Gene Card
Best human hits
FBXW7; NLE1; WDR12
Species
Unique Gene ID
Moocul.g00005167
Gene Model ID
Moocul.CG.ELv1_2.S74359.g05167
Location
S74359:139..1423
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
11 results
| IPR Term | Analysis | Definition |
|---|---|---|
| WD40_repeat_CS | ProSitePatterns | WD40 repeat, conserved site |
| WDR12/Ytm1 | Hamap | WD repeat WDR12/Ytm1 |
| WD40/YVTN_repeat-like_dom_sf | Gene3D | WD40/YVTN repeat-like-containing domain superfamily |
| WD40_repeat | ProSiteProfiles | WD40 repeat |
| WD40_repeat_dom | ProSiteProfiles | WD40-repeat-containing domain |
| WD40_repeat_dom_sf | SUPERFAMILY | WD40-repeat-containing domain superfamily |
| WD40_repeat | SMART | WD40 repeat |
| NLE | Pfam | NLE |
| Apc4_WD40_dom | Pfam | Anaphase-promoting complex subunit 4, WD40 domain |
| G-protein_beta_WD-40_rep | PRINTS | G-protein beta WD-40 repeat |
| WD40_repeat | Pfam | WD40 repeat |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
14 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Hs | biological process |
| maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Hs | biological process |
| protein binding | Hs | molecular function |
| nucleus | Hs | cellular component |
| nucleoplasm | Hs | cellular component |
| nucleolus | Hs | cellular component |
| rRNA processing | Hs | biological process |
| Notch signaling pathway | Hs | biological process |
| cell proliferation | Hs | biological process |
| preribosome, large subunit precursor | Hs | cellular component |
| ribosome biogenesis | Hs | biological process |
| ribosomal large subunit biogenesis | Hs | biological process |
| ribonucleoprotein complex binding | Hs | molecular function |
| PeBoW complex | Hs | cellular component |
GO (Blast)
19 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| ubiquitin-protein transferase activity | Hs | molecular function | 83.6 | 3.62e-17 |
| protein binding | Hs | molecular function | 391 | 3.89e-134 |
| nucleus | Hs | cellular component | 391 | 3.89e-134 |
| nucleoplasm | Hs | cellular component | 391 | 3.89e-134 |
| nucleolus | Hs | cellular component | 391 | 3.89e-134 |
| cytoplasm | Hs | cellular component | 83.6 | 3.62e-17 |
| cytosol | Hs | cellular component | 83.6 | 3.62e-17 |
| ribosome | Hs | cellular component | 82.4 | 7.40e-17 |
| SCF ubiquitin ligase complex | Hs | cellular component | 83.6 | 3.62e-17 |
| cyclin binding | Hs | molecular function | 83.6 | 3.62e-17 |
| protein binding, bridging | Hs | molecular function | 83.6 | 3.62e-17 |
| preribosome, large subunit precursor | Hs | cellular component | 391 | 3.89e-134 |
| ubiquitin protein ligase binding | Hs | molecular function | 83.6 | 3.62e-17 |
| identical protein binding | Hs | molecular function | 83.6 | 3.62e-17 |
| ribonucleoprotein complex binding | Hs | molecular function | 391 | 3.89e-134 |
| phosphothreonine residue binding | Hs | molecular function | 83.6 | 3.62e-17 |
| PeBoW complex | Hs | cellular component | 391 | 3.89e-134 |
| ubiquitin-protein transferase activator activity | Hs | molecular function | 83.6 | 3.62e-17 |
| Parkin-FBXW7-Cul1 ubiquitin ligase complex | Hs | cellular component | 83.6 | 3.62e-17 |
GO (InterProScan)
2 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein binding | Gene3D | molecular function | 8.6E-70 |
| ribosome biogenesis | Hamap | biological process | 29.973 |
