Gene Card
Best human hits
TRAF2; TRAF4; TRAF6
Species
Unique Gene ID
Moocul.g00003727
Gene Model ID
Moocul.CG.ELv1_2.S59511.g03727
Location
S59511:43141..55211
Transcript Models and Sequences
Moocul.CG.ELv1_2.S59511.g03727.01.t
Moocul.CG.ELv1_2.S59511.g03727.02.t
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Znf_RING | SMART | Zinc finger, RING-type |
Znf_TRAF | ProSiteProfiles | Zinc finger, TRAF-type |
Znf_RING_CS | ProSitePatterns | Zinc finger, RING-type, conserved site |
TRAF-like | SUPERFAMILY | TRAF-like |
Znf_TRAF | Pfam | Zinc finger, TRAF-type |
Znf_RING/FYVE/PHD | Gene3D | Zinc finger, RING/FYVE/PHD-type |
TNF_rcpt--assoc_TRAF | PIRSF | TNF receptor-associated factor TRAF |
TRAF-like | Gene3D | TRAF-like |
MATH/TRAF_dom | ProSiteProfiles | MATH/TRAF domain |
MATH/TRAF_dom | SMART | MATH/TRAF domain |
Znf_RING | ProSiteProfiles | Zinc finger, RING-type |
GO Term | Annotation Origin | Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
DNA binding | Hs | molecular function |
tumor necrosis factor receptor binding | Hs | molecular function |
protein binding | Hs | molecular function |
intracellular | Hs | cellular component |
nucleus | Hs | cellular component |
cytoplasm | Hs | cellular component |
cytoskeleton | Hs | cellular component |
plasma membrane | Hs | cellular component |
bicellular tight junction | Hs | cellular component |
apoptotic process | Hs | biological process |
signal transduction | Hs | biological process |
activation of NF-kappaB-inducing kinase activity | Hs | biological process |
multicellular organism development | Hs | biological process |
zinc ion binding | Hs | molecular function |
membrane | Hs | cellular component |
protein kinase binding | Hs | molecular function |
cell junction | Hs | cellular component |
ubiquitin protein ligase binding | Hs | molecular function |
thioesterase binding | Hs | molecular function |
identical protein binding | Hs | molecular function |
regulation of apoptotic process | Hs | biological process |
positive regulation of protein kinase activity | Hs | biological process |
positive regulation of JNK cascade | Hs | biological process |
metal ion binding | Hs | molecular function |
perinuclear region of cytoplasm | Hs | cellular component |
WW domain binding | Hs | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
ubiquitin ligase complex | Hs | cellular component | 167 | 5.25e-46 |
DNA binding | Hs | molecular function | 525 | 0.0 |
ubiquitin-protein transferase activity | Hs | molecular function | 174 | 1.90e-48 |
signal transducer activity | Hs | molecular function | 167 | 5.25e-46 |
receptor binding | Hs | molecular function | 167 | 5.25e-46 |
tumor necrosis factor receptor binding | Hs | molecular function | 525 | 0.0 |
CD40 receptor binding | Hs | molecular function | 167 | 5.25e-46 |
protein binding | Hs | molecular function | 525 | 0.0 |
intracellular | Hs | cellular component | 525 | 0.0 |
nucleus | Hs | cellular component | 525 | 0.0 |
nucleoplasm | Hs | cellular component | 167 | 5.25e-46 |
cytoplasm | Hs | cellular component | 525 | 0.0 |
lipid droplet | Hs | cellular component | 174 | 1.90e-48 |
cytosol | Hs | cellular component | 174 | 1.90e-48 |
cytoskeleton | Hs | cellular component | 525 | 0.0 |
plasma membrane | Hs | cellular component | 525 | 0.0 |
bicellular tight junction | Hs | cellular component | 525 | 0.0 |
cell cortex | Hs | cellular component | 174 | 1.90e-48 |
zinc ion binding | Hs | molecular function | 525 | 0.0 |
lipid binding | Hs | molecular function | 167 | 5.25e-46 |
cytoplasmic side of plasma membrane | Hs | cellular component | 174 | 1.90e-48 |
endosome membrane | Hs | cellular component | 174 | 1.90e-48 |
vesicle membrane | Hs | cellular component | 167 | 5.25e-46 |
membrane | Hs | cellular component | 525 | 0.0 |
transferase activity | Hs | molecular function | 174 | 1.90e-48 |
enzyme binding | Hs | molecular function | 167 | 5.25e-46 |
protein kinase binding | Hs | molecular function | 525 | 0.0 |
protein phosphatase binding | Hs | molecular function | 167 | 5.25e-46 |
cell junction | Hs | cellular component | 525 | 0.0 |
mitogen-activated protein kinase kinase kinase binding | Hs | molecular function | 174 | 1.90e-48 |
ubiquitin conjugating enzyme binding | Hs | molecular function | 174 | 1.90e-48 |
ubiquitin protein ligase binding | Hs | molecular function | 525 | 0.0 |
thioesterase binding | Hs | molecular function | 525 | 0.0 |
macromolecular complex | Hs | cellular component | 174 | 1.90e-48 |
CD40 receptor complex | Hs | cellular component | 174 | 1.90e-48 |
identical protein binding | Hs | molecular function | 525 | 0.0 |
histone deacetylase binding | Hs | molecular function | 174 | 1.90e-48 |
protein kinase B binding | Hs | molecular function | 174 | 1.90e-48 |
membrane raft | Hs | cellular component | 167 | 5.25e-46 |
sphingolipid binding | Hs | molecular function | 167 | 5.25e-46 |
metal ion binding | Hs | molecular function | 525 | 0.0 |
protein N-terminus binding | Hs | molecular function | 174 | 1.90e-48 |
perinuclear region of cytoplasm | Hs | cellular component | 525 | 0.0 |
WW domain binding | Hs | molecular function | 525 | 0.0 |
ubiquitin protein ligase activity | Hs | molecular function | 174 | 1.90e-48 |
TRAF2-GSTP1 complex | Hs | cellular component | 167 | 5.25e-46 |
AIP1-IRE1 complex | Hs | cellular component | 167 | 5.25e-46 |
IRE1-TRAF2-ASK1 complex | Hs | cellular component | 167 | 5.25e-46 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein binding | Gene3D | molecular function | 4.5E-62 |
signal transduction | PIRSF | biological process | 5.9E-67 |
zinc ion binding | PIRSF | molecular function | 5.9E-67 |
regulation of apoptotic process | PIRSF | biological process | 5.9E-67 |