Gene Card
Best human hits
HIP1; TLN1; TLN2
Species
Unique Gene ID
Moocul.g00003794
Gene Model ID
Moocul.CG.ELv1_2.S60205.g03794
Location
S60205:8132..29730
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
20 results
| IPR Term | Analysis | Definition |
|---|---|---|
| FERM_central | Pfam | FERM central domain |
| I/LWEQ_dom_sf | SUPERFAMILY | I/LWEQ domain superfamily |
| Alpha-catenin/vinculin-like_sf | SUPERFAMILY | Alpha-catenin/vinculin-like superfamily |
| Talin1/2-RS | CDD | Talin-1/2, rod-segment |
| FERM_f0 | Pfam | Talin, N-terminal F0 domain |
| Band_41_domain | SMART | Band 4.1 domain |
| PH-like_dom_sf | Gene3D | PH-like domain superfamily |
| FERM_central | CDD | FERM central domain |
| FERM_2 | SUPERFAMILY | FERM superfamily, second domain |
| FERM_N | Pfam | FERM, N-terminal |
| FERM_CS | ProSitePatterns | FERM conserved site |
| ILWEQ_dom | Pfam | I/LWEQ domain |
| ILWEQ_dom | SMART | I/LWEQ domain |
| FERM/acyl-CoA-bd_prot_sf | Gene3D | FERM/acyl-CoA-binding protein superfamily |
| ILWEQ_dom | ProDom | I/LWEQ domain |
| Vinculin-bd_dom | Pfam | Vinculin-binding site-containing domain |
| Talin_cent | Pfam | Talin, central |
| Talin_cent_sf | SUPERFAMILY | Talin, central domain superfamily |
| ILWEQ_dom | ProSiteProfiles | I/LWEQ domain |
| FERM_domain | ProSiteProfiles | FERM domain |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
36 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| ruffle | Hs | cellular component |
| phosphatidylserine binding | Hs | molecular function |
| platelet degranulation | Hs | biological process |
| actin binding | Hs | molecular function |
| integrin binding | Hs | molecular function |
| structural molecule activity | Hs | molecular function |
| structural constituent of cytoskeleton | Hs | molecular function |
| protein binding | Hs | molecular function |
| extracellular region | Hs | cellular component |
| cytoplasm | Hs | cellular component |
| cytosol | Hs | cellular component |
| cytoskeleton | Hs | cellular component |
| plasma membrane | Hs | cellular component |
| focal adhesion | Hs | cellular component |
| muscle contraction | Hs | biological process |
| cytoskeletal anchoring at plasma membrane | Hs | biological process |
| cell-cell junction assembly | Hs | biological process |
| cell-substrate junction assembly | Hs | biological process |
| cell adhesion | Hs | biological process |
| integrin-mediated signaling pathway | Hs | biological process |
| cell surface | Hs | cellular component |
| actin cytoskeleton | Hs | cellular component |
| membrane | Hs | cellular component |
| viral process | Hs | biological process |
| vinculin binding | Hs | molecular function |
| cell junction | Hs | cellular component |
| LIM domain binding | Hs | molecular function |
| cortical actin cytoskeleton organization | Hs | biological process |
| ruffle membrane | Hs | cellular component |
| phosphatidylinositol binding | Hs | molecular function |
| cell projection | Hs | cellular component |
| synapse | Hs | cellular component |
| cadherin binding | Hs | molecular function |
| actin filament binding | Hs | molecular function |
| extracellular exosome | Hs | cellular component |
| platelet aggregation | Hs | biological process |
GO (Blast)
51 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| ruffle | Hs | cellular component | 2808 | 0.0 |
| phosphatidylserine binding | Hs | molecular function | 2796 | 0.0 |
| actin binding | Hs | molecular function | 2808 | 0.0 |
| epidermal growth factor receptor binding | Hs | molecular function | 108 | 2.01e-23 |
| integrin binding | Hs | molecular function | 2796 | 0.0 |
| structural molecule activity | Hs | molecular function | 2808 | 0.0 |
| structural constituent of cytoskeleton | Hs | molecular function | 2808 | 0.0 |
| protein binding | Hs | molecular function | 2808 | 0.0 |
| phospholipid binding | Hs | molecular function | 108 | 2.01e-23 |
| extracellular region | Hs | cellular component | 2796 | 0.0 |
| nucleus | Hs | cellular component | 108 | 2.01e-23 |
| cytoplasm | Hs | cellular component | 2808 | 0.0 |
| Golgi apparatus | Hs | cellular component | 108 | 2.01e-23 |
| cytosol | Hs | cellular component | 2796 | 0.0 |
| cytoskeleton | Hs | cellular component | 2808 | 0.0 |
| plasma membrane | Hs | cellular component | 2808 | 0.0 |
| focal adhesion | Hs | cellular component | 2808 | 0.0 |
| cell surface | Hs | cellular component | 2796 | 0.0 |
| endomembrane system | Hs | cellular component | 108 | 2.01e-23 |
| actin cytoskeleton | Hs | cellular component | 2808 | 0.0 |
| membrane | Hs | cellular component | 2808 | 0.0 |
| vinculin binding | Hs | molecular function | 2796 | 0.0 |
| cell junction | Hs | cellular component | 2808 | 0.0 |
| AP-2 adaptor complex | Hs | cellular component | 108 | 2.01e-23 |
| clathrin-coated vesicle | Hs | cellular component | 108 | 2.01e-23 |
| LIM domain binding | Hs | molecular function | 2796 | 0.0 |
| clathrin binding | Hs | molecular function | 108 | 2.01e-23 |
| clathrin-coated vesicle membrane | Hs | cellular component | 108 | 2.01e-23 |
| extrinsic component of cytoplasmic side of plasma membrane | Hs | cellular component | 108 | 2.01e-23 |
| cytoplasmic vesicle | Hs | cellular component | 108 | 2.01e-23 |
| clathrin light chain binding | Hs | molecular function | 108 | 2.01e-23 |
| phosphatidylinositol-3-phosphate binding | Hs | molecular function | 108 | 2.01e-23 |
| ruffle membrane | Hs | cellular component | 2796 | 0.0 |
| phosphatidylinositol binding | Hs | molecular function | 2796 | 0.0 |
| glutamate receptor binding | Hs | molecular function | 108 | 2.01e-23 |
| AP-2 adaptor complex binding | Hs | molecular function | 108 | 2.01e-23 |
| clathrin adaptor activity | Hs | molecular function | 108 | 2.01e-23 |
| protein homodimerization activity | Hs | molecular function | 108 | 2.01e-23 |
| cell projection | Hs | cellular component | 2796 | 0.0 |
| intracellular membrane-bounded organelle | Hs | cellular component | 108 | 2.01e-23 |
| phosphatidylinositol-3,4-bisphosphate binding | Hs | molecular function | 108 | 2.01e-23 |
| synapse | Hs | cellular component | 2808 | 0.0 |
| cadherin binding | Hs | molecular function | 2796 | 0.0 |
| protein heterodimerization activity | Hs | molecular function | 108 | 2.01e-23 |
| actin filament binding | Hs | molecular function | 2808 | 0.0 |
| extracellular exosome | Hs | cellular component | 2796 | 0.0 |
| phosphatidylinositol-3,5-bisphosphate binding | Hs | molecular function | 108 | 2.01e-23 |
| presynapse | Hs | cellular component | 108 | 2.01e-23 |
| postsynapse | Hs | cellular component | 108 | 2.01e-23 |
| extrinsic component of presynaptic membrane | Hs | cellular component | 108 | 2.01e-23 |
| extrinsic component of postsynaptic membrane | Hs | cellular component | 108 | 2.01e-23 |
GO (InterProScan)
8 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| ruffle | Pfam | cellular component | 2.5E-54 |
| actin binding | SMART | molecular function | 4.2E-83 |
| structural constituent of cytoskeleton | Pfam | molecular function | 2.5E-54 |
| cytoskeleton | ProSiteProfiles | cellular component | 51.33 |
| focal adhesion | Pfam | cellular component | 2.5E-54 |
| cytoskeletal anchoring at plasma membrane | Pfam | biological process | 2.5E-54 |
| cell adhesion | SUPERFAMILY | biological process | 4.39E-37 |
| actin filament binding | SUPERFAMILY | molecular function | 4.39E-37 |
