Aniseed - Gene card

Gene 'Moocul.CG.ELv1_2.S69...'

Gene Card

Best human hits

AKR1A1; AKR1B10; GCLM

Species

M.oculata

Unique Gene ID

Moocul.g00004617

Gene Model ID

Moocul.CG.ELv1_2.S69627.g04617

Location

S69627:3500..8685

Transcript Models and Sequences

Moocul.CG.ELv1_2.S69627.g04617.01.t

External Database Gene Card

External database links

No result

Collections

WashU Genome Browser

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Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

4 results

IPR Term	Analysis	Definition
Gclm	PANTHER	Glutamate--cysteine ligase regulatory subunit
NADP_OxRdtase_dom	Pfam	NADP-dependent oxidoreductase domain
NADP_OxRdtase_dom_sf	Gene3D	NADP-dependent oxidoreductase domain superfamily
NADP_OxRdtase_dom_sf	SUPERFAMILY	NADP-dependent oxidoreductase domain superfamily

GOSlim

No result

GO Term	Annotation Origin	Type

GO (Orthology)

22 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
glutamate-cysteine ligase activity	Hs	molecular function
cytosol	Hs	cellular component
cysteine metabolic process	Hs	biological process
glutamate metabolic process	Hs	biological process
glutathione metabolic process	Hs	biological process
glutathione biosynthetic process	Hs	biological process
response to oxidative stress	Hs	biological process
aging	Hs	biological process
response to nutrient	Hs	biological process
apoptotic mitochondrial changes	Hs	biological process
response to activity	Hs	biological process
glutamate-cysteine ligase complex	Hs	cellular component
enzyme regulator activity	Hs	molecular function
glutamate-cysteine ligase catalytic subunit binding	Hs	molecular function
positive regulation of glutamate-cysteine ligase activity	Hs	biological process
response to drug	Hs	biological process
negative regulation of neuron apoptotic process	Hs	biological process
protein heterodimerization activity	Hs	molecular function
regulation of blood vessel size	Hs	biological process
regulation of mitochondrial depolarization	Hs	biological process
cellular response to glucose stimulus	Hs	biological process
negative regulation of extrinsic apoptotic signaling pathway	Hs	biological process

GO (Blast)

21 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
retinal dehydrogenase activity	Hs	molecular function	41.2	4.15e-04
alditol:NADP+ 1-oxidoreductase activity	Hs	molecular function	58.9	7.21e-10
aldo-keto reductase (NADP) activity	Hs	molecular function	58.9	7.21e-10
glutamate-cysteine ligase activity	Hs	molecular function	177	4.52e-54
protein binding	Hs	molecular function	58.9	7.21e-10
extracellular region	Hs	cellular component	41.2	4.15e-04
extracellular space	Hs	cellular component	58.9	7.21e-10
lysosome	Hs	cellular component	41.2	4.15e-04
cytosol	Hs	cellular component	177	4.52e-54
alcohol dehydrogenase (NADP+) activity	Hs	molecular function	58.9	7.21e-10
electron carrier activity	Hs	molecular function	58.9	7.21e-10
apical plasma membrane	Hs	cellular component	58.9	7.21e-10
oxidoreductase activity	Hs	molecular function	58.9	7.21e-10
glutamate-cysteine ligase complex	Hs	cellular component	177	4.52e-54
enzyme regulator activity	Hs	molecular function	177	4.52e-54
glutamate-cysteine ligase catalytic subunit binding	Hs	molecular function	177	4.52e-54
geranylgeranyl reductase activity	Hs	molecular function	41.2	4.15e-04
protein heterodimerization activity	Hs	molecular function	177	4.52e-54
indanol dehydrogenase activity	Hs	molecular function	41.2	4.15e-04
L-glucuronate reductase activity	Hs	molecular function	58.9	7.21e-10
extracellular exosome	Hs	cellular component	58.9	7.21e-10

GO (InterProScan)

2 results

GO Term	Analysis	Type	e-value
glutathione biosynthetic process	PANTHER	biological process	1.3E-75
glutamate-cysteine ligase catalytic subunit binding	PANTHER	molecular function	1.3E-75