Gene Card
Best human hits
LRP1; RXFP2; SORL1
Species
Unique Gene ID
Moocul.g00003847
Gene Model ID
Moocul.CG.ELv1_2.S61030.g03847
Location
S61030:11058..15639
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
10 results
| IPR Term | Analysis | Definition |
|---|---|---|
| LDrepeatLR_classA_rpt | CDD | Low-density lipoprotein (LDL) receptor class A repeat |
| GPCR_Rhodpsn | Pfam | G protein-coupled receptor, rhodopsin-like |
| LDrepeatLR_classA_rpt | ProSiteProfiles | Low-density lipoprotein (LDL) receptor class A repeat |
| LDL_receptor-like_sf | SUPERFAMILY | LDL receptor-like superfamily |
| LDLR_class-A_CS | ProSitePatterns | Low-density lipoprotein (LDL) receptor class A, conserved site |
| TSHR/LHCGR/FSHR | PANTHER | TSH/LHCG/FSH receptor |
| LDrepeatLR_classA_rpt | SMART | Low-density lipoprotein (LDL) receptor class A repeat |
| LDrepeatLR_classA_rpt | Pfam | Low-density lipoprotein (LDL) receptor class A repeat |
| GPCR_Rhodpsn_7TM | ProSiteProfiles | GPCR, rhodopsin-like, 7TM |
| LDrepeatLR_classA_rpt | PRINTS | Low-density lipoprotein (LDL) receptor class A repeat |
| GO Term | Annotation Origin | Type |
|---|
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
55 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| Golgi membrane | Hs | cellular component | 84.0 | 3.38e-16 |
| amyloid-beta binding | Hs | molecular function | 84.0 | 3.38e-16 |
| protease binding | Hs | molecular function | 75.5 | 1.31e-13 |
| RNA binding | Hs | molecular function | 75.5 | 1.31e-13 |
| signal transducer activity | Hs | molecular function | 90.9 | 1.35e-18 |
| receptor activity | Hs | molecular function | 75.5 | 1.31e-13 |
| transmembrane signaling receptor activity | Hs | molecular function | 84.0 | 3.38e-16 |
| G-protein coupled receptor activity | Hs | molecular function | 90.9 | 1.35e-18 |
| low-density lipoprotein receptor activity | Hs | molecular function | 84.0 | 3.38e-16 |
| scavenger receptor activity | Hs | molecular function | 75.5 | 1.31e-13 |
| calcium ion binding | Hs | molecular function | 75.5 | 1.31e-13 |
| protein binding | Hs | molecular function | 90.9 | 1.35e-18 |
| extracellular region | Hs | cellular component | 84.0 | 3.38e-16 |
| extracellular space | Hs | cellular component | 84.0 | 3.38e-16 |
| intracellular | Hs | cellular component | 90.9 | 1.35e-18 |
| nucleus | Hs | cellular component | 75.5 | 1.31e-13 |
| nuclear envelope lumen | Hs | cellular component | 84.0 | 3.38e-16 |
| cytoplasm | Hs | cellular component | 75.5 | 1.31e-13 |
| lysosomal membrane | Hs | cellular component | 75.5 | 1.31e-13 |
| endosome | Hs | cellular component | 84.0 | 3.38e-16 |
| early endosome | Hs | cellular component | 84.0 | 3.38e-16 |
| endoplasmic reticulum | Hs | cellular component | 84.0 | 3.38e-16 |
| Golgi apparatus | Hs | cellular component | 84.0 | 3.38e-16 |
| trans-Golgi network | Hs | cellular component | 84.0 | 3.38e-16 |
| plasma membrane | Hs | cellular component | 90.9 | 1.35e-18 |
| integral component of plasma membrane | Hs | cellular component | 84.0 | 3.38e-16 |
| clathrin-coated pit | Hs | cellular component | 75.5 | 1.31e-13 |
| focal adhesion | Hs | cellular component | 75.5 | 1.31e-13 |
| endosome membrane | Hs | cellular component | 84.0 | 3.38e-16 |
| membrane | Hs | cellular component | 90.9 | 1.35e-18 |
| integral component of membrane | Hs | cellular component | 90.9 | 1.35e-18 |
| basolateral plasma membrane | Hs | cellular component | 75.5 | 1.31e-13 |
| protein-hormone receptor activity | Hs | molecular function | 90.9 | 1.35e-18 |
| alpha-2 macroglobulin receptor activity | Hs | molecular function | 75.5 | 1.31e-13 |
| peptide hormone binding | Hs | molecular function | 90.9 | 1.35e-18 |
| clathrin-coated vesicle | Hs | cellular component | 75.5 | 1.31e-13 |
| low-density lipoprotein particle binding | Hs | molecular function | 84.0 | 3.38e-16 |
| apolipoprotein receptor activity | Hs | molecular function | 75.5 | 1.31e-13 |
| ADP-ribosylation factor binding | Hs | molecular function | 84.0 | 3.38e-16 |
| dendrite | Hs | cellular component | 75.5 | 1.31e-13 |
| endocytic vesicle membrane | Hs | cellular component | 75.5 | 1.31e-13 |
| Golgi cisterna | Hs | cellular component | 84.0 | 3.38e-16 |
| clathrin heavy chain binding | Hs | molecular function | 75.5 | 1.31e-13 |
| apolipoprotein binding | Hs | molecular function | 75.5 | 1.31e-13 |
| low-density lipoprotein particle | Hs | cellular component | 84.0 | 3.38e-16 |
| lipoprotein transporter activity | Hs | molecular function | 75.5 | 1.31e-13 |
| neuronal cell body | Hs | cellular component | 75.5 | 1.31e-13 |
| receptor complex | Hs | cellular component | 75.5 | 1.31e-13 |
| heparan sulfate proteoglycan binding | Hs | molecular function | 75.5 | 1.31e-13 |
| macromolecular complex binding | Hs | molecular function | 75.5 | 1.31e-13 |
| metal ion binding | Hs | molecular function | 75.5 | 1.31e-13 |
| recycling endosome | Hs | cellular component | 84.0 | 3.38e-16 |
| extracellular exosome | Hs | cellular component | 84.0 | 3.38e-16 |
| lipoprotein particle receptor binding | Hs | molecular function | 75.5 | 1.31e-13 |
| plasma membrane protein complex | Hs | cellular component | 75.5 | 1.31e-13 |
GO (InterProScan)
4 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| G-protein coupled receptor activity | Pfam | molecular function | 2.3E-6 |
| protein binding | PRINTS | molecular function | 1.5E-18 |
| G-protein coupled receptor signaling pathway | Pfam | biological process | 2.3E-6 |
| integral component of membrane | Pfam | cellular component | 2.3E-6 |
