67e-12 |
| intracellular membrane-bounded organelle | Hs | cellular component | 222 | 3.57e-64 |
| metal ion binding | Hs | molecular function | 355 | 7.22e-115 |
| perinuclear region of cytoplasm | Hs | cellular component | 70.1 | 2.67e-12 |
| extracellular exosome | Hs | cellular component | 70.1 | 2.67e-12 |
GO (InterProScan)
5 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| catalytic activity | SUPERFAMILY | molecular function | 6.8E-38 |
| monooxygenase activity | Pfam | molecular function | 2.3E-43 |
| copper ion binding | Pfam | molecular function | 2.3E-43 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen | Pfam | molecular function | 2.3E-43 |
| oxidation-reduction process | Pfam | biological process | 2.3E-43 |
