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GENE CARD

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Gene Card

Best human hits

EZR; MSN; RDX

Species

M.oculata

Unique Gene ID

Moocul.g00006746

Gene Model ID

Moocul.CG.ELv1_2.S87201.g06746

Location

S87201:7109..24265

Transcript Models and Sequences

  Moocul.CG.ELv1_2.S87201.g06746.01.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

15 results

IPR Term Analysis Definition
PH-like_dom_sf Gene3D PH-like domain superfamily
ERM PIRSF Ezrin/radixin/moesin
FERM_central Pfam FERM central domain
Ubiquitin-like_domsf SUPERFAMILY Ubiquitin-like domain superfamily
FERM_2 SUPERFAMILY FERM superfamily, second domain
FERM_central CDD FERM central domain
FERM_PH-like_C Pfam FERM, C-terminal PH-like domain
Band_41_domain PRINTS Band 4.1 domain
FERM_N Pfam FERM, N-terminal
Band_41_domain SMART Band 4.1 domain
Ez/rad/moesin-like PRINTS Ezrin/radixin/moesin-like
FERM_PH-like_C SMART FERM, C-terminal PH-like domain
FERM_CS ProSitePatterns FERM conserved site
FERM/acyl-CoA-bd_prot_sf Gene3D FERM/acyl-CoA-binding protein superfamily
FERM_domain ProSiteProfiles FERM domain

GOSlim

No result

GO Term Annotation Origin Type

GO (Orthology)

122 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
fibrillar center Hs cellular component
ruffle Hs cellular component
immunological synapse Hs cellular component
uropod Hs cellular component
sphingosine-1-phosphate signaling pathway Hs biological process
RNA binding Hs molecular function
double-stranded RNA binding Hs molecular function
actin binding Hs molecular function
receptor binding Hs molecular function
structural constituent of cytoskeleton Hs molecular function
protein binding Hs molecular function
extracellular space Hs cellular component
intracellular Hs cellular component
nucleus Hs cellular component
cytoplasm Hs cellular component
endosome Hs cellular component
cytosol Hs cellular component
cytoskeleton Hs cellular component
actin filament Hs cellular component
plasma membrane Hs cellular component
microvillus Hs cellular component
brush border Hs cellular component
cell-cell adherens junction Hs cellular component
focal adhesion Hs cellular component
cell cortex Hs cellular component
cytoskeleton organization Hs biological process
cytoskeletal anchoring at plasma membrane Hs biological process
axon guidance Hs biological process
microtubule binding Hs molecular function
protein C-terminus binding Hs molecular function
cytoskeletal protein binding Hs molecular function
regulation of cell shape Hs biological process
regulation of cell size Hs biological process
cell surface Hs cellular component
positive regulation of gene expression Hs biological process
protein kinase A signaling Hs biological process
actin cytoskeleton Hs cellular component
membrane Hs cellular component
basolateral plasma membrane Hs cellular component
apical plasma membrane Hs cellular component
extrinsic component of membrane Hs cellular component
enzyme binding Hs molecular function
protein kinase binding Hs molecular function
protein domain specific binding Hs molecular function
lamellipodium Hs cellular component
microvillus assembly Hs biological process
filopodium Hs cellular component
T-tubule Hs cellular component
positive regulation of cell migration Hs biological process
midbody Hs cellular component
epithelial cell differentiation Hs biological process
cortical cytoskeleton Hs cellular component
cortical actin cytoskeleton Hs cellular component
astral microtubule organization Hs biological process
pseudopodium Hs cellular component
microvillus membrane Hs cellular component
actin cytoskeleton reorganization Hs biological process
receptor internalization Hs biological process
vesicle Hs cellular component
cleavage furrow Hs cellular component
regulation of actin filament bundle assembly Hs biological process
stereocilium Hs cellular component
regulation of Rap protein signal transduction Hs biological process
ruffle membrane Hs cellular component
macromolecular complex Hs cellular component
negative regulation of homotypic cell-cell adhesion Hs biological process
protein kinase A catalytic subunit binding Hs molecular function
protein kinase A regulatory subunit binding Hs molecular function
negative regulation of GTPase activity Hs biological process
cellular protein complex localization Hs biological process
establishment or maintenance of apical/basal cell polarity Hs biological process
ciliary basal body Hs cellular component
positive regulation of multicellular organism growth Hs biological process
identical protein binding Hs molecular function
protein homodimerization activity Hs molecular function
cell projection Hs cellular component
regulation of GTPase activity Hs biological process
myelin sheath Hs cellular component
cortical microtubule organization Hs biological process
cell body Hs cellular component
microspike Hs cellular component
S100 protein binding Hs molecular function
plasma membrane raft Hs cellular component
membrane raft Hs cellular component
apical protein localization Hs biological process
apical part of cell Hs cellular component
establishment of protein localization Hs biological process
establishment of epithelial cell apical/basal polarity Hs biological process
cadherin binding Hs molecular function
negative regulation of cell size Hs biological process
filopodium assembly Hs biological process
phosphatidylinositol-mediated signaling Hs biological process
perinuclear region of cytoplasm Hs cellular component
positive regulation of protein secretion Hs biological process
cell adhesion molecule binding Hs molecular function
negative regulation of T cell receptor signaling pathway Hs biological process
leukocyte migration Hs biological process
actin filament binding Hs molecular function
barbed-end actin filament capping Hs biological process
actin filament bundle assembly Hs biological process
protein kinase A binding Hs molecular function
ATPase binding Hs molecular function
cell tip Hs cellular component
establishment of centrosome localization Hs biological process
actin filament capping Hs biological process
establishment of endothelial barrier Hs biological process
extracellular exosome Hs cellular component
negative regulation of ERK1 and ERK2 cascade Hs biological process
invadopodium Hs cellular component
cell periphery Hs cellular component
blood microparticle Hs cellular component
protein localization to plasma membrane Hs biological process
protein localization to cell cortex Hs biological process
astrocyte projection Hs cellular component
Schwann cell microvillus Hs cellular component
disordered domain specific binding Hs molecular function
cytoplasmic side of apical plasma membrane Hs cellular component
positive regulation of G1/S transition of mitotic cell cycle Hs biological process
positive regulation of protein localization to plasma membrane Hs biological process
positive regulation of cellular protein catabolic process Hs biological process
negative regulation of adherens junction organization Hs biological process

GO (Blast)

77 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
fibrillar center Hs cellular component 589 0.0
ruffle Hs cellular component 589 0.0
immunological synapse Hs cellular component 589 0.0
uropod Hs cellular component 589 0.0
RNA binding Hs molecular function 589 0.0
double-stranded RNA binding Hs molecular function 564 0.0
actin binding Hs molecular function 589 0.0
receptor binding Hs molecular function 564 0.0
structural constituent of cytoskeleton Hs molecular function 564 0.0
protein binding Hs molecular function 589 0.0
extracellular space Hs cellular component 589 0.0
intracellular Hs cellular component 589 0.0
nucleus Hs cellular component 564 0.0
cytoplasm Hs cellular component 589 0.0
endosome Hs cellular component 589 0.0
cytosol Hs cellular component 589 0.0
cytoskeleton Hs cellular component 589 0.0
actin filament Hs cellular component 589 0.0
plasma membrane Hs cellular component 589 0.0
microvillus Hs cellular component 589 0.0
brush border Hs cellular component 589 0.0
cell-cell adherens junction Hs cellular component 582 0.0
focal adhesion Hs cellular component 589 0.0
cell cortex Hs cellular component 589 0.0
microtubule binding Hs molecular function 589 0.0
protein C-terminus binding Hs molecular function 589 0.0
cytoskeletal protein binding Hs molecular function 589 0.0
cell surface Hs cellular component 564 0.0
actin cytoskeleton Hs cellular component 589 0.0
membrane Hs cellular component 589 0.0
basolateral plasma membrane Hs cellular component 589 0.0
apical plasma membrane Hs cellular component 589 0.0
extrinsic component of membrane Hs cellular component 589 0.0
enzyme binding Hs molecular function 564 0.0
protein kinase binding Hs molecular function 564 0.0
protein domain specific binding Hs molecular function 589 0.0
lamellipodium Hs cellular component 582 0.0
filopodium Hs cellular component 589 0.0
T-tubule Hs cellular component 589 0.0
midbody Hs cellular component 582 0.0
cortical cytoskeleton Hs cellular component 589 0.0
cortical actin cytoskeleton Hs cellular component 582 0.0
pseudopodium Hs cellular component 564 0.0
microvillus membrane Hs cellular component 589 0.0
vesicle Hs cellular component 589 0.0
cleavage furrow Hs cellular component 582 0.0
stereocilium Hs cellular component 582 0.0
ruffle membrane Hs cellular component 589 0.0
macromolecular complex Hs cellular component 589 0.0
protein kinase A catalytic subunit binding Hs molecular function 589 0.0
protein kinase A regulatory subunit binding Hs molecular function 589 0.0
ciliary basal body Hs cellular component 589 0.0
identical protein binding Hs molecular function 589 0.0
protein homodimerization activity Hs molecular function 582 0.0
cell projection Hs cellular component 589 0.0
myelin sheath Hs cellular component 589 0.0
cell body Hs cellular component 589 0.0
microspike Hs cellular component 589 0.0
S100 protein binding Hs molecular function 589 0.0
plasma membrane raft Hs cellular component 589 0.0
membrane raft Hs cellular component 589 0.0
apical part of cell Hs cellular component 589 0.0
cadherin binding Hs molecular function 589 0.0
perinuclear region of cytoplasm Hs cellular component 589 0.0
cell adhesion molecule binding Hs molecular function 589 0.0
actin filament binding Hs molecular function 589 0.0
protein kinase A binding Hs molecular function 589 0.0
ATPase binding Hs molecular function 589 0.0
cell tip Hs cellular component 589 0.0
extracellular exosome Hs cellular component 589 0.0
invadopodium Hs cellular component 589 0.0
cell periphery Hs cellular component 589 0.0
blood microparticle Hs cellular component 564 0.0
astrocyte projection Hs cellular component 589 0.0
Schwann cell microvillus Hs cellular component 589 0.0
disordered domain specific binding Hs molecular function 589 0.0
cytoplasmic side of apical plasma membrane Hs cellular component 589 0.0

GO (InterProScan)

3 results

GO Term Analysis Type e-value
actin binding PIRSF molecular function 1.6E-218
cytoskeleton ProSiteProfiles cellular component 80.85
cytoskeletal protein binding PRINTS molecular function 2.1E-63